Browse our anti-Oxidative-Stress Responsive 1 (OXSR1) Antibodies

Full name:: anti-Oxidative-Stress Responsive 1 Antibodies (OXSR1)

On www.antibodies-online.com are 119 Oxidative-Stress Responsive 1 (OXSR1) Antibodies from 18 different suppliers available. Additionally we are shipping Oxidative-Stress Responsive 1 Proteins (9) and Oxidative-Stress Responsive 1 Kits (7) and many more products for this protein. A total of 150 Oxidative-Stress Responsive 1 products are currently listed.

Synonyms:: 2210022N24Rik, 2810422B09Rik, AI462649, AW209236, C20orf111, dJ1183I21.1, HSPC207, mKIAA1101, odd1, osr1, Perit1, zgc:55494, zgc:77321

list all antibodies	Gene Name	GeneID	UniProt
	OXSR1	9943	O95747
	OXSR1	108737	Q6P9R2
	OXSR1	316064
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Most Popular Reactivities for anti-Oxidative-Stress Responsive 1 (OXSR1) Antibodies

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Top referenced anti-Oxidative-Stress Responsive 1 Antibodies

Human Monoclonal OXSR1 Primary Antibody for ELISA, WB - ABIN564274 : Chiga, Rafiqi, Alessi, Sohara, Ohta, Rai, Sasaki, Uchida: Phenotypes of pseudohypoaldosteronism type II caused by the WNK4 D561A missense mutation are dependent on the WNK-OSR1/SPAK kinase cascade. in Journal of cell science 2011 (PubMed)
Show all 5 Pubmed References
Human Monoclonal OXSR1 Primary Antibody for IF, ELISA - ABIN564266 : Naguro, Umeda, Kobayashi, Maruyama, Hattori, Shimizu, Kataoka, Kim-Mitsuyama, Uchida, Vandewalle, Noguchi, Nishitoh, Matsuzawa, Takeda, Ichijo: ASK3 responds to osmotic stress and regulates blood pressure by suppressing WNK1-SPAK/OSR1 signaling in the kidney. in Nature communications 2012 (PubMed)
Show all 2 Pubmed References
Human Monoclonal OXSR1 Primary Antibody for ELISA, WB - ABIN564275 : Susa, Sohara, Rai, Zeniya, Mori, Mori, Chiga, Nomura, Nishida, Takahashi, Isobe, Inoue, Takeishi, Takeda, Sasaki, Uchida: Impaired degradation of WNK1 and WNK4 kinases causes PHAII in mutant KLHL3 knock-in mice. in Human molecular genetics 2014 (PubMed)
Human Polyclonal OXSR1 Primary Antibody for ICC, IF - ABIN4342122 : Stadler, Hjelmare, Neumann, Jonasson, Pepperkok, Uhlén, Lundberg: Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy. in Journal of proteomics 2012 (PubMed)

More Antibodies against Oxidative-Stress Responsive 1 Interaction Partners

Human Oxidative-Stress Responsive 1 (OXSR1) interaction partners

Data demonstrate that hypotonic low-chloride conditions that activate the WNK1 (show WNK1 Antibodies)-SPAK (show STK39 Antibodies) and OSR1 pathway promote phosphorylation of NKCC2 (show SLC12A1 Antibodies) isoforms.
OSR1 and SPAK (show STK39 Antibodies) integrate signals from osmosensing and survival pathways.
our data show a novel role for the WNK1 (show WNK1 Antibodies)/OSR1/NKCC1 (show SLC12A2 Antibodies) pathway in glioma migration
SPAK (show STK39 Antibodies) and OSR1 are powerful negative regulators of the cell volume regulatory Cl- channel ClC-2 (show CLCN2 Antibodies)
study identifies a separation of functions for the WNK1 (show WNK1 Antibodies)-activated protein kinases OSR1 and SPAK (show STK39 Antibodies) in mediating proliferation, invasion, and gene expression in endothelial cells
The CCT (show FLVCR2 Antibodies) domain directly interacts with the kinase domain to block substrate access and inhibit the domain-swapped homodimerization of the kinase domain of OSR1.
WNK 1 (show WNK1 Antibodies), 3, 4, OSR1, and SPAK (show STK39 Antibodies) signaling system known to play a role in regulating the phosphorylation status, and hence activity of the CCCs in other tissues, is also present in the rat and human lenses.
OSR1 has the capacity to downregulate the peptide transporters PEPT1 (show SLC15A1 Antibodies) and PEPT2 (show SLC15A2 Antibodies) by decreasing the carrier protein abundance in the cell membrane
Both, SPAK (show STK39 Antibodies) and OSR1, are negative regulators of the creatine transporter SLC6A8 (show SLC6A8 Antibodies)
SPAK (show STK39 Antibodies) and OSR1 are negative regulators of EAAT3 (show SLC1A1 Antibodies) activity

Mouse (Murine) Oxidative-Stress Responsive 1 (OXSR1) interaction partners

increased phosphorylation of Na(+)-K(+)-2Cl(-) cotransporter in obesity and identifies a new role for AMP-activated protein kinase in regulating the activity of oxidative stress responsive 1 kinase-related proline-alanine-rich protein kinase
OSR1 (show OSR1 Antibodies) is expressed in intestine and partial WNK insensitivity of OSR1 (show OSR1 Antibodies) increases intestinal Na( )/H( ) exchanger activity and colonic epithelium Na( ) channel activity
Data indicate that SPAK (show STK39 Antibodies) and OSR1 (show OSR1 Antibodies) function interdependently in the distal convoluted tubule (DCT (show DCT Antibodies)) to positively regulate thiazide-sensitive sodium-chloride cotransporter (show SLC12A3 Antibodies), NCC (show SLC12A3 Antibodies).
Partial OSR1 (show OSR1 Antibodies) deficiency influences Na(+)/H(+) exchanger activity, ROS (show ROS1 Antibodies) formation, and migration of dendritic cells.
Results clearly establish that PHAII caused by the WNK4 (show WNK4 Antibodies) D561A mutation is dependent on the activation of the WNK-OSR1 (show OSR1 Antibodies)/SPAK (show STK39 Antibodies)-NCC (show SLC12A3 Antibodies) cascade.
Two Ste20-like (show STK25 Antibodies) kinases that bind and phosphorylate NKCC1 (show SLC12A2 Antibodies): Ste20 (show STK24 Antibodies)-related proline-alanine-rich kinase (SPAK (show STK39 Antibodies)) and oxidative-stress response 1 (OSR1 (show OSR1 Antibodies)), were identified.
In the kidneys, NKCC2 (show SLC12A1 Antibodies) but not NCC (show SLC12A3 Antibodies) is the main target of OSR1 (show OSR1 Antibodies) and the reduced p-NKCC2 (show SLC12A1 Antibodies) in KSP-OSR1 (show OSR1 Antibodies)(-/-) mice may lead to a Bartter-like syndrome.
phosphorylation states of NCC (show SLC12A3 Antibodies) and OSR1 (show OSR1 Antibodies)/SPAK (show STK39 Antibodies) (Gene: Oxsr1, GeneID: 108737) were increased by low-salt diets and decreased by high-salt diets
OSR1 (show OSR1 Antibodies), a kinase closely related to SPAK (show STK39 Antibodies), exhibited similar kinase properties and similar functional activation of NKCC1 (show SLC12A2 Antibodies) when coexpressed with WNK4 (show WNK4 Antibodies).
review: NCC (show SLC12A3 Antibodies) in the distal convoluted tubule plays a critical role in NaCl and, indirectly, in K+ homeostasis; regulation by SPAK (show STK39 Antibodies)/OSR1 (show OSR1 Antibodies) kinases and WNKs.

Pig (Porcine) Oxidative-Stress Responsive 1 (OXSR1) interaction partners

The gene shows 92.8% nucleotide identity and 95.5% amino acid identity with human OSR1 (show OSR1 Antibodies).

Oxidative-Stress Responsive 1 (OXSR1) Antigen Profile

Antigen Summary

The product of this gene belongs to the Ser/Thr protein kinase family of proteins. It regulates downstream kinases in response to environmental stress, and may play a role in regulating the actin cytoskeleton.

Alternative names and synonyms associated with Oxidative-Stress Responsive 1 (OXSR1)

oxidative stress responsive 1 (OXSR1) antibody
oxidative stress responsive serine rich 1 (OSER1) antibody
oxidative stress responsive 1b (oxsr1b) antibody
serine/threonine-protein kinase OSR1 (CpipJ_CPIJ015177) antibody
serine/threonine-protein kinase OSR1 (Tsp_00299) antibody
oxidative-stress responsive 1 (Oxsr1) antibody
oxidative stress responsive 1 (Oxsr1) antibody
oxidative-stress responsive 1 (oxsr1) antibody

2210022N24Rik antibody
2810422B09Rik antibody
AI462649 antibody
AW209236 antibody
C20orf111 antibody
dJ1183I21.1 antibody
HSPC207 antibody
mKIAA1101 antibody
odd1 antibody
osr1 antibody
Perit1 antibody
zgc:55494 antibody
zgc:77321 antibody

Protein level used designations for OXSR1

oxidative stress-responsive 1 protein , oxidative-stress responsive 1 , serine/threonine-protein kinase OSR1 , oxidative stress-responsive 1 , oxidative stress-responsive protein 1 , oxidative stress-responsive serine-rich protein 1 , peroxide-inducible transcript 1 protein

GENE ID	SPECIES
9943	Homo sapiens
51526	Homo sapiens
394150	Danio rerio
6048779	Culex quinquefasciatus
10901611	Trichinella spiralis
100174028	Pongo abelii
108737	Mus musculus
316064	Rattus norvegicus
607809	Canis lupus familiaris
100050017	Equus caballus
397618	Sus scrofa
100722234	Cavia porcellus
446771	Xenopus laevis

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Show all anti-Oxidative-Stress Responsive 1 (OXSR1) Antibodies with Pubmed References