Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species and application
anti-Human FZD1 Antibodies:
anti-Rat (Rattus) FZD1 Antibodies:
anti-Mouse (Murine) FZD1 Antibodies:
Go to our pre-filtered search.
Human Polyclonal FZD1 Primary Antibody for WB - ABIN389235
Zhang, Kuipers, Yerges-Armstrong, Nestlerode, Jin, Wheeler, Patrick, Bunker, Zmuda: Functional and association analysis of frizzled 1 (FZD1) promoter haplotypes with femoral neck geometry. in Bone 2010
Show all 4 Pubmed References
Human Polyclonal FZD1 Primary Antibody for IHC (p), ELISA - ABIN543565
Yang, Yamasaki, Shirakata, Dai, Tokumaru, Yahata, Tohyama, Hanakawa, Sayama, Hashimoto: Bone morphogenetic protein-2 modulates Wnt and frizzled expression and enhances the canonical pathway of Wnt signaling in normal keratinocytes. in Journal of dermatological science 2006
Show all 3 Pubmed References
Human Polyclonal FZD1 Primary Antibody for ELISA, WB - ABIN543564
Hardie, Korfhagen, Sartor, Prestridge, Medvedovic, Le Cras, Ikegami, Wesselkamper, Davidson, Dietsch, Nichols, Whitsett, Leikauf: Genomic profile of matrix and vasculature remodeling in TGF-alpha induced pulmonary fibrosis. in American journal of respiratory cell and molecular biology 2007
Show all 3 Pubmed References
Human Monoclonal FZD1 Primary Antibody for CyTOF, FACS - ABIN4900481
Baksh, Boland, Tuan: Cross-talk between Wnt signaling pathways in human mesenchymal stem cells leads to functional antagonism during osteogenic differentiation. in Journal of cellular biochemistry 2007
The stabilizing function of Prickle on Frizzled requires Prickle activity in neighboring cells. Conversely, Prickle in the same cell has a destabilizing effect on Frizzled.
The transmembrane proteins Frizzled and Flamingo form a stoichiometric nucleus in the complex, while the relative levels of the other four core proteins can vary independently.we show that robust cell polarization is achieved over a range of complex stoichiometries but is dependent on maintaining appropriate levels of the components Frizzled and Strabismus.
instructive input of Frizzled-Planar cell polarity (Fz/PCP) signalling into polarized centriole positioning in Drosophila wings, is reported.
Studies indicate that Frizzled (Fz) is constitutively ubiquitinated and internalized to the early endosome.
These data are the first to show that Netrin and Frazzled regulate the placement of gap junctions presynaptically at a synapse.
We found no evidence for an essential requirement of the Fz C-terminal tail downstream of the KTxxxW motif in planar polarity and canonical Wnt signaling.
Frizzled-dependent planar polarity pathway locally promotes E-cadherin turnover via recruitment of RhoGEF2.
Dissecting the molecular bridges that mediate the function of Frizzled in planar cell polarity.
Frazzled is expressed and cell autonomously required in R8 photoreceptors for directing their axons to the medulla-neuropil layer M3.
Frizzled and Dishevelled are enriched at distal sides of each cell and hence localize at the interface with ligand-expressing cells in the non-responding cells.
Knockdown of Tc-fz1 alone interfered with the formation of the proximo-distal and the dorso-ventral axes during leg development, whereas no effect was observed with single Tc-fz2 or Tc-fz4 RNAi knockdowns.
Data show that ds and fz contribute independently to planar polarity in the Drosophila ventral epidermis and that they do so over spatially distinct domains.
The goal of this study was to investigate the role of the Ft/Ds pathway in the context of Fz planar cell polarity signaling model.
Results describe a Frizzled-Dishevelled-NuMA/Mud pathway that orients division from Drosophila to vertebrates.
dAbl positively regulates the Fz/Dishevelled (Dsh) PCP pathway without affecting canonical Wnt/Wg-Fz signaling
A balance of ubiquitylation and deubiquitylation of the Wg/Wnt receptor Frizzled determines the cellular responsiveness to Wg/Wnt both in mammalian cells and in Drosophila.
Correct specification of a single R3 cell per ommatidium is essential for the normal interpretation of the Fz-mediated polarity signal.
Frizzled is involved in positional information signaling during development in the coordinated orientation of ommatidia in the Drosophila eye.
Function is dependent on inturned protein and on fuzzy protein.
Asymmetric localization of frizzled and the determination of notch-dependent cell fate in the Drosophila eye.
FZD1 and CAIX might be important biological markers for the carcinogenesis, metastasis, invasion, and prognosis of pancreatic ductal adenocarcinoma
aken together, our results suggest that Sp1 plays a role in human osteoblast differentiation and mineralization, which is at least partially mediated by Sp1-dependent transactivation of FZD1.
The amplification of miR-135b suppressed non-small cell lung cancer chemoresistance by directly mediating FZD1 down-regulation.
Our study suggests that Sox9 siRNA inhibits the proliferation capability of human osteosarcoma cells by down-regulating the expression of Wnt1 and its receptor Fzd1
FZD1 expression was down-regulated by AP2 expression and mediated osteoblast differentiation and mineralization.
our data demonstrate that FZD1 regulates PKCdelta, and the PKCdelta/AP-1 signalling transduction pathway plays an important role in drug resistance in MES-SA/Dx5 cells.
Polymorphisms in several genes involved in the Wnt signaling pathway were associated with hepatic fibrosis or inflammation risk in HCV-infected males.
ACE2 and FZD1 are prognosis markers in squamous cell/adenosquamous carcinoma and adenocarcinoma of gallbladder.
Experiments demonstrate a role of E2F1 in osteoblast differentiation and mineralization and suggest that FZD1 is required, in part, for E2F1 regulation of osteoblast mineralization.
Fz1 is a Wnt responsive gene in colon-derived tissues. Fz1 expression exhibited increased expression in normal mucosa only in close proximity to colon cancer
FZD1 appears to mediate multidrug resistance by regulating the Wnt/beta-catenin pathway
Soluble FZC18 and Wnt3a physically interact in a cell-free system and soluble FZC18 binds the frizzled 1 and 8 receptors.
These results suggest that FZD1 expression is regulated in a haplotype-dependent manner in osteoblasts and that these same haplotypes may be associated with biomechanical indices of bone strength.
Fz1 and LRP1 bind, which disrupts the receptor/coreceptor complex formation and leads to the repression of the canonical Wnt signaling
subcellular Fz localization, through the association with other membrane proteins, is a critical aspect in regulating the signaling specificity within the Wnt/Fz signaling pathways
Bone morphogenetic protein-2 modulates Wnt and frizzled expression and enhances the canonical pathway of Wnt signaling in normal keratinocytes
Data demonstrate that Frizzled receptors can functionally replace mating factor receptors in yeast and offer an experimental system to study modulators of Frizzled receptors.
a frizzled module in cell surface collagen 18 inhibits Wnt/beta-catenin signaling
a cis-regulatory polymorphism in the FZD1 promoter region may have a functional role in determining bone structural geometry
The proportion of frizzled-1 positive ovaries was lower in normal patients than in those with ovarian cancer or bening neoplasia
FZD1 regulates specific stages of adult hippocampal neurogenesis.
Suppressed expression of Fzd1 in myogenic cells from aged mice results in a significant increase in myogenic differentiation, and its forced expression in those from young mice results in its drastic inhibition.
The results indicate the involvement of Wnt1 and Fzd1 in the pathogenesis and development of amyotrophic lateral sclerosis.
results indicate that frizzled homolog 1(Drosophila)(Fzd1) is required for normal female fertility and may act in part to regulate oocyte maturation and cumulus cell function
Wnt/Fzd signaling is involved in balancing the inflammatory response to microbial stimulation of innate immune cells of vertebrate origin
Frizzled signaling is involved in diverse tissue closure processes, defects in which account for some of the most common congenital anomalies.
Indicate that myofibroblast migration and differentiation are modulated via Wnt/Fzd signalling.
Fz-1 is expressed at distinct stages of follicular development.
Direct interaction of Frizzled-1, -2, -4, and -7 with PDZ domains of PSD-95. "FZ-2, Fz-4, Fz-7"
Frizzled-1 is an antagonist of the canonical Wnt/beta-catenin signaling pathway
Data demonstrate that Wnt7b signals through Fzd1 and -10 and LRP5 and implicate these Wnt coreceptors in the regulation of lung airway and vascular development.
Fzd1 transcription increased during pulmonary fibrosis in mice.
Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK- 3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Activated by Wnt3A, Wnt3, Wnt1 and to a lesser extent Wnt2, but not by Wnt4, Wnt5A, Wnt5B, Wnt6, Wnt7A or Wnt7B.
, frizzled 1
, frizzled 1, seven transmembrane spanning receptor
, frizzled homolog 1
, Wnt receptor
, frizzled, Drosophila, homolog of, 1
, 7-transmembrane protein frizzled-1
, Drosophila polarity gene (frizzled) homologue
, Drosophila polarity gene homolog 1
, 7-transmembrane receptor frizzled-1