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anti-Human GRIN2D Antibodies:
anti-Rat (Rattus) GRIN2D Antibodies:
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Human Polyclonal GRIN2D Primary Antibody for ELISA - ABIN314299
Clarke, Johnson: NMDA receptor NR2 subunit dependence of the slow component of magnesium unblock. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2006
High GRIN2D expression is associated with colorectal cancer.
This study showed that the higher GluN2D mRNA level in healthy but not in depressed pregnant women as compared to non-pregnant individuals.
GRIN2D Recurrent De Novo Dominant Mutation Causes a Severe Epileptic Encephalopathy Treatable with NMDA Receptor Channel Blockers
After 7 days of chronic alcohol exposure, there are significant increases in mRNA expression of GRIN2D in cultured neurons derived from alcoholic subjects, but not in cultures from nonalcoholics.
Absence of truncating mutation in GRIN1 (show GRIN1 Antibodies) and GRIN2D genes in patients with autism spectrum disorder and schizophrenia and controls.
In microsatellite instable and microsatellite and chromosomally stable cancers, CIMP and BRAF/KRAS mutations are similarly distributed indicating common mechanisms of tumor initiation or progression in the molecular pathogenesis.
data show that the NMDAR2D was specifically expressed in cultivated keratinocytes
The GluN2D subunit of the NMDA receptor appears to be important for the recognition of individuals and development of normal emotionality in mice. 5-HT2C receptor antagonism may be a therapeutic target for treating social stress-induced anhedonia.
These data provide evidence that interneurons contain synaptic NMDARs possessing a GluN2D subunit, which can influence interneuron function and signal processing.
Presynaptic tri (show VANGL2 Antibodies)-heteromeric GluN2B (show GRIN2B Antibodies)/2D N-methyl-d-aspartate receptors in inhibitory interneurons are likely to mediate the cross talk between excitatory and inhibitory transmission.
These data indicate that the GluN2D NMDA receptor subunits contribute to synaptic activity in the STN (show EEF1A2 Antibodies) and may represent potential therapeutic targets for modulating subthalamic neuron activity in neurological disorders such as Parkinson's disease.
GluN2D expressed at glutamatergic synapses on GABAergic interneurons delays refinement of ascending pathway synapses indirectly.
The expression of the c-fos gene increased the most among phencyclidine-dependent differentially expressed genes between WT and GluN2D knockout out mice.
NMDARs containing the GluN2D subunit contribute to NMDA-induced inhibition of evoked dopamine release and glutamatergic neurotransmission in the striatum of control mice. The inhibitory role is impaired in the 6-hydroxydopamine lesioned striatum.
These findings (a) indicate novel, differential roles for GluN2A (show GRIN2A Antibodies), B and D receptors and for GAD65 (show GAD2 Antibodies)-mediated GABA in the regulation of individual topographies of orofacial movement
The interaction between NR2D and Dock3 (show DOCK3 Antibodies) may have a neuroprotective effect.
GluN2B (show GRIN2B Antibodies)- and GluN2D-containing NMDA receptors play a critical role in N-methyl-D-aspartate-induced excitotoxic retinal cell death.
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D).
glutamate receptor, ionotropic, N-methyl D-aspartate 2D
, NMDAR2D protein
, ionotropic glutamate receptor subunit NR2D
, glutamate [NMDA] receptor subunit epsilon-4-like
, N-methyl D-aspartate receptor subtype 2D
, N-methyl-d-aspartate receptor subunit 2D
, estrogen receptor binding CpG island
, glutamate [NMDA] receptor subunit epsilon-4
, glutamate receptor ionotropic, NMDA 2D
, glutamate receptor, ionotropic, NMDA2D
, glur epsilon 4
, ionotropic NMDA glutamate receptor epsilon 4 subunit type 2