SIGIRR Proteins
23 Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) Proteins from 6 manufacturers are available on www.antibodies-online.com.
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Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) (AA 1-409) protein (rho-1D4 tag) Protein
Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) (AA 1-118) protein (His tag) Protein
Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) (AA 1-117) protein (His tag) Protein
Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) (AA 140-410) protein (His tag) Protein
Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) (AA 139-409) protein (His tag) Protein
Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) (AA 1-410) protein (rho-1D4 tag) Protein
Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) (AA 1-118) protein (Fc Tag) Protein
Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) (AA 1-118) protein (Fc Tag) Protein
Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) (AA 1-410) protein (GST tag) Protein
Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) (AA 1-117) protein (His tag,GST tag) Protein
Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag) Protein
Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) Protein Protein
Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag) Protein
Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag) Protein
Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) (AA 1-118) protein (His tag) Protein
SIGIRR Protein Profile
Protein Summary
Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP (By similarity).
Alternative names and synonyms associated with SIGIRR
- single Ig and TIR domain containing (SIGIRR) antibody
- single immunoglobulin and toll-interleukin 1 receptor (TIR) domain (Sigirr) antibody
- single immunoglobulin and toll-interleukin 1 receptor (TIR) domain (sigirr) antibody
- single Ig and TIR domain containing (Sigirr) antibody
- AI256711 antibody
- RGD1306732 antibody
- sc:d148 antibody
- TIR8 antibody
Protein level used designations for SIGIRR
single Ig IL-1-related receptor , single Ig IL-1R-related molecule , single immunoglobulin domain IL1R1 related , single immunoglobulin domain-containing IL1R-related protein , toll/interleukin-1 receptor 8 , single Ig IL-1 receptor related protein , single Ig IL-1R-related protein , TIR8
GENE ID | SPECIES |
---|---|
59307 | Homo sapiens |
24058 | Mus musculus |
563606 | Danio rerio |
422995 | Gallus gallus |
531801 | Bos taurus |
309106 | Rattus norvegicus |