Browse our TTF1 Proteins (TTF1)

Human Transcription Termination Factor, RNA Polymerase I (TTF1) interaction partners

1. the TTF-1 protein and mRNA are specifically expressed in schwannomas

2. Human TTF-I localizes in the nucleolus and N-terminus (1-224) of hTTF-I which include nucleolus localization sequence and the expression of Human TTF-I 521-732 increased HIV-I production by regulating transactivation of the LTR promoter.

3. These findings collectively suggest that the triple combination of survivin knockdown with ABT-263 and trametinib treatment, may be a potential strategy for the treatment of KRAS-mutant lung adenocarcinoma. Furthermore, our findings indicate that the welldifferentiated type of KRAS-mutant lung tumors depends, at least in part, on TTF1 for growth.

4. TTF-1 expression may serve as a predictive marker to identify lung cancer patients who may benefit from the addition of bevacizumab to platinum doublet therapy.

5. Our results showed that an approach of using only a two-antibody panel (p40 and TTF-1) might help in reduction of diagnostic category of NSCLC-NOS significantly and contribute in saving tissue for future molecular testing

6. Single nucleotide polymorphism in TTF1 gene is associated with Systemic lupus erythematosus

7. Case Report: KRAS mutation-positive bronchial surface epithelium type lung adenocarcinoma with strong expression of TTF-1.

8. Overexpression of Transcription Termination Factor 1 is Associated with Colorectal Cancer

9. Depletion of TTF-I recapitulates the effects of ARF on ribosomal RNA synthesis and is rescued by the introduction of a TTF-I transgene.

Cow (Bovine) Transcription Termination Factor, RNA Polymerase I (TTF1) interaction partners

1. Ribosomal RNA is maternally inherited and target to DNA independent of transcription, and de novo transcription is required for proper nucleologenesis in cattle.