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Browse our Replication Factor C (Activator 1) 3, 38kDa Proteins (RFC3)

Full name:: Replication Factor C (Activator 1) 3, 38kDa Proteins (RFC3)

On www.antibodies-online.com are 8 Replication Factor C (Activator 1) 3, 38kDa (RFC3) Proteins from 4 different suppliers available. Additionally we are shipping Replication Factor C (Activator 1) 3, 38kDa Antibodies (64) and and many more products for this protein. A total of 83 Replication Factor C (Activator 1) 3, 38kDa products are currently listed.

Synonyms:: 21.m02902, 38kDa, 2810416I22Rik, AU022547, cb275, CG5313, Dmel\\CG5313, DmRFC3, DRFC, Recc3, Rfc3, RFC38

list all proteins	Gene Name	GeneID	UniProt
	RFC3	69263	Q8R323
Rat RFC3	RFC3	288414
	RFC3	5983	P40938
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Mouse (Murine) Replication Factor C (Activator 1) 3, 38kDa (RFC3) interaction partners

A1 is a growth-permissive antiapoptotic factor mediating postactivation survival in T cells.

Human Replication Factor C (Activator 1) 3, 38kDa (RFC3) interaction partners

The expression level of RFC3 was markedly upregulated in the HCC tissues and cells.
The expression level of RFC3 was remarkably up-regulated in ovarian cancer OVCAR-3 cells. Down-regulation of RFC3 expression arrested the cell cycle of OVCAR-3 cell in the S-phase and induced apoptosis.
High RFC3 expression is associated with neoplastic myelopoiesis.
our findings suggest that RFC3 protein is an important and independent biomarker with prognostic implications for patients with ovarian carcinoma.
9-cis-RA-activated RXRalpha suppresses the growth of retinoid-sensitive breast cancer and embryonic cells through RFC3.
Data identified RFC3 as a candidate oncogene amplified in esophageal adenocarcinoma (EAC).
RFC3 mutation and loss of RFC3 expression occur in large fractions of gastric and colorectal cancers and suggest that these alterations may contribute to the cancer pathogenesis by deregulating DNA repair and replication.

Replication Factor C (Activator 1) 3, 38kDa (RFC3) Protein Profile

Protein Summary

The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kDa. This gene encodes the 38 kDa subunit. This subunit is essential for the interaction between the 140 kDa subunit and the core complex that consists of the 36, 37, and 40 kDa subunits. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Alternative names and synonyms associated with Replication Factor C (Activator 1) 3, 38kDa (RFC3)

Replication factor C subunit 3 (RfC3)
replication factor C3 (PF14_0601)
replication factor C3 (Chro.30359)
replication factor C3 (PB000006.01.0)
replication factor C3 (PC000345.04.0)
replication factor C subunit 3 (TP04_0380)
replication factor C subunit 3 (Tb09.211.3310)
replication factor C3 (PY04255)
replication factor C3 (PVX_117300)
replication factor C 38 kDa subunit (BBOV_IV003080)
DNA replication factor C complex subunit Rfc3 (SJAG_02182)
replication factor C3, putative (PKH_124240)
replication factor C subunit 3 (rfc3)
replication factor C (activator 1) 3 (Rfc3)
replication factor C subunit 3 (Rfc3)
replication factor C (activator 1) 3 (rfc3)
replication factor C subunit 3 (RFC3)
replication factor C subunit 3 L homeolog (rfc3.L)

21.m02902 protein
38kDa protein
2810416I22Rik protein
AU022547 protein
cb275 protein
CG5313 protein
Dmel\\CG5313 protein
DmRFC3 protein
DRFC protein
Recc3 protein
Rfc3 protein
RFC38 protein

Protein level used designations for RFC3

replication factor C subunit 3 , CG5313-PA , RfC3-PA , drosophila replication factor C , replication factor C3 , A1 38 kDa subunit , RF-C 38 kDa subunit , RFC38 , activator 1 38 kDa subunit , activator 1 subunit 3 , replication factor C 3 , replication factor C 38 kDa subunit , replication factor C, 38 kDa , RFC, 38 kD subunit

GENE ID	SPECIES
34423	Drosophila melanogaster
812183	Plasmodium falciparum 3D7
3414135	Cryptosporidium hominis TU502
3423971	Plasmodium berghei ANKA
3497339	Plasmodium chabaudi chabaudi
3501169	Theileria parva strain Muguga
3660934	Trypanosoma brucei brucei strain 927/4 GUTat10.1
3789846	Plasmodium yoelii yoelii 17XNL
5475053	Plasmodium vivax Sal-1
5477691	Babesia bovis T2Bo
7050157	Schizosaccharomyces japonicus yFS275
7322003	Plasmodium knowlesi strain H
100528456	Ictalurus punctatus
69263	Mus musculus
288414	Rattus norvegicus
259256	Danio rerio
5983	Homo sapiens
734626	Xenopus laevis
418907	Gallus gallus
477308	Canis lupus familiaris
515602	Bos taurus

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