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anti-Arrestin, beta 2 (ARRB2) Antibodies

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Additionally we are shipping Arrestin 3 Kits (37) and Arrestin 3 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ARRB2 409 P32121
ARRB2 25388 P29067
ARRB2 216869 Q91YI4
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Top anti-Arrestin 3 Antibodies at antibodies-online.com

Showing 10 out of 82 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated IHC, WB Sample Type: HepG2 cell lysateAntibody concentration: 1.0 ug/mlGel concentration: 12%. IHC Information: Human skin.  Antibody concentration: 4.0-8.0 ug/ml. 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN185395 (0.03µg/ml) staining of Human Spleen lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Goat Un-conjugated EIA, IHC (p), IP, WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Mouse Un-conjugated WB Western Blot analysis of ARRB2 expression in transfected 293T cell line by ARRB2 monoclonal antibody (M01), clone 3G1. Lane 1: ARRB2 transfected lysate(46 KDa). Lane 2: Non-transfected lysate. Immunoperoxidase of monoclonal antibody to ARRB2 on formalin-fixed paraffin-embedded human tonsil (antibody concentration 3 µg/mL). 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to ARRB2 on HeLa cell (antibody concentration 10 µg/mL). ARRB2 monoclonal antibody (M06), clone 4D2 Western Blot analysis of ARRB2 expression in HeLa. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated EIA, IF, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$566.50
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-Beta Arrestin 2 antibody, IHC(P) IHC(P): Human Intestinal Cancer Tissue Anti-Beta Arrestin 2 antibody, Western blotting All lanes: Anti ARRB2  at 0.5ug/ml Lane 1: HELA Whole Cell Lysate at 40ug Lane 2: Rat Skeletal Muscle Tissue Lysate at 50ug Predicted bind size: 46KD Observed bind size: 46KD 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-ARRB2 antibody IHC staining of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1100232 dilution 5 ug/ml. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC, WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Goat Un-conjugated ELISA, WB 100 μg Log in to see 8 to 10 Days
$595.83
Details

ARRB2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,
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Rat (Rattus)
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Mouse (Murine)
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Top referenced anti-Arrestin 3 Antibodies

  1. Human Monoclonal Arrestin 3 Primary Antibody for WB - ABIN393334 : Oneda, Crettol, Bochud, Besson, Croquette-Krokar, Hämmig, Monnat, Preisig, Eap: β-Arrestin2 influences the response to methadone in opioid-dependent patients. in The pharmacogenomics journal 2011 (PubMed)
    Show all 5 references for ABIN393334

  2. Human Monoclonal Arrestin 3 Primary Antibody for IF, WB - ABIN393344 : Li, Sun, LeSage, Zhang, Liang, Chen, Hanley, He, Sun, Yin: β-arrestin 2 regulates Toll-like receptor 4-mediated apoptotic signalling through glycogen synthase kinase-3β. in Immunology 2010 (PubMed)
    Show all 5 references for ABIN393344

  3. Human Polyclonal Arrestin 3 Primary Antibody for IHC, ELISA - ABIN185395 : Lefkowitz, Shenoy: Transduction of receptor signals by beta-arrestins. in Science (New York, N.Y.) 2005 (PubMed)
    Show all 3 references for ABIN185395

  4. Human Polyclonal Arrestin 3 Primary Antibody for EIA, IHC (p) - ABIN374557 : Zakrzewicz, Krasteva, Wilhelm, Dietrich, Wilker, Padberg, Wygrecka, Grau: Reduced expression of arrestin beta 2 by graft monocytes during acute rejection of rat kidneys. in Immunobiology 2011 (PubMed)
    Show all 3 references for ABIN374557

  5. Chicken Polyclonal Arrestin 3 Primary Antibody for IHC, WB - ABIN2783190 : Luan, Zhang, Wu, Kang, Pei: Beta-arrestin2 functions as a phosphorylation-regulated suppressor of UV-induced NF-kappaB activation. in The EMBO journal 2005 (PubMed)

More Antibodies against Arrestin 3 Interaction Partners

Human Arrestin, beta 2 (ARRB2) interaction partners

  1. Substance P (show TAC1 Antibodies) enhances tissue factor (show F3 Antibodies) release from granulocyte-macrophage colony-stimulating factor (show CSF2 Antibodies)-dependent macrophages via the p22phox (show CYBA Antibodies)/beta-arrestin 2/Rho A (show RHOA Antibodies) signaling pathway.

  2. beta-arrestins regulate oxidative stress in a Nox4 (show NOX4 Antibodies)-dependent manner and increase fibrosis in heart failure.

  3. Results demonstrate that betaArr2 signaling may be an important pathway for TAAR1 (show TAAR1 Antibodies) function and that the activation of the TAAR1 (show TAAR1 Antibodies)-D2R (show DRD2 Antibodies) complex negatively modulates GSK3b (show GSK3b Antibodies) signaling

  4. Role for engagement of BARR2 by the transactivated EGFR (show EGFR Antibodies) in agonist-specific regulation of delta receptor activation of ERK1/2 (show MAPK1/3 Antibodies)

  5. Data suggest that thrombin (show F2 Antibodies) can directly activate PAR2 (show F2RL1 Antibodies) vasorelaxation, signal transduction (stimulating both calcium and MAP kinase (show MAPK1 Antibodies) responses), and triggering beta-arrestin recruitment (both beta-arrestin 1 (show ARRB1 Antibodies) and 2).

  6. a beta-arrestin signalling cycle that is catalytically activated by the GPCR and energetically coupled to the endocytic machinery

  7. The rare variants in ARRB2 were significantly associated with smoking status.

  8. analysis of the crystal structure of the rhodopsin (show RHO Antibodies)-arrestin (show SAG Antibodies) complex

  9. In this study, we aimed to exploit an in vitro model system of BPH in order to better understand the mechanisms of alpha-AR signaling in prostatic hyperplasia.

  10. interaction of beta-arrestin with GPCRs, and the beta-arrestin conformational changes in real time and in living human cells, using a series of fluorescence resonance energy transfer (FRET)-based beta-arrestin2 biosensors

Cow (Bovine) Arrestin, beta 2 (ARRB2) interaction partners

  1. The fraction of arrestin2 molecules found in clusters larger than 100nm correlates with the magnitude of ligand-induced CCR5 (show CCR5 Antibodies) internalization.

  2. K2A mutations in arrestin-1 (show SAG Antibodies), -2, and -3 significantly reduced their binding to active phosphorhodopsin.

  3. Results reveal that multiple intramolecular interactions coordinately regulate arrestin2 interaction with clathrin, highlighting this interaction as a critical step in regulating receptor trafficking.

Mouse (Murine) Arrestin, beta 2 (ARRB2) interaction partners

  1. [beta]-arrestin2 regulates intestinal mucosal inflammation under both homeostatic and colitic conditions. Its mode of action involves negative regulation of T-cell activation and its requirement for induction of regulatory T cells.

  2. Results suggest that the antipruritic effects of kappa opioid receptor (show OPRK1 Antibodies) agonists may not require betaarrestin2

  3. that pro- and anti-inflammatory activities of beta-arrestin2 are determined by beta-arrestin2 ubiquitination and that changes in USP20 (show USP20 Antibodies) expression and/or activity can therefore regulate inflammatory responses

  4. This shows that mood stabilizers lamotrigine, lithium and valproate can exert behavioral effects in mice by disrupting the beta-arrestin 2-mediated regulation of Akt (show AKT1 Antibodies)/GSK3 (show GSK3b Antibodies) signaling by D2 dopamine receptors.

  5. findings show for the first time that Ang II (show AGT Antibodies) receptor signaling to beta-arrestin regulates ARF6 (show ARF6 Antibodies) activation. These proteins together control receptor endocytosis and ultimately cell migration.

  6. These results reveal that the protective effect of deficiency of Arrb2 is due to loss of negative regulation of Akt (show AKT1 Antibodies).

  7. that Insulin-like growth factor-1 (show IGF1 Antibodies) contributes to the mucosal repair by beta-arrestin2-mediated extracellular signal-regulated kinase signaling in experimental colitis

  8. ARRB2 is not involved in hepatocellular carcinogenesis.

  9. morphine activated JNK2 through an arrestin-independent Src- and PKC-dependent mechanism, whereas fentanyl activated JNK2 through a Src-GRK3/arrestin-2-dependent and PKC-independent mechanism.

  10. Arrb2 is required for potentiation of odorant receptor responses by Chrm3 (show CHRM3 Antibodies).

Xenopus laevis Arrestin, beta 2 (ARRB2) interaction partners

  1. Arrb2 physically interacts with the beta subunit (show POLG Antibodies) of trimeric G-proteins and Dishevelled (show DVL2 Antibodies), the interaction between arrb2 and Dishevelled (show DVL2 Antibodies) is promoted by the beta/gamma subunits of trimeric G-proteins.

Zebrafish Arrestin, beta 2 (ARRB2) interaction partners

  1. results suggest that a functional interaction between beta-arrestin 2 and Smoothened (show SMO Antibodies) may be critical to regulate hedgehog (show SHH Antibodies) signaling in zebrafish development

Arrestin 3 (ARRB2) Antigen Profile

Protein Summary

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ARRB2

  • arrestin, beta 2 (ARRB2) antibody
  • arrestin, beta 2 (arrb2) antibody
  • arrestin, beta 2 (Arrb2) antibody
  • arrestin, beta 2b (arrb2b) antibody
  • AI326910 antibody
  • ARB2 antibody
  • ARR2 antibody
  • arrb2 antibody
  • arrestin antibody
  • AW122872 antibody
  • BARR2 antibody
  • BARRES antibody
  • betaarr2 antibody
  • zgc:64007 antibody

Protein level used designations for ARRB2

arrestin beta 2 , arrestin, beta 2 , arrestin 2 , beta-Arrestin 2 , arrestin beta-2 , beta-arrestin-2 , beta-arrestin-2-like , arrestin 3 , arrestin-3 , beta arr2 , beta-arrestin 2 , ARRB2b2

GENE ID SPECIES
454450 Pan troglodytes
709399 Macaca mulatta
100101741 Xenopus (Silurana) tropicalis
100172117 Pongo abelii
100387113 Callithrix jacchus
100478601 Ailuropoda melanoleuca
100599882 Nomascus leucogenys
409 Homo sapiens
25388 Rattus norvegicus
281638 Bos taurus
216869 Mus musculus
444007 Xenopus laevis
607262 Canis lupus familiaris
100170767 Sus scrofa
100341204 Oryctolagus cuniculus
100072892 Equus caballus
100716149 Cavia porcellus
101112493 Ovis aries
394099 Danio rerio
Selected quality suppliers for anti-Arrestin 3 (ARRB2) Antibodies
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