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The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
CD247 antigen, zeta subunit
, CD3Z antigen, zeta polypeptide (TiT3 complex)
, CD3zeta chain
, T-cell antigen receptor complex, zeta subunit of CD3
, T-cell receptor T3 zeta chain
, T-cell surface glycoprotein CD3 zeta chain
, TCR zeta chain
, CD3 antigen, zeta polypeptide
, T-cell receptor T3 eta chain
, CD3 zeta
, CD247 molecule
, CD247 antigen
, T-cell receptor CD3 subunit zeta
, T-cell receptor CD3, subunit zeta
, CD3 zeta chain
, CD3 Zeta chain
, antigen CD3Z, zeta polypeptide
, T-cell receptor zeta chain