Browse our anti-CD86 (CD86) Antibodies

Full name:: anti-CD86 Molecule Antibodies (CD86)

On www.antibodies-online.com are 802 CD86 Molecule (CD86) Antibodies from 35 different suppliers available. Additionally we are shipping CD86 Kits (69) and CD86 Proteins (52) and many more products for this protein. A total of 944 CD86 products are currently listed.

Synonyms:: B7, B7-2, B7.2, B70, Cd28l2, CD28LG2, CLS1, ETC-1, LAB72, Ly-58, Ly58, MB7, MB7-2, TS/A-2

list all antibodies	Gene Name	GeneID	UniProt
	CD86	12524	P42082
	CD86	942	P42081
	CD86	56822
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Most Popular Reactivities for anti-CD86 (CD86) Antibodies

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anti-Mouse (Murine) CD86 Antibodies:

anti-Human CD86 Antibodies:

anti-Rat (Rattus) CD86 Antibodies:

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Relevant Pathways for anti-CD86 Antibodies

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Top referenced anti-CD86 Antibodies

Mouse (Murine) Monoclonal CD86 Primary Antibody for BR, FM - ABIN1176959 : Borriello, Sethna, Boyd, Schweitzer, Tivol, Jacoby, Strom, Simpson, Freeman, Sharpe: B7-1 and B7-2 have overlapping, critical roles in immunoglobulin class switching and germinal center formation. in Immunity 1997 (PubMed)
Show all 17 Pubmed References
Mouse (Murine) Monoclonal CD86 Primary Antibody for IHC (fro), FACS - ABIN2689423 : Bluestone: New perspectives of CD28-B7-mediated T cell costimulation. in Immunity 1995 (PubMed)
Show all 17 Pubmed References
Mouse (Murine) Monoclonal CD86 Primary Antibody for BR, IHC (fro) - ABIN2689420 : Freeman, Borriello, Hodes, Reiser, Hathcock, Laszlo, McKnight, Kim, Du, Lombard: Uncovering of functional alternative CTLA-4 counter-receptor in B7-deficient mice. in Science (New York, N.Y.) 1993 (PubMed)
Show all 15 Pubmed References
Mouse (Murine) Monoclonal CD86 Primary Antibody for FACS - ABIN2689426 : Boussiotis, Gribben, Freeman, Nadler: Blockade of the CD28 co-stimulatory pathway: a means to induce tolerance. in Current opinion in immunology 1995 (PubMed)
Show all 10 Pubmed References
Human Polyclonal CD86 Primary Antibody for IF (p), IHC (p) - ABIN736701 : Evans, Jonason, Bussler, Torno, Veeraraghavan, Reilly, Doherty, Seils, Winter, Mallow, Kirk, Howell, Giralico, Scrivens, Klimatcheva, Fisher, Bowers, Paris, Smith, Zauderer: Antibody blockade of semaphorin 4D promotes immune infiltration into tumor and enhances response to other immunomodulatory therapies. in Cancer immunology research 2015 (PubMed)
Show all 9 Pubmed References
Mouse (Murine) Monoclonal CD86 Primary Antibody for FACS, Func - ABIN457341 : Radhakrishnan, Arneson, Upshaw, Howe, Felts, Colonna, Leibson, Rodriguez, Pease: TREM-2 mediated signaling induces antigen uptake and retention in mature myeloid dendritic cells. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)
Show all 8 Pubmed References
Mouse (Murine) Monoclonal CD86 Primary Antibody for FACS, Func - ABIN457401 : Chung, Wells, Adler, Jacob, Turka, Monroe: Incomplete activation of CD4 T cells by antigen-presenting transitional immature B cells: implications for peripheral B and T cell responsiveness. in Journal of immunology (Baltimore, Md. : 1950) 2003 (PubMed)
Show all 8 Pubmed References
Human Monoclonal CD86 Primary Antibody for FACS, Func - ABIN302014 : Yadav, Judkowski, Flodstrom-Tullberg, Sterling, Redmond, Sherman, Sarvetnick: B7-2 (CD86) controls the priming of autoreactive CD4 T cell response against pancreatic islets. in Journal of immunology (Baltimore, Md. : 1950) 2004 (PubMed)
Show all 9 Pubmed References
Human Monoclonal CD86 Primary Antibody for FACS, Func - ABIN301986 : Vasilevko, Ghochikyan, Holterman, Agadjanyan: CD80 (B7-1) and CD86 (B7-2) are functionally equivalent in the initiation and maintenance of CD4+ T-cell proliferation after activation with suboptimal doses of PHA. in DNA and cell biology 2002 (PubMed)
Show all 9 Pubmed References
Human Monoclonal CD86 Primary Antibody for FACS, Func - ABIN302058 : Caux, Vanbervliet, Massacrier, Azuma, Okumura, Lanier, Banchereau: B70/B7-2 is identical to CD86 and is the major functional ligand for CD28 expressed on human dendritic cells. in The Journal of experimental medicine 1994 (PubMed)
Show all 9 Pubmed References

More Antibodies against CD86 Interaction Partners

Mouse (Murine) CD86 Molecule (CD86) interaction partners

Our results reveal a role for B7-2 as obligatory receptor for superantigens. B7-2 homodimer interface mimotopes prevent superantigen lethality by blocking the superantigen-host costimulatory receptor interaction.
results suggest that the TLR2-p38 (show CRK Antibodies)-CD86 signaling pathway plays a vital role in inflammation associated with burn injury
role with CD40 (show CD40 Antibodies) in primary germinal center generation of distinct antigen-presenting cells
The expression of CD1d (show CD1D Antibodies) showed a significantly negative correlation with CD86 level in B cells from imiquimod (IMQ)-treated mice, B6.MRLlpr mice, and lupus erythematosus (SLE) patients.
B7.2 expressed on skin CD8 (show CD8A Antibodies)(+) T cells supports the survival of Tregs, likely through interaction with its receptor CTLA-4 (show CTLA4 Antibodies), which is highly expressed on skin Tregs.
CTLA-4 (show CTLA4 Antibodies)(+) microvesicles can competitively bind B7 costimulatory molecules on bystander dendritic cells, resulting in downregulation of B7 surface expression.
Low CD86 expression is associated with B16 melanoma.
Local administration of CD86 siRNA during the effector phase ameliorates asthma phenotypes.
Meningococcal capsular polysaccharide-loaded vaccine nanoparticles induce expression of CD86.
The genetic inactivation of B7.1/B7.2 deteriorates obesity-related liver steatosis and metabolic dysregulation, likely a result of the intrinsic absence of Tregs in these mice, rendering DKO mice a novel murine model of NASH (show SAMSN1 Antibodies).

Human CD86 Molecule (CD86) interaction partners

Hepatitis C virus has a genetically determined lymphotropism through co-receptor B7.2.
this study shows that recipients' CD86 gene polymorphisms influence the overall survival after allogeneic hematopoietic stem cell transplantation and, together with CTLA-4 (show CTLA4 Antibodies) polymorphisms, might be considered a risk factor for acute graft versus host disease
results strongly suggest that CD40 (show CD40 Antibodies) and CD86 play a role in the pathophysiology of oral inflammatory diseases such as OLP
Our results reveal a role for B7-2 as obligatory receptor for superantigens. B7-2 homodimer interface mimotopes prevent superantigen lethality by blocking the superantigen-host costimulatory receptor interaction.
Our study reports a novel association of SNPs within CD86 and CTLA4 (show CTLA4 Antibodies) genes with pemphigus. The CD86 rs1129055 A allele appears to confer susceptibility to Pemphigus vulgaris (show DSG3 Antibodies) but not to pemphigus foliaceus (show DSG1 Antibodies).
Our data demonstrate that CML (show BCR Antibodies) patients with high CD86(+)pDC (show PNKD Antibodies) counts have a higher risk of relapse after TKI discontinuation.
The expression of CD1d (show CD1D Antibodies) showed a significantly negative correlation with CD86 level in B cells from imiquimod (IMQ)-treated mice, B6.MRLlpr mice, and lupus erythematosus (SLE) patients.
IL-6 (show IL6 Antibodies), DEC205 (show LY75 Antibodies), and CD86 can be predictive biomarkers for the respiratory and immune effects of ambient PM2.5.
the upregulation of CD86 but not CD80 (show CD80 Antibodies) and PD-L1 (show CD274 Antibodies) on CD68 (show CD68 Antibodies)+ cells in the liver of HBV-infected patients, observed in our study, suggest that the profile of CD68 (show CD68 Antibodies)+ cells does not support the induction of proper Th1 (show TH1L Antibodies) responses that are needed to clear HBV infection. This might provide an explanation for the absence of potent HBV-specific T cells during chronic HBV infection.
CD86 variants association with susceptibility to multiple sclerosis in Iranian population.

Pig (Porcine) CD86 Molecule (CD86) interaction partners

Reduced CD86 antigen is associated with melanoma.
The complete cDNA encoding CD86 molecule of miniature swine was cloned, sequenced and analyzed.

Cow (Bovine) CD86 Molecule (CD86) interaction partners

Northern analysis revealed CD80 (show CD80 Antibodies) and CD86 mRNAs in luteal tissue, with greatest steady-state concentrations at midcycle

CD86 Antigen Profile

Antigen Summary

This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.

Alternative names and synonyms associated with CD86

CD86 molecule (CD86) antibody
CD86 antigen (Cd86) antibody
CD86 molecule (Cd86) antibody

B7 antibody
B7-2 antibody
B7.2 antibody
B70 antibody
Cd28l2 antibody
CD28LG2 antibody
CLS1 antibody
ETC-1 antibody
LAB72 antibody
Ly-58 antibody
Ly58 antibody
MB7 antibody
MB7-2 antibody
TS/A-2 antibody

Protein level used designations for anti-CD86 Molecule (CD86) Antibodies

CD86 antigen , T-lymphocyte activation antigen CD86 , activation B7-2 antigen , early T cell costimulatory molecule-1 , early T-cell costimulatory molecule 1 , B-lymphocyte activation antigen B7-2 , BU63 , CD86 antigen (CD28 antigen ligand 2, B7-2 antigen) , CTLA-4 counter-receptor B7.2 , FUN-1 , cd86 antigen , membrane glycoprotein , B7-2 protein , co-stimulatory molecule B7-2 , costimulatory molecule , CD86/B7-2 costimulatory molecule , B7-1 costimulatory molecule

GENE ID	SPECIES
470900	Pan troglodytes
493704	Felis catus
714390	Macaca mulatta
12524	Mus musculus
942	Homo sapiens
56822	Rattus norvegicus
403764	Canis lupus familiaris
397441	Sus scrofa
414345	Bos taurus
100008999	Oryctolagus cuniculus
554318	Ovis aries

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Show all anti-CD86 Molecule (CD86) Antibodies with Pubmed References