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the dRtf1 component of the Paf1 (show PAF1 Proteins) complex functions in Notch (show NOTCH1 Proteins) signaling
Zebrafish homologues of the yeast Paf1 (show PAF1 Proteins) complex seem to preferentially affect a subset of genes, including Notch (show NOTCH1 Proteins)-regulated genes, during embryogenesis.
Human Rtf1 as a transcription elongation factor (show TSFM Proteins).
Data indicate that the Plus3 domain of the Rtf1 subunit mediates Paf1C recruitment to genes by binding a repeating domain within the phosphorylated elongation factor (show TSFM Proteins) Spt5 (show SUPT5H Proteins).
Potential role of Rtf1 Plus single stranded DNA binding during transcription elongation.
This locus may represent a gene involved in regulation of transcription elongation and chromatin remodeling, based on studies of similar proteins in other organisms. The encoded protein may bind single-stranded DNA.
, Rtf1, Paf1/RNA polymerase II complex component, homolog
, Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
, Paf1/RNA polymerase II complex component
, RNA polymerase-associated Rtf1
, RNA polymerase-associated protein RTF1 homolog
, RNA polymerase-associated protein RTF1 homolog-like
, ortholog of mouse gene trap locus 7
, Rtf1 Paf1/RNA polymerase II complex component homolog
, gene trap locus 7