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anti-Mouse (Murine) Antibodies:
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these results demonstrate that MT2 (show MTNR1B Antibodies) plays a role in CD4 (show CD4 Antibodies)+ T cell activation by transducing reactive oxygen species signals into an increased [Zn2+]i that subsequently affects downstream effector function
Cardioprotective effects of MT1 (show MT1 Antibodies)/2 seem to be exerted via modulation of contractile elements, antioxidative enzymes, inflammatory response, and myocardial remodeling.
Metallothioneins may have a protective role against post-burn inflammation and inflammatory organ damage, at least partly through inhibiting the p38 MAPK (show MAPK14 Antibodies) signaling.
Enhanced senescence due to absence of metallothionein (show MT Antibodies) genes may shorten lifespan.
The MT2 (show MTNR1B Antibodies) receptor activates Akt (show AKT1 Antibodies)/GSK-3beta/CRMP-2 (show DPYSL2 Antibodies) signaling and is necessary and sufficient to mediate functional axonogenesis and synaptic formation in central neurons.
MT1 (show MT1 Antibodies)/2 deficiency aggravated depleted uruanium-induced nephrotoxicity, and the molecular mechanisms appeared to be related to the increased oxidative stress and apoptosis, and decreased SGLT expression.
Zinc-binding MT1 (show MT1 Antibodies) and MT2 (show MTNR1B Antibodies) are key modulators of Fc epsilonRI-induced basophil production of IL-4 (show IL4 Antibodies).
Metallothionein (show MT Antibodies) blocks oxidative DNA damage induced by acute inorganic arsenic exposure
the metal binding abilities of mouse MT2 (show MTNR1B Antibodies) (mMT2) with divalent (Zn(II) and Cd(II)) and monovalent (Cu(I)) ions were analyzed and compared to those of the mouse MT1 (show MT1 Antibodies) (mMT1) isoform.
The results of this study suggest that metallothioneins may play a key role in protecting the kidney against high glucose-induced ROS (show ROS1 Antibodies) and subsequent inflammation in diabetic nephropathy.
Report expression of similar to metallothionein-B(smt-B) upon cadmium exposure and cold shock in zebrafish (Danio rerio).
mt2 and smtb may play an important role in neurogenesis and neuroprotection.
data not only reveal a non-canonical function of Mt2 in angiogenesis, but also propose Mt2 as a novel regulator of vegfc (show VEGFC Antibodies) expression.
Metallothioneins have a high content of cysteine residues that bind various heavy metals\; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.
, Metallothionein 2
, metallothionein IIA
, metallothionein IIB
, metallothionein II