Browse our Phospholipase C delta 3 Proteins (PLCd3)

Full name:: Phospholipase C delta 3 Proteins (PLCd3)

On www.antibodies-online.com are 5 Phospholipase C delta 3 (PLCd3) Proteins from 4 different suppliers available. Additionally we are shipping Phospholipase C delta 3 Antibodies (33) and and many more products for this protein. A total of 40 Phospholipase C delta 3 products are currently listed.

Synonyms:: 2610205J15Rik, mKIAA1964

list all proteins	Gene Name	GeneID	UniProt
	PLCd3	113026	Q8N3E9
	PLCd3	72469	Q8K2J0
Rat PLCd3	PLCd3	287745
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Phospholipase C delta 3 Proteins (PLCd3) by Origin

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Relevant Pathways for Phospholipase C delta 3 Proteins

WNT Signaling

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More Proteins for Phospholipase C delta 3 Interaction Partners

Human Phospholipase C delta 3 (PLCd3) interaction partners

Results identified an interaction between PLCD3 and FLOT2 (show FLOT2 Proteins). Inhibition of PLCD3 expression impaired the malignant potential of nasopharyngeal carcinoma (NPC (show NPC1 Proteins)) cells, by restraining its growth, proliferation, mobility and migration. This study demonstrated that PLCD3 may be an oncogenic protein in NPC (show NPC1 Proteins) and that it plays an important role in the progression of NPC (show NPC1 Proteins) partially by interacting with Flot2 (show FLOT2 Proteins).
In mo (show PLCD1 Proteins)use, Plcd1 and Plcd3 may act together in murine hair follicles.
Data are consistent with the idea that phospholipase C (show PLC Proteins) d1 and d3 isoforms support the growth and migration of normal and neoplastic mammary epithelial cells in vitro.

Mouse (Murine) Phospholipase C delta 3 (PLCd3) interaction partners

Plcd1 (show PLCD1 Proteins) and Plcd3 have synergistic effects on the murine hair follicle in specific regions of the body surface.
These results indicate that PLCdelta3 could participate in stability of microvilli structure via regulating and anchoring of Myo6 (show MYO6 Proteins) to plasma membrane.
PLCdelta3 negatively regulates RhoA (show RHOA Proteins) expression, inhibits RhoA (show RHOA Proteins)/Rho kinase (show ROCK2 Proteins) signaling, and thereby promotes neurite extension.
double disruption of PLCd1 (show PLCD1 Proteins) and PLCd3 results in embryonic lethality because of insufficient vasculariztion of the placenta.

Phospholipase C delta 3 (PLCd3) Protein Profile

Protein Summary

This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4,5-bisphosphate to generate the second messengers diacylglycerol and inositol 1,4,5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids.

Alternative names and synonyms associated with Phospholipase C delta 3 (PLCd3)

phospholipase C delta 3 (PLCD3)
phospholipase C, delta 3 (Plcd3)

2610205J15Rik protein
mKIAA1964 protein

Protein level used designations for PLCd3

phospholipase C delta 3 , phospholipase C, delta 3 , 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 , 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-3 , PLC delta3 , PLC-delta-3 , phosphoinositide phospholipase C-delta-3 , phospholipase C-delta-3

GENE ID	SPECIES
468279	Pan troglodytes
100352032	Oryctolagus cuniculus
113026	Homo sapiens
72469	Mus musculus
287745	Rattus norvegicus

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