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SIGIRR Proteins

23 Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) Proteins from 6 manufacturers are available on www.antibodies-online.com.

23 results:

Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) (AA 1-409) protein (rho-1D4 tag) Protein

SIGIRR Origin: Mouse Source: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3130345
$5,919.98
Plus shipping costs $45.00 and $24.00 dry ice
0.25 mg (More quantities available)
local_shipping Shipping to: United States
Delivery in 50 to 55 Business Days
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Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) (AA 1-117) protein (His tag) Protein

SIGIRR Origin: Mouse Source: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3130344
$6,041.45
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Delivery in 30 to 35 Business Days
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Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) (AA 1-118) protein (His tag) Protein

SIGIRR Origin: Human Source: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3076818
$6,041.45
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Delivery in 30 to 35 Business Days
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Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) (AA 139-409) protein (His tag) Protein

SIGIRR Origin: Mouse Source: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3130346
$7,594.15
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Will be delivered in 50 Business Days
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Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) (AA 140-410) protein (His tag) Protein

SIGIRR Origin: Human Source: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3076819
$7,594.15
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Will be delivered in 50 Business Days
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Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) (AA 1-410) protein (rho-1D4 tag) Protein

SIGIRR Origin: Human Source: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3095386
$8,431.43
Plus shipping costs $45.00 and $24.00 dry ice
0.5 mg (More quantities available)
local_shipping Shipping to: United States
Delivery in 50 to 55 Business Days
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Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) (AA 1-118) protein (Fc Tag) Protein

SIGIRR Origin: Human Source: Human Cells Recombinant (96.8+1.6) % as determined by SDS-PAGE SDS
Catalog No. ABIN2005083
$328.16
Plus shipping costs $45.00
100 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 11 to 13 Business Days
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Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) (Extracellular Domain), (AA 1-118) protein (His tag) Protein

SIGIRR Origin: Human Source: Human Cells Recombinant > 95 % as determined by SDS-PAGE SDS
Catalog No. ABIN2005085
$328.16
Plus shipping costs $45.00
100 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 11 to 13 Business Days
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Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) (AA 1-117) protein (Fc Tag,His tag) Protein

SIGIRR Origin: Mouse Source: Human Cells Recombinant > 95 % as determined by SDS-PAGE SDS
Catalog No. ABIN2007357
$328.16
Plus shipping costs $45.00
100 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 11 to 13 Business Days
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Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) (AA 1-410) protein (GST tag) Protein

SIGIRR Origin: Human Source: Wheat germ Recombinant AP, AA, ELISA, WB
Catalog No. ABIN1319981
$414.29
Plus shipping costs $45.00 and $24.00 dry ice
10 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 11 to 12 Business Days
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  • Type Protein
    • Protein
  • Target Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR)
    • Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR)
    • Hemagglutinin (HA)
    • Ribosome Binding Factor A (RBFA)
    • Tumor Necrosis Factor alpha (TNF)
    • S-Adenosyl-Methionine Synthase (METK)
    • Interleukin 6 (IL6)
    • Interferon gamma (IFNG)
    • Hemoglobin beta (HBB)
    • Triosephosphate Isomerase 1 (TPI1)
    • Thymidylate Kinase (Tmk)
    • Interleukin 4 (IL4)
    • Interleukin 2 (IL2)
    • Interleukin 1, beta (IL1B)
    • Uracil-DNA Glycosylase (UNG)
    • Fibroblast Growth Factor 2 (Basic) (FGF2)
    • Growth Hormone 1 (GH1)
    • Lipoyl synthase lipA
    • Interleukin 10 (IL10)
    • KIT Ligand (KITLG)
    • Malate Dehydrogenase (MDH)
    • Insulin-Like Growth Factor 1 (IGF1)
    • Epidermal Growth Factor (EGF)
    • Leptin (LEP)
    • Interleukin 8 (IL8)
    • Interleukin 3 (IL-3)
    • Myoglobin (MB)
    • Queuine tRNA-Ribosyltransferase 1 (QTRT1)
    • Hemoglobin, alpha 1 (HBA1)
    • serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1)
    • phosphatidylserine Decarboxylase (PISD)
    • Interleukin 1 alpha (IL1A)
    • CD40 Ligand (CD40LG)
    • Prolactin (PRL)
    • Interleukin 13 (IL13)
    • Vascular Endothelial Growth Factor A (VEGFA)
    • Chemokine (C-X-C Motif) Ligand 12 (CXCL12)
    • Albumin (ALB)
    • Aspartate Carbamoyltransferase (PYRB)
    • Phosphoglucosamine Mutase (GLMM)
    • Porphobilinogen Deaminase (HEMC)
    • Interleukin 15 (IL15)
    • Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA)
    • beta-2-Microglobulin (B2M)
    • Chemokine (C-C Motif) Ligand 2 (CCL2)
    • Gp120
    • Interleukin 33 (IL33)
    • Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2)
    • Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)
    • Fibroblast Growth Factor 1 (Acidic) (FGF1)
    • Adiponectin (ADIPOQ)
    • Ferrochelatase, HEMH (HEMH)
  • Application
    • ELISA
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • Immunoprecipitation (IP)
    • Crystallization (Crys)
    • Antibody Production (AbP)
    • Functional Studies (Func)
    • Protein Interaction (PI)
    • Standard (STD)
    • Affinity Purification (AP)
    • Antibody Array (AA)
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Images available
  • Host
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Insect Cells
    • Human Cells
    • Yeast
    • Wheat germ
  • Binding Specificity
    • AA 1-118
    • AA 1-117
    • AA 1-410
    • AA 1-409
    • AA 139-409
    • AA 140-410
    • Extracellular Domain
    • Transcript Variant 1
    • Transcript Variant 2
    • Transcript Variant 3
  • Conjugate
    • Un-conjugated
    • His tag
    • Fc Tag
    • Myc-DYKDDDDK Tag
    • rho-1D4 tag
    • Fc Tag,His tag
    • GST tag
    • His tag,GST tag
  • Protein Type
    • Recombinant
  • Format
    • Liquid
    • Lyophilized

SIGIRR Protein Profile

Protein Summary

Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP (By similarity).

Alternative names and synonyms associated with SIGIRR

  • single Ig and TIR domain containing (SIGIRR) antibody
  • single immunoglobulin and toll-interleukin 1 receptor (TIR) domain (Sigirr) antibody
  • single immunoglobulin and toll-interleukin 1 receptor (TIR) domain (sigirr) antibody
  • single Ig and TIR domain containing (Sigirr) antibody
  • AI256711 antibody
  • RGD1306732 antibody
  • sc:d148 antibody
  • TIR8 antibody

Protein level used designations for SIGIRR

single Ig IL-1-related receptor , single Ig IL-1R-related molecule , single immunoglobulin domain IL1R1 related , single immunoglobulin domain-containing IL1R-related protein , toll/interleukin-1 receptor 8 , single Ig IL-1 receptor related protein , single Ig IL-1R-related protein , TIR8

GENE ID SPECIES
59307 Homo sapiens
24058 Mus musculus
563606 Danio rerio
422995 Gallus gallus
531801 Bos taurus
309106 Rattus norvegicus

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