Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all synonyms
Select your origin of interest
active involvement in placental development and important role in pathology of pregnancy
Systemic and local levels of sFRP3 protein are downregulated in osteosarcoma.
we observed that FRZB regulates integrin beta1D expression, its silencing increasing integrin beta1D expression to levels similar to those in controls.
endogenous expression of the WNT antagonists DKK1 and FRZB is necessary for multiple steps during chondrogenesis
this study shows that sFRP3 regulates fibroblast-like synociocyte transformation
This may suggest that SFRP3 acts as an agonist of Wnt signaling and promotes invasive behavior.
The secreted frizzled-related protein and disheveled protein family members appear to be actively involved in the pathogenesis of primary testicular germ cell tumors.
FRZB expression was up-regulated in hepatocellular carcinoma bone metastasis tissue, which suggested that FRZB might play a key role in the HCC bone metastasis.
Positive expression of FRZB was statistically significantly associated with poor prognosis of patients with colon carcinoma hepatic metastasis.
Secreted Frizzled-Related Protein 3 (SFRP3) Is Required for Tumorigenesis of PAX3-FOXO1-Positive Alveolar Rhabdomyosarcoma
Intermediate SFRP3 levels are associated with better survival and fewer cardiovascular events than low or high SFRP3 levels, independently of conventional risk factors, in older patients with chronic systolic Heart Failure of ischemic origin.
Intermediate levels of sFRP3 were a predictor of all-cause mortality and re-hospitalization in acute coronary syndromes.
Data suggest secreted FRP3 (frizzled related protein-3) interacts with ADAM17 (A disintegrin/metalloprotease 17) substrate IL6R (interleukin-6 receptor) release; this interaction is down-regulated in osteoarthritis due to rare double variant in FRP3.
study indicates that increased expression of both SFRP1 and SFRP3 may contribute to the pathogenesis of IUGR placental dysfunction, whereas the loss of these proteins may be involved in the development of human trophoblastic tumors.
These data indicate an important role of methylation-induced gene silencing of the sFRP gene family in human GBM.
Our results suggest that the sFRP3 c.970C>G and sFRP4 c.958C>A polymorphisms may be genetic factors associated with the prevalence of osteoporosis at the femoral neck in postmenopausal Korean women.
Promoter hypermethylation of SFRP3 is a common event hepatocellular carcinoma.
FRZB knockdown may upregulate the Wnt/betacatenin pathway and promote aggressiveness in gastric cancer.
The compound heterozygosity for mutations in the MFRP gene described in the present study should severely affect the function of MFRP by completely removing the cubilin, LDL-A and frizzled-related CRD domains.
Data indicate an inverse correlation between osteoarthritis and GREM1, FRZB and DKK1 gene expression.
The protein encoded by this gene is a secreted protein that is involved in the regulation of bone development. Defects in this gene are a cause of female-specific osteoarthritis (OA) susceptibility.
frizzled-related protein 1
, secreted frizzled-related protein 3
, secreted frizzled-related sequence protein 3
, frizzled homolog-related