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anti-Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) Antibodies

This protein belongs to the aldehyde dehydrogenase family of proteins. Additionally we are shipping Aldehyde Dehydrogenase 2 Family (Mitochondrial) Kits (20) and Aldehyde Dehydrogenase 2 Family (Mitochondrial) Proteins (15) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ALDH2 217 P05091
ALDH2 29539 P11884
ALDH2 11669 P47738
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Top anti-Aldehyde Dehydrogenase 2 Family (Mitochondrial) Antibodies at antibodies-online.com

Showing 10 out of 143 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of ALDH2 (arrow) using rabbit polyclonal ALDH2 Antibody (Center) (ABIN388202).293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the ALDH2 gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ALDH2 antibody (Center) (ABIN388202), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IF, WB Western blot analysis of ALDH2 (arrow) using rabbit polyclonal ALDH2 Antibody (N-term) 56381 Da (ABIN388201). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the ALDH2 gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ALDH2 antibody (N-term) (ABIN388201), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Cow Goat Un-conjugated EIA, WB AP20182PU-N (1.5 µg/ml) as the reporter with a capture Rabbit antibody (2.5 µg/ml). Western blot analysis: ALDH2 antibody staining of Mouse Liver lysate at 0.03 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Mouse Un-conjugated FACS, IF, IHC (p), WB Western blot analysis of ALDH2 monoclonal antibody  in HepG2 cell line lysates (35ug/lane). ALDH2 (arrow) was detected using the purified mab.(4ug/ml) ALDH2 Monoclonal Antibody  immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.  This data demonstrates the use of the ALDH2 Monoclonal Antibody for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated ICC, FACS, IHC, ELISA, WB 0.1 mg Log in to see 3 to 4 Days
$430.10
Details
Human Mouse Un-conjugated FACS, IF Anti-ALDH2 mouse monoclonal antibody (ABIN2452752) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ALDH2 (RC200505). Immunofluorescent staining of HepG2 cells using anti-ALDH2 mouse monoclonal antibody (ABIN2452752). 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$283.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB ALDH2 Antibody (ABIN1881053) flow cytometry analysis of MDA-MB231 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. ALDH2 Antibody (ABIN1881053) flow cytometry analysis of MDA-MB231 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details

ALDH2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Rat (Rattus)
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Mouse (Murine)
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Top referenced anti-Aldehyde Dehydrogenase 2 Family (Mitochondrial) Antibodies

  1. Human Monoclonal ALDH2 Primary Antibody for FACS, IF - ABIN658993 : Yang, Yokoyama, Yokoyama, Huang, Wu, Shao, Niu, Wang, Liu, Zhou, Yang: Relationship between genetic polymorphisms of ALDH2 and ADH1B and esophageal cancer risk: a meta-analysis. in World journal of gastroenterology : WJG 2010 (PubMed)
    Show all 5 references for ABIN658993

  2. Human Polyclonal ALDH2 Primary Antibody for FACS, IHC (p) - ABIN1881053 : Guo, Wang, Liu, Chen, Qi, Guo: Genetic polymorphisms in cytochrome P4502E1, alcohol and aldehyde dehydrogenases and the risk of esophageal squamous cell carcinoma in Gansu Chinese males. in World journal of gastroenterology : WJG 2008 (PubMed)
    Show all 3 references for ABIN1881053

  3. Human Polyclonal ALDH2 Primary Antibody for EIA, IHC (p) - ABIN356918 : Yoshida: Molecular genetics of human aldehyde dehydrogenase. in Pharmacogenetics 1993 (PubMed)
    Show all 3 references for ABIN356918

  4. Human Monoclonal ALDH2 Primary Antibody for ICC, FACS - ABIN1724796 : Zhang, Gong, Zhang, Li, Hu: Effect of mitochondrial aldehyde dehydrogenase-2 genotype on cardioprotection in patients with congenital heart disease. in European heart journal 2012 (PubMed)
    Show all 2 references for ABIN1724796

  5. Human Monoclonal ALDH2 Primary Antibody for FACS, IF - ABIN2452752 : Qiang, Xiao, Su, Wu, Tong, Liu, He: A novel mechanism for endogenous formaldehyde elevation in SAMP8 mouse. in Journal of Alzheimer's disease : JAD 2014 (PubMed)

  6. Cow (Bovine) Polyclonal ALDH2 Primary Antibody for EIA, WB - ABIN498080 : Kimura, Sawayama, Matsushita, Higuchi, Kashima: Association between personality traits and ALDH2 polymorphism in Japanese male alcoholics. in Alcoholism, clinical and experimental research 2009 (PubMed)

More Antibodies against Aldehyde Dehydrogenase 2 Family (Mitochondrial) Interaction Partners

Rabbit Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) interaction partners

  1. ALDH-2 is involved in the remote ischemic preconditioning pathway.

Human Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) interaction partners

  1. ALDH2 polymorphism has a significant impact on human health[review]

  2. population-level instrumental variable estimation (utilizing interaction of rs671 in ALDH2 and sex as an instrument) strengthens causal inference regarding the largely adverse influence of alcohol intake on cardiovascular health in an Asian population.

  3. the combination of genotypes ADH2 * 2, CYP2E1 (show CYP2E1 Antibodies) * 1 combined with genotype homozygous ALDH2 * 1 found in this study could be leading to the population to a potential risk to alcoholism.

  4. Tthe ALDH2*2 allele is associated with a risk for nonalcoholic fatty liver disease in relation to an elevated gamma-glutamyl transferase level.

  5. The results show that the variant rs671 in ALDH2 is associated with an increased risk of coronary artery disease in southern Chinese, while not in northern Chinese.

  6. The genotype frequencies of ALDH2 polymorphisms were 62.6, 32.7, and 4.7% for *1/*1, *1/*2, and *2/*2, respectively. Systolic blood pressure and diastolic blood pressure in the *1/*2 or *2/*2 group were significantly lower than those in the *1/*1 group.

  7. suggested that having the ADH1B (show ADH1B Antibodies)*2/*2 genotype caused a positive reaction in subjects with the ALDH2*1/*1 genotype

  8. Evidence suggests that ALDH2 Glu504Lys SNP is a potential candidate genetic risk factor for a variety of chronic diseases such as cardiovascular disease, cancer, and late-onset Alzheimer's disease.

  9. many types of cancers are associated with ALDH2 mutation, such as hepatocellular carcinoma, gastric cancer, and colon cancer; there may be a connection between the single nucleotide polymorphism of ALDH2 rs671 and these cancers

  10. patients with the G-allele displayed retarded methylation readjustment and no change in ALDH2 protein levels.

Cow (Bovine) Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) interaction partners

  1. analysis of bioactivation of nitroglycerin by purified mitochondrial and cytosolic aldehyde dehydrogenases ALDH1 (show ALDH1A1 Antibodies) and ALDH2

Mouse (Murine) Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) interaction partners

  1. Our findings provide new insight into the preventive role of oesophageal ALDH2 against acetaldehyde-derived DNA damage.

  2. High concentrations of ETBE might result in reproductive toxicity in mice with normal active ALDH2, while low active/inactive ALDH2 significantly enhanced the ETBE-induced reproductive toxicity in mice.

  3. ALDH2 deficiency enhances ethanol-induced disruption of intestinal epithelial tight junctions.

  4. In mice lacking ALDH2, there would be increases in 4-hydroxynonenal and the appearance of Alzheimer's disease-like pathological changes.

  5. Mitochondrial aldehyde dehydrogenase 2 plays protective roles in heart failure after myocardial infarction via suppression of the cytosolic JNK (show MAPK8 Antibodies)/p53 (show TP53 Antibodies) pathway in mice.

  6. ALDH2 functions as a tumor suppressor by maintaining genomic stability in the liver, and the common human ALDH2 variant would present a significant risk factor for hepatocarcinogenesis.

  7. ALDH2 activation, Alda-1, inhibited atherosclerosis and attenuated NAFLD (show TSC2 Antibodies) in apoE (show APOE Antibodies)(-/-) mice.

  8. Findings suggest that miR (show MLXIP Antibodies)-28 promotes myocardial ischemia through the inhibition of ALDH2 expression in mus (show TRPV6 Antibodies).

  9. Rutin increased ALDH2 expression, while daidzin reversed this beneficial effect. Thus, this study demonstrates rutin protects HT22 cells against ethanol-induced neurotoxicity by increasing ALDH2 activity.

  10. Alda-89 reduced acetaldehyde-induced behavioral impairment by causing a rapid reduction in blood ethanol and acetaldehyde levels after acute ethanol intoxication in both wild-type and ALDH2-deficient, ALDH2*1/*2, heterozygotic knock-in mice

Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) Antigen Profile

Protein Summary

This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with ALDH2

  • aldehyde dehydrogenase 2, tandem duplicate 1 (aldh2.1) antibody
  • aldehyde dehydrogenase 2 family (mitochondrial) (aldh2) antibody
  • aldehyde dehydrogenase 2 family (mitochondrial) (ALDH2) antibody
  • aldehyde dehydrogenase2 (aldh2) antibody
  • aldehyde dehydrogenase, mitochondrial-like (ALDH2) antibody
  • aldehyde dehydrogenase (aldH2) antibody
  • aldehyde dehydrogenase (NAD(+)) (aldH2) antibody
  • aldehyde dehydrogenase 2 family (mitochondrial) (LOC100217978) antibody
  • aldehyde dehydrogenase 2 family (mitochondrial) (Aldh2) antibody
  • aldehyde dehydrogenase 2, mitochondrial (Aldh2) antibody
  • Ahd-5 antibody
  • Ahd5 antibody
  • ALDH-E2 antibody
  • aldh2 antibody
  • aldh2a antibody
  • ALDHI antibody
  • ALDM antibody
  • MGC80785 antibody
  • rf2b antibody
  • zgc:63786 antibody

Protein level used designations for ALDH2

aldehyde dehydrogenase 2 , aldehyde dehydrogenase 2 family (mitochondrial) , aldehyde dehydrogenase 2 family (mitochondrial)a , aldehyde dehydrogenase 2.1 , mitochondrial aldehyde dehydrogenase 2 , ALDH2B6 , mitochondrial aldehyde dehydrogenase RF2B , aldehyde dehydrogenase , aldehyde dehydrogenase (NAD(+)) , ALDH class 2 , ALDH-E2 , aldehyde dehydrogenase, mitochondrial , aldehyde dehydrogenase, mitochondrial-like , acetaldehyde dehydrogenase 2 , liver mitochondrial ALDH , nucleus-encoded mitochondrial aldehyde dehydrogenase 2 , ALDH1 , aldehyde dehydrogenase 2, mitochondrial , mitochondrial aldehyde dehydrogenase , ALDHI , AHD-M1

GENE ID SPECIES
393462 Danio rerio
446857 Xenopus laevis
448267 Xenopus (Silurana) tropicalis
452252 Pan troglodytes
542567 Zea mays
713451 Macaca mulatta
4226489 Rhodococcus jostii RHA1
5776113 Staphylococcus aureus subsp. aureus USA300_TCH1516
5952690 Halobacterium salinarum R1
9005267 Rhodobacter capsulatus SB 1003
100171596 Pongo abelii
100217978 Taeniopygia guttata
100338523 Oryctolagus cuniculus
100388478 Callithrix jacchus
217 Homo sapiens
29539 Rattus norvegicus
610941 Canis lupus familiaris
733685 Sus scrofa
508629 Bos taurus
416880 Gallus gallus
11669 Mus musculus
Selected quality suppliers for anti-Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) Antibodies
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