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anti-Ataxin 2-Binding Protein 1 (A2BP1) Antibodies

The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Additionally we are shipping Ataxin 2-Binding Protein 1 Proteins (8) and Ataxin 2-Binding Protein 1 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
A2BP1 54715 Q9NWB1
A2BP1 268859 Q9JJ43
A2BP1 302920  
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Top anti-Ataxin 2-Binding Protein 1 Antibodies at antibodies-online.com

Showing 10 out of 95 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-A2BP1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Human brain 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB Host: Rabbit  Target Name: Rbfox1  Sample Tissue: Mouse Testis lysates  Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-A2BP1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: HepG2 cell lysate WB Suggested Anti-A2BP1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ICC, IF, IHC (p), WB Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Mouse Un-conjugated ICC, IF, IHC, WB Western blot of mouse brain homogenates stained with MCA-Fox1. Antibody binds closely spaced 48 kDa and 46 kDa bands. Rat brain neural cultures stained with ABIN1580418 (green), rabbit polyclonal antibody to NF-M RPCA-NF-M (red) and DNA (blue). The ABIN1580418 antibody reveals nuclear and distal cytoplasmic staining for Fox1, and the complete absence of staining of non-neuronal cells. 100 μL Log in to see 2 to 3 Days
$220.00
Details
REACT_Chlamydomonas reinhardtii Rabbit Un-conjugated IF, WB   200 μL Log in to see 5 to 6 Days
$467.78
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Mouse Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC (p), WB Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$676.50
Details

A2BP1 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-Ataxin 2-Binding Protein 1 Antibodies

  1. Human Monoclonal A2BP1 Primary Antibody for ICC, IF - ABIN1580418 : Shibata, Huynh, Pulst: A novel protein with RNA-binding motifs interacts with ataxin-2. in Human molecular genetics 2000 (PubMed)
    Show all 4 references for ABIN1580418

  2. Chlamydomonas reinhardtii (C. reinhardtii) Polyclonal A2BP1 Primary Antibody for IF, WB - ABIN108467 : Terauchi, Peers, Kobayashi, Niyogi, Merchant: Trophic status of Chlamydomonas reinhardtii influences the impact of iron deficiency on photosynthesis. in Photosynthesis research 2010 (PubMed)
    Show all 3 references for ABIN108467

  3. Cow (Bovine) Polyclonal A2BP1 Primary Antibody for WB - ABIN2787590 : Uhl, Liu, Drgon, Johnson, Walther, Rose, David, Niaura, Lerman: Molecular genetics of successful smoking cessation: convergent genome-wide association study results. in Archives of general psychiatry 2008 (PubMed)

  4. Human Polyclonal A2BP1 Primary Antibody for WB - ABIN2779139 : Fogel, Wexler, Wahnich, Friedrich, Vijayendran, Gao, Parikshak, Konopka, Geschwind: RBFOX1 regulates both splicing and transcriptional networks in human neuronal development. in Human molecular genetics 2012 (PubMed)

More Antibodies against Ataxin 2-Binding Protein 1 Interaction Partners

Zebrafish Ataxin 2-Binding Protein 1 (A2BP1) interaction partners

  1. This study underlines that tightly regulated splicing is necessary for unconstrained cardiac function and renders the splicing regulator (show PTBP2 Antibodies) rbfox1 an interesting target for investigation in human heart failure and cardiomyopathy.

Chlamydomonas reinhardtii (C. reinhardtii) Ataxin 2-Binding Protein 1 (A2BP1) interaction partners

  1. When the abundance of the FOX1 gene product is reduced, Chlamydomonas cells grow poorly in iron-deficient medium, but not in iron-replete medium, suggesting that FOX1-dependent iron uptake is a high-affinity pathway.

Human Ataxin 2-Binding Protein 1 (A2BP1) interaction partners

  1. study identifies regulation of RNA splicing by RBFox1 as an important player in transcriptome reprogramming during heart failure that influence pathogenesis of the disease

  2. The SNP rs1478697 in A2BP1 may be associated with antipsychotic induced weight gain induced by 8-week treatment with olanzapine.

  3. This study underlines that tightly regulated splicing is necessary for unconstrained cardiac function and renders the splicing regulator (show PTBP2 Antibodies) rbfox1 an interesting target for investigation in human heart failure and cardiomyopathy.

  4. Cytoplasmic Rbfox1 target mRNAs were enriched in genes involved in cortical development and autism

  5. The Genome-wide association study showed a significant association for a variant within the RBFOX1 gene with generalized anxiety disorder.

  6. This study suggested that exonic RBFOX1 deletions are involved in the broad spectrum of focal and generalized epilepsies.

  7. RBFOX proteins can facilitate the splicing of micro-exons. We also found that PTBP1 (show PTBP1 Antibodies) likely regulates the inclusion of micro-exons, possibly by repressing the inclusion of micro-exons that are enhanced by RBFOX proteins and other splicing factors.[RBFOX]

  8. Copy Number Variations in CTNNA3 (show CTNNA3 Antibodies) and RBFOX1 Associate with Pediatric Food Allergy

  9. Reduced RBFOX1 activity in myotonic dystrophy type 1 tissues may amplify several of the splicing alterations caused by the deficiency in MBNL1 (show MBNL1 Antibodies).

  10. RBFOX1 promotes the skipping of APP (show APP Antibodies) exon 7, but not the inclusion of exon 8.

Mouse (Murine) Ataxin 2-Binding Protein 1 (A2BP1) interaction partners

  1. Cytoplasmic Rbfox1 target mRNAs were enriched in genes involved in cortical development and autism

  2. Gain- and loss-of-function experiments demonstrated that Rbfox1 and Rbfox2 (show RBM9 Antibodies) cooperate in promoting Mef2D (show MEF2D Antibodies) splicing and subsequent myogenesis.

  3. Rbfox1 regulates RNA splicing required for skeletal muscle structure and function.

  4. Fox-1, expressed specifically in the neural cell stage, promoted Mef2c (show MEF2C Antibodies) exon beta inclusion via the GCAUG.

  5. The results suggest that in neuronal tissues A2BP1 plays important roles, which are regulated in a spatiotemporal manner.

  6. our results suggest that a component of FSHD pathogenesis may arise by over-expression of FRG1 (show FRG1 Antibodies), reducing Rbfox1 levels and leading to aberrant expression of an altered Calpain 3 (show CAPN3 Antibodies) protein through dysregulated splicing

  7. Fox-1 splices mRNAs encoding proteins important in synaptic transmission and membrane excitation.

  8. The splicing regulator (show PTBP2 Antibodies) Rbfox1 controls neuronal excitation in the mammalian brain.

  9. These data indicate that A2BP1 mutations may clinically affect very selective forebrain neuron types from early periods of development.

  10. The present study provides evidence that alternative neuronal nPTB (show PTBP2 Antibodies) and Fox-1/Fox-2 (show RBM9 Antibodies) isoforms are also produced in lenses

Ataxin 2-Binding Protein 1 (A2BP1) Antigen Profile

Protein Summary

The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with A2BP1

  • RNA binding protein, fox-1 homolog (C. elegans) 1 (RBFOX1) antibody
  • ataxin 2-binding protein 1 (LOC453899) antibody
  • ataxin 2-binding protein 1 (LOC100357475) antibody
  • RNA binding protein, fox-1 homolog (C. elegans) 1 (rbfox1) antibody
  • multicopper ferroxidase (FOX1) antibody
  • RNA binding protein, fox-1 homolog (C. elegans) 1 (Rbfox1) antibody
  • 2BP1 antibody
  • A2bp antibody
  • A2bp1 antibody
  • fox-1 antibody
  • FOX1 antibody
  • Hrnbp1 antibody
  • zgc:103635 antibody

Protein level used designations for A2BP1

RNA binding protein, fox-1 homolog (C. elegans) 1 , ataxin 2-binding protein 1 , RNA binding protein fox-1 homolog 1 , ataxin-2-binding protein 1 , fox-1 homolog A , hexaribonucleotide-binding protein 1 , ataxin 2 binding protein 1 , hexaribonucleotide binding protein 1 , RNA binding protein, fox-1 homolog 1

GENE ID SPECIES
416645 Gallus gallus
453899 Pan troglodytes
100357475 Oryctolagus cuniculus
449554 Danio rerio
5720109 Chlamydomonas reinhardtii
54715 Homo sapiens
521304 Bos taurus
268859 Mus musculus
302920 Rattus norvegicus
100172936 Pongo abelii
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