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YWHAB Products

(14-3-3 alpha + beta (YWHAB))
This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008].

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Featured YWHAB Categories

YWHAB Antibodies

High quality antibodies with extensive validation data.

YWHAB ELISA Kits

Reliable ELISA kits for a wide range of species.

YWHAB Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended YWHAB Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, FACS, ICC, IHC, WB
Validations
  • (10)
Cat. No. ABIN5542549
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application IF, IHC, IP, WB
Validations
  • (8)
Cat. No. ABIN3021285
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ICC, IF, IHC (p), WB
Validations
  • (5)
Cat. No. ABIN2856888
Quantity 100 μL
Datasheet Datasheet

Recommended YWHAB ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6975776
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6971014
Quantity 96 tests
Datasheet Datasheet
Reactivity Monkey
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1770939
Quantity 96 tests
Datasheet Datasheet

Recommended YWHAB Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN934969
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3087995
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3128381
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our YWHAB products

Tang, Lv, Sun, Han, Zhou: "14-3-3β Promotes Migration and Invasion of Human Hepatocellular Carcinoma Cells by Modulating Expression of MMP2 and MMP9 through PI3K/Akt/NF-κB Pathway." in: PLoS ONE, Vol. 11, Issue 1, pp. e0146070, (2016) (PubMed).

Dowling, Hughes, Larkin, Meiller, Henry, Meleady, Lynch, Pardini, Naccarati, Levy, Vodicka, Neary, Clynes: "Elevated levels of 14-3-3 proteins, serotonin, gamma enolase and pyruvate kinase identified in clinical samples from patients diagnosed with colorectal cancer." in: Clinica chimica acta; international journal of clinical chemistry, Vol. 441C, pp. 133-141, (2015) (PubMed).

Yang, Thein, Wang, Bi, Ericksen, Xu, Han: "BSCL2/seipin regulates adipogenesis through actin cytoskeleton remodelling." in: Human molecular genetics, Vol. 23, Issue 2, pp. 502-13, (2013) (PubMed).

Minamida, Iwamura, Kodera, Kawashima, Tabata, Matsumoto, Fujita, Satoh, Maeda, Baba: "14-3-3 protein beta/alpha as a urinary biomarker for renal cell carcinoma: proteomic analysis of cyst fluid." in: Analytical and bioanalytical chemistry, Vol. 401, Issue 1, pp. 245-52, (2011) (PubMed).

ODwyer, Ralton, OShea, Murray: "The proteomics of colorectal cancer: identification of a protein signature associated with prognosis." in: PLoS ONE, Vol. 6, Issue 11, pp. e27718, (2011) (PubMed).

Karasawa, Wang, David, Steyger: "CLIMP-63 is a gentamicin-binding protein that is involved in drug-induced cytotoxicity." in: Cell death & disease, Vol. 1, pp. e102, (2011) (PubMed).

Yue, Song, Ma, Feng, Guan, Wu, Yang, Jiang, Liu, Cui, Guo: "Effects of triterpenes from Ganoderma lucidum on protein expression profile of HeLa cells." in: Phytomedicine : international journal of phytotherapy and phytopharmacology, Vol. 17, Issue 8-9, pp. 606-13, (2010) (PubMed).

Aitken: "14-3-3 proteins: a historic overview." in: Seminars in cancer biology, Vol. 16, Issue 3, pp. 162-72, (2006) (PubMed).

Rodriguez, Guan: "14-3-3 regulation of cell spreading and migration requires a functional amphipathic groove." in: Journal of cellular physiology, Vol. 202, Issue 1, pp. 285-94, (2004) (PubMed).

Berg, Holzmann, Riess: "14-3-3 proteins in the nervous system." in: Nature reviews. Neuroscience, Vol. 4, Issue 9, pp. 752-62, (2003) (PubMed).

Synonyms and alternative names related to YWHAB

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta (YWHAB), tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide (Ywhab), tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b (ywhabb), tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta (Ywhab), tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta S homeolog (ywhab.S), tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta L homeolog (ywhab.L), tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a (ywhaba), tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta (Ywhab), 14-3-3beta, 1300003C17Rik, fb80c08, fk41f08, GW128, HS1, KCIP-1, wu:fb22g04, wu:fb80c08, wu:fd11d01, wu:fk41f08, wu:fr86a12, YWHAA, ywhab, ywhab1, ywhab2, zgc:64092

Protein level used designations for YWHAB

  • 14-3-3 alpha
  • 14-3-3 protein beta/alpha
  • brain protein 14-3-3, beta isoform
  • protein 1054
  • protein kinase C inhibitor protein 1
  • protein kinase C inhibitor protein-1
  • tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, alpha polypeptide
  • 14-3-3 protein beta
  • KCIP-1
  • tyrosine 3/tryptophan 5 -monooxygenase activation protein, beta polypeptide
  • 14-3-3 protein beta/alpha-2
  • 14-3-3 protein beta/alpha-B
  • tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 2
  • 14-3-3 protein beta-subtype
  • 3-monooxygenase/tryptophan 5 monooxygenase activation protein beta polypeptide
  • prepronerve growth factor RNH-1
  • tryosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta polypeptide
  • tryosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
  • tyrosine 3-monooxgenase/tryptophan 5 monooxgenase activation protein beta polypeptide
  • tyrosine 3-monooxgenase/tryptophan 5 monooxgenase activation protein, beta polypeptide
  • tyrosine 3-monooxgenase/tryptophan 5-monooxgenase activation protein, beta polypeptide
  • tyrosine 3/tryptophan 5 -monooxygenase activation protein beta polypeptide
  • 14-3-3 beta
  • 14-3-3 protein beta/alpha-A
  • 14-3-3-like protein
  • 14-3-3 protein beta/alpha-1
  • tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 1
  • tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
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