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The aryl hydrocarbon (Ah) receptor is involved in the induction of several enzymes that participate in xenobiotic metabolism. Additionally we are shipping ARNT Kits (17) and ARNT Proteins (8) and many more products for this protein.
Showing 10 out of 167 products:
Cow (Bovine) Monoclonal ARNT Primary Antibody for ChIP, GS - ABIN151055
Alam, Maizels, Park, Ghaey, Feiger, Chandel, Hunzicker-Dunn et al.: Follicle-stimulating hormone activation of hypoxia-inducible factor-1 by the phosphatidylinositol 3-kinase/AKT/Ras homolog enriched in brain (Rheb)/mammalian target of rapamycin (mTOR) pathway is ... in The Journal of biological chemistry 2004
Show all 87 references for ABIN151055
Amphibian Monoclonal ARNT Primary Antibody for ChIP, GS - ABIN152684
Singh, Wyman, Casado, Garrett, Gasiewicz: Treatment of mice with the Ah receptor agonist and human carcinogen dioxin results in altered numbers and function of hematopoietic stem cells. in Carcinogenesis 2009
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Human Monoclonal ARNT Primary Antibody for IF, WB - ABIN968356
Ambrosini, Nath, Sierra-Honigmann, Flores-Riveros: Transcriptional activation of the human leptin gene in response to hypoxia. Involvement of hypoxia-inducible factor 1. in The Journal of biological chemistry 2002
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Human Monoclonal ARNT Primary Antibody for IF, WB - ABIN968355
Drutel, Kathmann, Heron, Schwartz, Arrang: Cloning and selective expression in brain and kidney of ARNT2 homologous to the Ah receptor nuclear translocator (ARNT). in Biochemical and biophysical research communications 1996
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Human Monoclonal ARNT Primary Antibody for IF, WB - ABIN394250
Jugessur, Shi, Gjessing, Lie, Wilcox, Weinberg, Christensen, Boyles, Daack-Hirsch, Nguyen, Christiansen, Lidral, Murray: Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. in PLoS ONE 2010
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Human Polyclonal ARNT Primary Antibody for IF, WB - ABIN658231
Otsubo, Kanegane, Eguchi, Eguchi-Ishimae, Tamura, Nomura, Abe, Ishii, Miyawaki: ETV6-ARNT fusion in a patient with childhood T lymphoblastic leukemia. in Cancer genetics and cytogenetics 2010
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Human Monoclonal ARNT Primary Antibody for FACS, IF - ABIN2452782
Hao, Bhakti, Peet, Whitelaw: Reciprocal regulation of the basic helix-loop-helix/Per-Arnt-Sim partner proteins, Arnt and Arnt2, during neuronal differentiation. in Nucleic acids research 2013
Human Polyclonal ARNT Primary Antibody for ELISA, WB - ABIN1533680
Hoffman, Reyes, Chu, Sander, Conley, Brooks, Hankinson: Cloning of a factor required for activity of the Ah (dioxin) receptor. in Science (New York, N.Y.) 1991
Morpholino experiments show that knockdown of ARNT1 offers protection from TCCD-induced cardiotoxicity.
The results of this study indicate that ARNT depletion renders tumour cells susceptible to radiation whereas overexpression of this transcription factor confers radioresistance
HIF-1beta might act as a novel cross-link between the HIF and NF-kappaB (show NFKB1 Antibodies) pathways in suppression of angiogenesis by LDL, while proteasome inhibitors might promote angiogenesis by reactivating this signaling cascade under hyperlipidemia.
ARNT Val189Val polymorphism is not associated with endometriosis in Asians.
HIF1 (show HIF1A Antibodies) regulates claudin-1 (show CLDN7 Antibodies) in intestinal epithelium. This regulation is important for intestinal epithelial tight junction integrity.
Down-regulation of ARNT promotes colorectal cancer metastasis by activating the fibronectin (show FN1 Antibodies)/integrin beta1/FAK (show PTK2 Antibodies) axis.
AhR (show AHR Antibodies)/ARNT activation and overexpression of BCL6 (show BCL6 Antibodies) are collectively responsible for differential expression of more than 100 genes in diffuse large B-cell lymphoma cell line.
Data indicate that silencing of hypoxia-inducible factor-1 beta (HIF-1beta) sensitizes tumor cells to hypoxic apoptosis.
ARNT expression in the placental vasculature mediates key angiogenic expression and fetoplacental endothalial cell angiogenesis, and low ARNT expression in FGRadv ECs appears to be a key factor in deficient angiogenesis.
findings suggest that TACC3 (show TACC3 Antibodies) could be recruited as a bridge to cooperatively mediate between the HIF-2alpha (show EPAS1 Antibodies) PAS (show PASK Antibodies)-B.ARNT PAS (show PASK Antibodies)-B complex, thereby participating more directly in HIF-dependent gene transcription than previously anticipated
The objective of this review is therefore to highlight and summarize current knowledge regarding the hypoxia-dependent upregulation of ARNT
These promoters possess potential signature sequences for common as well as different transcription factors suggesting complex regulation of Arnt gene.
The only in vivo defects found in beta-Arnt mice were significant increases in the respiratory exchange ratio and in vivo carbohydrate oxidation, and a decrease in lipid oxidation
hepatocyte ARNT is not a requirement for initiation of liver fibrogenesis, but does regulate pro-fibrotic gene expression and macrophage accumulation.
HIF-1beta hepatocyte-specific knockout mice had less liver injury and steatosis in response to Gao-binge ethanol treatment.
Candidate gene analysis focused on Arnt as an influence on circadian regulation in the 'drinking in the dark' phenotype of alcohol consumption.
crystal structures for each of mouse HIF-2alpha (show EPAS1 Antibodies)-ARNT and HIF-1alpha (show HIF1A Antibodies)-ARNT heterodimers in states that include bound small molecules and their hypoxia response element
We determined that ARNT is essential for adult and fetal hematopoietic stem cell viability and homeostasis.
ARNT is a critical regulator of myocardial fatty acid metabolism and its deletion leads to cardiomyopathy and an increase in triglyceride accumulation through PPARA (show PPARA Antibodies).
This study demonstrates for the first time the requirement of HIF1 (show SETD2 Antibodies) for FSH (show BRD2 Antibodies)-regulated Vegfa (show VEGFA Antibodies) expression in vivo and that HIF1 (show SETD2 Antibodies) acts via a single hypoxia response element in the Vegfa (show VEGFA Antibodies) promoter to exert its regulatory functions.
Outcomes for islet transplants lacking beta-cell ARNT were poor.
The aryl hydrocarbon (Ah) receptor is involved in the induction of several enzymes that participate in xenobiotic metabolism. The ligand-free, cytosolic form of the Ah receptor is complexed to heat shock protein 90. Binding of ligand, which includes dioxin and polycyclic aromatic hydrocarbons, results in translocation of the ligand-binding subunit only to the nucleus. Induction of enzymes involved in xenobiotic metabolism occurs through binding of the ligand-bound Ah receptor to xenobiotic responsive elements in the promoters of genes for these enzymes. This gene encodes a protein that forms a complex with the ligand-bound Ah receptor, and is required for receptor function. The encoded protein has also been identified as the beta subunit of a heterodimeric transcription factor, hypoxia-inducible factor 1. A t(1\;12)(q21\;p13) translocation, which results in a TEL-ARNT fusion protein, is associated with acute myeloblastic leukemia. Alternative splicing results in multiple transcript variants.
aryl hydrocarbon receptor nuclear translocator
, aryl hydrocarbon receptor nuclear translocater
, ARNT protein
, HIF-1 beta
, dioxin receptor, nuclear translocator
, hypoxia-inducible factor 1 beta
, hypoxia-inducible factor 1-beta
, class E basic helix-loop-helix protein 2
, hypoxia-inducible factor 1, beta subunit
, Aryl hydrocarbon receptor nuclear translocator 1