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Aconitase 1 Antigen Profile
Catalyzes the isomerization of citrate to isocitrate via cis-aconitate (By similarity). Iron sensor. Binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. Functions as mRNA binding protein that regulates uptake, sequestration and utilization of iron when cellular iron levels are low. Binds to iron-responsive elements (IRES) in target mRNA species when iron levels are low. Binding of a 4Fe-4S cluster precludes RNA binding (By similarity).
Alternative names and synonyms associated with Aconitase 1
aconitase 1 (Aco1) ELISA Kit
AI256519 ELISA Kit
Aco-1 ELISA Kit
Irebp ELISA Kit
Irp1 ELISA Kit
Protein level used designations for Aconitase 1
, citrate hydro-lyase
, cytoplasmic aconitase
, cytoplasmic aconitate hydratase
, iron regulatory protein 1
, iron-responsive element-binding protein 1