RRP8 Proteins

(Ribosomal RNA Processing 8 (RRP8))

Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys- 9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and probably acts as a methyltransferase. Its substrates are however unknown.

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RRP8 Protein (AA 1-456) (GST tag)

RRP8 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA

Image no. 1 for Ribosomal RNA Processing 8 (RRP8) (AA 1-456) protein (GST tag) (ABIN1308572)

1 image

Catalog No. ABIN1308572

$475.39

Plus shipping costs $50.00, if applicable $20.00 dry ice

10 μg (More quantities available)

Shipping to: United States

Delivery in 11 to 14 Business Days

Details

RRP8 Protein (AA 1-457) (Strep Tag)

custom-made RRP8 Origin: Mouse Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

Catalog No. ABIN3137122

starts at

$19,692.86

Plus shipping costs $50.00, if applicable $20.00 dry ice

250 μg

Shipping to: United States

Delivery in 55 to 67 Business Days

Details

RRP8 Protein (AA 1-456) (Strep Tag)

custom-made RRP8 Origin: Human Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

Catalog No. ABIN3095127

starts at

$19,692.86

Plus shipping costs $50.00, if applicable $20.00 dry ice

250 μg

Shipping to: United States

Delivery in 55 to 67 Business Days

Details