Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all synonyms
Select your origin of interest
Results identified an interaction between PLCD3 and FLOT2 (show FLOT2 Proteins). Inhibition of PLCD3 expression impaired the malignant potential of nasopharyngeal carcinoma (NPC (show NPC1 Proteins)) cells, by restraining its growth, proliferation, mobility and migration. This study demonstrated that PLCD3 may be an oncogenic protein in NPC (show NPC1 Proteins) and that it plays an important role in the progression of NPC (show NPC1 Proteins) partially by interacting with Flot2 (show FLOT2 Proteins).
In mo (show PLCD1 Proteins)use, Plcd1 and Plcd3 may act together in murine hair follicles.
Data are consistent with the idea that phospholipase C (show PLC Proteins) d1 and d3 isoforms support the growth and migration of normal and neoplastic mammary epithelial cells in vitro.
Plcd1 (show PLCD1 Proteins) and Plcd3 have synergistic effects on the murine hair follicle in specific regions of the body surface.
These results indicate that PLCdelta3 could participate in stability of microvilli structure via regulating and anchoring of Myo6 (show MYO6 Proteins) to plasma membrane.
PLCdelta3 negatively regulates RhoA (show RHOA Proteins) expression, inhibits RhoA (show RHOA Proteins)/Rho kinase (show ROCK2 Proteins) signaling, and thereby promotes neurite extension.
double disruption of PLCd1 (show PLCD1 Proteins) and PLCd3 results in embryonic lethality because of insufficient vasculariztion of the placenta.
This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4,5-bisphosphate to generate the second messengers diacylglycerol and inositol 1,4,5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids.
phospholipase C delta 3
, phospholipase C, delta 3
, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3
, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-3
, PLC delta3
, phosphoinositide phospholipase C-delta-3
, phospholipase C-delta-3