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anti-Activin A Receptor, Type IIA (ACVR2A) Antibodies

ACVR2A encodes activin A type II receptor. Additionally we are shipping Activin Receptor Type IIA Proteins (27) and Activin Receptor Type IIA Kits (17) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ACVR2A 92 P27037
ACVR2A 29263 P38444
ACVR2A 11480 P27038
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Top anti-Activin Receptor Type IIA Antibodies at

Showing 10 out of 100 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human cancer tissue reacted with ... (LEFT)Western blot analysis of anti-ACVR2A Antibody (N-term) in mouse ... 0.4 mL Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-ACVR2A Antibody (N-term) (ABIN391160) in... Western blot analysis of ACVR2A (arrow) using rabbit polyclonal ACVR2A... 400 μL Log in to see 10 to 11 Days
Human Mouse Un-conjugated IP, WB   0.1 mg Log in to see 10 to 12 Days
Mouse Rabbit Un-conjugated WB Mouse Acvr2a Antibody (N-term)  western blot analysis in mouse kidney ... 400 μL Log in to see 10 to 11 Days
Human Rabbit Un-conjugated WB Western blot (WB) analyzes of ACTR-IIA antibody in extracts from rat k... 0.1 mg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Anti ARIP2... Lane 1: mouse testis lysates Lane 2: mouse brain lysates probed with A... 100 μL Log in to see 3 to 7 Days
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
Human Mouse APC FACS   100 Tests Log in to see 8 to 10 Days
Human Rabbit Un-conjugated IHC, ELISA, WB The ACTR-IIA Antibody is used in Western blot to detect ACTR-IIA in mo... 0.1 mg Log in to see 2 to 6 Days
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days

ACVR2A Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Activin Receptor Type IIA Antibodies

  1. Human Polyclonal Activin Receptor Type IIA Primary Antibody for EIA, IHC (p) - ABIN359228 : Jung, Doctolero, Tajima, Nguyen, Keku, Sandler, Carethers: Loss of activin receptor type 2 protein expression in microsatellite unstable colon cancers. in Gastroenterology 2004 (PubMed)
    Show all 5 references for ABIN359228

  2. Human Polyclonal Activin Receptor Type IIA Primary Antibody for IHC (p), WB - ABIN391160 : Olaru, Mori, Yin, Wang, Kimos, Perry, Xu, Sato, Selaru, Deacu, Sterian, Shibata, Abraham, Meltzer: Loss of heterozygosity and mutational analyses of the ACTRII gene locus in human colorectal tumors. in Laboratory investigation; a journal of technical methods and pathology 2003 (PubMed)
    Show all 3 references for ABIN391160

  3. Human Monoclonal Activin Receptor Type IIA Primary Antibody for IP, WB - ABIN180386 : McCarthy, Bicknell: Activin-A binds to a heterotrimeric receptor complex on the vascular endothelial cell surface. Evidence for a type 3 activin receptor. in The Journal of biological chemistry 1994 (PubMed)
    Show all 2 references for ABIN180386

More Antibodies against Activin Receptor Type IIA Interaction Partners

Human Activin A Receptor, Type IIA (ACVR2A) interaction partners

  1. Data suggest ALK1 (show ACVRL1 Antibodies) and ACVR2A/ACVR2B (show ACVR2B Antibodies), acting as BMP9 (show GDF2 Antibodies) co-receptors, rearrange pro-domains of BMP9 (show GDF2 Antibodies)--pro-domain dimer complex leading to displacement of pro-domains after receptor binding, release of mature non-dimer BPM9, and activation of signaling.

  2. Activin A (show INHBA Antibodies) inhibited signaling by BMP-6 (show BMP6 Antibodies) and BMP-9 (show GDF2 Antibodies) by competing for type 2 receptors ACVR2A and ACVR2B (show ACVR2B Antibodies).

  3. Data suggest that an SNP in promoter region of ACVR2A (rs1424954, the pre-eclampsia susceptibility allele) down-regulates 1) expression of ACVR2A in trophoblasts and 2) signal transduction in response to excess activin-A (show INHBA Antibodies) (as seen in pre-eclampsia).

  4. Adenomyotic tissues express high levels of myostatin (show MSTN Antibodies), follistatin (show FST Antibodies), and activin (show Actbeta Antibodies) type II receptors.

  5. The gene ACVR2A was associated with the more severe early onset preeclampsia.

  6. For ACVR2A SNPs (rs10497025, rs1128919, rs13430086), no statistically significant difference was found between preeclampsia and control groups in terms of genotype and allele frequencies.

  7. ACVR2A was identified as a subnetwork component in functional association network analysis.

  8. ACVR2A showed statistically significant differential dose-expression relationship.

  9. ACVR2A interaction with Nodal and ADMP regulates head development from the 'organizer', a restricted group of cells in the embryo.

  10. This is the first report on the function of miR (show MLXIP Antibodies)-195 in human placental trophoblast cells which reveals an invasion-promoting effect of the small RNA via repressing ActRIIA.

Cow (Bovine) Activin A Receptor, Type IIA (ACVR2A) interaction partners

  1. This genome-wide association study identified variants in the upstream region of ACVR2A, which were associated with female fertility in Japanese Black cattle.

Zebrafish Activin A Receptor, Type IIA (ACVR2A) interaction partners

  1. Roles in hindbrain and neural crest cell (NCC) patterning, in NCC derived pharyngeal arch cartilage and joint formation, and in tooth development.

Mouse (Murine) Activin A Receptor, Type IIA (ACVR2A) interaction partners

  1. Our study shows that a miR (show MLXIP Antibodies)-590/Acvr2a/Rad51b (show Rad51B Antibodies) signaling axis ensures the stabilization of mESCs by balancing DNA damage repair and rapid proliferation during self-renewal.

  2. Bmpr2 (show BMPR2 Antibodies) and Acvr2a normally play cell-type-specific, necessary roles in organelle biogenesis and the shutdown of developmental programs and cell division.

  3. Acvr2a is a Th17 specific gene making Th17 cells distinct from other helper T cells, Th1 (show HAND1 Antibodies), Th2, and Treg.

  4. stimulates expression of APRIL via the Smad3 (show SMAD3 Antibodies) and ERK (show EPHB2 Antibodies)/CREB (show CREB1 Antibodies) pathways in macrophages

  5. Results demonstrated that BMPRII (show BMPR2 Antibodies) and ActRII are the functional type II TGF-beta (show TGFB1 Antibodies) receptors in BMP-9 (show GDF2 Antibodies)-induced osteogenic differentiation of C3H10T1/2 cells.

  6. The coordinated activity of ActRIIA and BMPRII (show BMPR2 Antibodies) receptor subunits selectively mediates the chemotactic response to BMP7 (show BMP7 Antibodies).

  7. Activin (show Actbeta Antibodies) type IIB(ActRIIB (show ACVR2B Antibodies)) and its subfamily receptor, Activin (show Actbeta Antibodies) type IIA (ActRIIA), cooperatively mediate the Gdf11 (show GDF11 Antibodies) signal in patterning the axial vertebrae

  8. analysis of expression and cellular compartmentalization of the activin (show Actbeta Antibodies) receptors ActRIIA, ActRIIB (show ACVR2B Antibodies) and ActRIB (show ACVR1B Antibodies), the inhibin co-receptor (betaglycan (show TGFBR3 Antibodies)), and activin (show Actbeta Antibodies) signaling proteins Smads 2, 3 and 4, and growth regulatory role during lactation

  9. Data suggest that activin receptor II signaling is critical only for follicle-stimulating hormone homeostasis and not for gonadotrophin-releasing hormone (GnRH)biosynthesis or induction of pituitary GnRH receptor expression.

  10. Overexpression of ARIP2 (show SYNJ2BP Antibodies) enhances endocytosis of ActRIIAs; data indicate that ARIP2 (show SYNJ2BP Antibodies) is a novel factor regulating cell surface ActRIIA expression and activin (show Actbeta Antibodies) function.

Activin Receptor Type IIA (ACVR2A) Antigen Profile

Protein Summary

This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling\; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.

Gene names and symbols associated with ACVR2A

  • activin A receptor, type IIA (ACVR2A) antibody
  • activin A receptor, type IIA (acvr2a) antibody
  • activin A receptor, type IIA (LOC100224301) antibody
  • activin A receptor, type IIA (Acvr2a) antibody
  • activin A receptor, type IIAa (acvr2aa) antibody
  • activin receptor IIA (Acvr2a) antibody
  • actr2a antibody
  • ACTRII antibody
  • ActrIIa antibody
  • Acvr2 antibody
  • acvr2a antibody
  • rActR-II antibody
  • TactrII antibody
  • wu:fa02e10 antibody
  • XSTK9 antibody

Protein level used designations for ACVR2A

activin receptor IIA , activin receptor type-2A , activin A receptor, type IIA , ACTR-IIA , activin receptor type IIA , type II activin receptor , activin A receptor, type II , activin receptor, type IIA , ACTRIIA , activin receptor type II , activin type 2 receptor , activin receptor IIa , etID22865.9

397282 Sus scrofa
476140 Canis lupus familiaris
100216172 Xenopus (Silurana) tropicalis
100224301 Taeniopygia guttata
100583170 Nomascus leucogenys
92 Homo sapiens
29263 Rattus norvegicus
281598 Bos taurus
396324 Gallus gallus
443304 Ovis aries
399283 Xenopus laevis
553359 Danio rerio
11480 Mus musculus
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