Browse our SIGIRR Proteins (SIGIRR)

Full name:: Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain Proteins (SIGIRR)

On www.antibodies-online.com are 21 Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) Proteins from 7 different suppliers available. Additionally we are shipping SIGIRR Antibodies (70) and SIGIRR Kits (5) and many more products for this protein. A total of 107 SIGIRR products are currently listed.

Synonyms:: AI256711, RGD1306732, sc:d148, TIR8

list all proteins	Gene Name	GeneID	UniProt
	SIGIRR	59307	Q6IA17
	SIGIRR	24058	Q9JLZ8
	SIGIRR	309106	Q4V892
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SIGIRR Proteins (SIGIRR) by Origin

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Relevant Pathways for SIGIRR Proteins

Toll-Like Receptors Cascades

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More Proteins for SIGIRR Interaction Partners

Human Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) interaction partners

Mouse (Murine) Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) interaction partners

Zebrafish Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) interaction partners

Cow (Bovine) Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) interaction partners

SIGIRR Protein Profile

Protein Summary

Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP (By similarity).

Alternative names and synonyms associated with SIGIRR

single Ig and TIR domain containing (SIGIRR)
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain (Sigirr)
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain (sigirr)
single Ig and TIR domain containing (Sigirr)

AI256711 protein
RGD1306732 protein
sc:d148 protein
TIR8 protein

Protein level used designations for SIGIRR

single Ig IL-1-related receptor , single Ig IL-1R-related molecule , single immunoglobulin domain IL1R1 related , single immunoglobulin domain-containing IL1R-related protein , toll/interleukin-1 receptor 8 , single Ig IL-1 receptor related protein , single Ig IL-1R-related protein , TIR8

GENE ID	SPECIES
59307	Homo sapiens
24058	Mus musculus
563606	Danio rerio
422995	Gallus gallus
531801	Bos taurus
309106	Rattus norvegicus

Selected quality suppliers for SIGIRR Proteins (SIGIRR)

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