Browse our anti-Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1) Antibodies

Full name:: anti-Heat Shock Protein 90kDa beta (Grp94), Member 1 Antibodies (HSP90B1)

On www.antibodies-online.com are 453 Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1) Antibodies from 32 different suppliers available. Additionally we are shipping Heat Shock Protein 90kDa beta (Grp94), Member 1 Kits (44) and Heat Shock Protein 90kDa beta (Grp94), Member 1 Proteins (13) and many more products for this protein. A total of 520 Heat Shock Protein 90kDa beta (Grp94), Member 1 products are currently listed.

Synonyms:: DDBDRAFT_0206450, DDBDRAFT_0215015, DDB_0206450, DDB_0215015, ECGP, endoplasmin, ERp99, fb61d09, Gp96, Grp94, HSP90B1, hsp108, ppk98, TA-3, Targ2, tra-1, Tra1, wu:fb61d09, wu:fq25g01

list all antibodies	Gene Name	GeneID	UniProt
	HSP90B1	22027	P08113
	HSP90B1	362862	Q66HD0
	HSP90B1	7184	P14625
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Most Popular Reactivities for anti-Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1) Antibodies

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Top referenced anti-Heat Shock Protein 90kDa beta (Grp94), Member 1 Antibodies

Human Polyclonal HSP90B1 Primary Antibody for IHC (f), ICC - ABIN966318 : Green: The illusion of common ground and mythical pluralism. in The International journal of psycho-analysis 2005 (PubMed)
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More Antibodies against Heat Shock Protein 90kDa beta (Grp94), Member 1 Interaction Partners

Rabbit Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1) interaction partners

GRP94 is tightly associated with the cell surface of parietal cells from rabbit gastric mucosa, where it exhibits high-affinity binding for the adenosine receptor agonist NECA and specific inhibitor radicicol.

Mouse (Murine) Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1) interaction partners

Study demonstrated that the lack of gp96 in both the human monocytic cell line MM6 and in macrophages from LysMcre-gp96 floxed mice neither leads to a complete loss of TLR 2 expression nor to a complete loss of TLR-induced signaling, but is associated with an impaired phosphorylation of ERK (show EPHB2 Antibodies) and p38 (show CRK Antibodies). These results reveal for the first time a crucial role for gp96 in the regulation of ERK (show EPHB2 Antibodies) and p38 (show CRK Antibodies) kinases.
GRP94 Knock-out mice exhibits impaired glucose tolerance. GRP94 is an essential regulator of pancreatic beta-cell development, mass, and function.
These data demonstrate the essential role of the gp96-TLR interaction in priming T cell immunity and provide further molecular basis for the coupling of gp96-mediated innate with adaptive immunity.
Heat-shock protein gp96 enhances T cell responses and protective potential to BCG (show SLC11A1 Antibodies) vaccine.
binding of PCSK9 (show PCSK9 Antibodies) to GRP94 protects LDLR (show LDLR Antibodies) from degradation likely by preventing early binding of PCSK9 (show PCSK9 Antibodies) to LDLR (show LDLR Antibodies)
These data indicate that macrophage gp96 is essential for protective immunity during Gram-negative pneumonia
gp96 participates in the generation of natural Treg cells, which might be involved in the control of liver regeneration in the periphery
These studies imply GRP78 (show HSPA5 Antibodies), but not GRP94, is required for mammary gland development.
GRP94 deficiency in the liver led to injury, LPC (show PCSK7 Antibodies) expansion, increased proliferation, activation of oncogenic signaling, progressive repopulation of GRP94-positive hepatocytes and HCC (show FAM126A Antibodies) development in aged mice.
GP96 serves as an essential chaperone for the cell-surface protein (show CD28 Antibodies) glycoprotein A repetitions predominant (GARP (show LRRC32 Antibodies)), which is a docking receptor for latent membrane-associated TGF-beta (show TGFB1 Antibodies) (mLTGF-beta).

Human Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1) interaction partners

Regulation of CLC-1 (show CLCN1 Antibodies) chloride channel (show CLCA1 Antibodies) biosynthesis by FKBP8 (show FKBP8 Antibodies) and Hsp90beta (show HSP90AB1 Antibodies) as a molecular model for myotonia congenita has been described.
Study demonstrated that the lack of gp96 in both the human monocytic cell line MM6 and in macrophages from LysMcre-gp96 floxed mice neither leads to a complete loss of TLR 2 expression nor to a complete loss of TLR-induced signaling, but is associated with an impaired phosphorylation of ERK (show EPHB2 Antibodies) and p38 (show CRK Antibodies). These results reveal for the first time a crucial role for gp96 in the regulation of ERK (show EPHB2 Antibodies) and p38 (show CRK Antibodies) kinases.
HSP-gp96 promotes T cell response, enhances DC antigen presentation and induces cytokine secretion in human gastric cancer cell lines.
our results besides adding further evidence in support of Grp94 as the shared tumor antigen in tumors of the GI tract, prove that it can be measured in plasma as valuable diagnostic marker of disease in the form of complexes with IgG that also exert immune-modulating activities on circulating immune cells.
High GRP94 expression is associated with endometrioid adenocarcinoma.
Immuno-stimulating peptide derived from HMGB1 (show HMGB1 Antibodies) is more effective than the N-terminal domain of Gp96 as an endogenous adjuvant for improvement of protein vaccines.
These data demonstrate the essential role of the gp96-TLR interaction in priming T cell immunity and provide further molecular basis for the coupling of gp96-mediated innate with adaptive immunity.
mutations in GRP94 that affect its IGF chaperone activity represent a novel causal genetic mechanism that limits IGF biosynthesis, quite a distinct mechanism from the known genes in the GH/IGF signaling network.
In this instance, the ATP5B (show ATP5B Antibodies)/CALR (show CALR Antibodies)/HSP90B1/HSPB1 (show HSPB1 Antibodies)/HSPD1 (show HSPD1 Antibodies)-signaling network was revealed as the predominant target which was associated with the majority of the observed protein-protein interactions. As a result, the identified targets may be useful in explaining the anticancer mechanisms of ursolic acid and as potential targets for colorectal cancer therapy.
High HSP90B1 expression is associated with non-small-cell lung cancer.

Pig (Porcine) Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1) interaction partners

structural maturation of the client protein substrate, rather than ATP binding or hydrolysis, serves as the primary signal for dissociation of GRP94-client protein complexes [GRP94]
These results identify a compact, intertwined quaternary conformation of native GRP94

Cow (Bovine) Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1) interaction partners

This study showed that ubiquitinated ALK5 (show TGFBR1 Antibodies) and phosphorylated heat shock protein 27 (show HSP27 Antibodies) specifically accumulate in the cytoskeleton fraction, and ALK1 (show ACVRL1 Antibodies) and ALK5 (show TGFBR1 Antibodies) interact with heat shock protein 90(HSP90 (show HSP90 Antibodies)).

Xenopus laevis Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1) interaction partners

In Xenopus, gp96 can prime CD8(+) T-cell effectors that are not MHC restricted.

Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1) Antigen Profile

Antigen Summary

This gene encodes a member of a family of adenosine triphosphate(ATP)-metabolizing molecular chaperones with roles in stabilizing and folding other proteins. The encoded protein is localized to melanosomes and the endoplasmic reticulum. Expression of this protein is associated with a variety of pathogenic states, including tumor formation. There is a microRNA gene located within the 5' exon of this gene. There are pseudogenes for this gene on chromosomes 1 and 15.

Alternative names and synonyms associated with Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1)

heat shock protein 90kDa beta (Grp94), member 1 (hsp90b1) antibody
heat shock protein Hsp90 family protein (grp94) antibody
94 kD glucose-regulated protein (grp94) antibody
heat shock protein 90 beta family member 1 (HSP90B1) antibody
heat shock protein 90, beta (Grp94), member 1 (Hsp90b1) antibody
heat shock protein 90, beta (grp94), member 1 (hsp90b1) antibody
heat shock protein 90 beta family member 1 (Hsp90b1) antibody
heat shock protein 90kDa beta family member 1 L homeolog (hsp90b1.L) antibody
heat shock protein 90kDa beta (Grp94), member 1 (HSP90B1) antibody

DDBDRAFT_0206450 antibody
DDBDRAFT_0215015 antibody
DDB_0206450 antibody
DDB_0215015 antibody
ECGP antibody
endoplasmin antibody
ERp99 antibody
fb61d09 antibody
Gp96 antibody
Grp94 antibody
HSP90B1 antibody
hsp108 antibody
ppk98 antibody
TA-3 antibody
Targ2 antibody
tra-1 antibody
Tra1 antibody
wu:fb61d09 antibody
wu:fq25g01 antibody

Protein level used designations for HSP90B1

, , , , , , , , , , , , , , , , , , , , , , , , , , tumor rejection antigen (gp96) 1 94 kD glucose-regulated protein endoplasmin endoplasmin-like protein Endoplasmin 94 kDa glucose-regulated protein endoplasmic reticulum resident protein 99 heat shock protein 90 kDa beta member 1 polymorphic tumor rejection antigen 1 transforming growth factor alpha regulated gene 2 tumor rejection antigen gp96 heat shock protein 90kDa beta (grp94), member 1 GRP-94 heat shock protein 90kDa beta (Grp94), member 1 endothelial cell (HBMEC) glycoprotein stress-inducible tumor rejection antigen gp96 tumor rejection antigen 1 98 kDa protein kinase PPK 98 gp96 homolog GRP94 heat shock protein 90kDa beta, member 1 heat shock protein gp96 HSP 108 heat shock 108 kDa protein heat shock protein 108 transferrin-binding protein

GENE ID	SPECIES
734089	Xenopus (Silurana) tropicalis
8622445	Dictyostelium discoideum AX4
100499493	Oncorhynchus mykiss
699568	Macaca mulatta
100033933	Equus caballus
100009456	Oryctolagus cuniculus
22027	Mus musculus
386590	Danio rerio
362862	Rattus norvegicus
7184	Homo sapiens
404019	Canis lupus familiaris
397191	Sus scrofa
282646	Bos taurus
399408	Xenopus laevis
374163	Gallus gallus
452187	Pan troglodytes
100174651	Pongo abelii

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Show all anti-Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1) Antibodies with Pubmed References