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B-Cell Linker (BLNK) ELISA Kits

BLNK encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. Additionally we are shipping B-Cell Linker Antibodies (189) and B-Cell Linker Proteins (14) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
BLNK 17060 Q9QUN3
BLNK 29760 Q8WV28
BLNK 499356 Q4KM52
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Top B-Cell Linker ELISA Kits at antibodies-online.com

Showing 10 out of 44 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human
96 Tests Log in to see 8 to 9 Days
$680.63
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Pig
96 Tests Log in to see 8 to 9 Days
$770.00
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Monkey
96 Tests Log in to see 8 to 9 Days
$770.00
Details
Guinea Pig
96 Tests Log in to see 8 to 9 Days
$770.00
Details
Chicken
96 Tests Log in to see 8 to 9 Days
$770.00
Details
Rabbit
96 Tests Log in to see 8 to 9 Days
$770.00
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Please inquire
2 x 96 Tests Log in to see 2 to 3 Days
$258.50
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Mammalian
0.01 1000 Tests Log in to see 2 to 3 Days
$231.00
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Human
96 Tests Log in to see 2 to 3 Days
$480.00
Details
Human
96 Tests Log in to see 2 to 3 Days
$480.00
Details

Top referenced B-Cell Linker ELISA Kits

  1. ABIN2815083 : LOWRY, ROSEBROUGH, FARR, RANDALL: Protein measurement with the Folin phenol reagent. in The Journal of biological chemistry 1952 (PubMed)

  2. ABIN593356 : Chen, Sood, McIntire, Roth, Rabkin: Leucine-stimulated mTOR signaling is partly attenuated in skeletal muscle of chronically uremic rats. in American journal of physiology. Endocrinology and metabolism 2011 (PubMed)

More ELISA Kits for B-Cell Linker Interaction Partners

Mouse (Murine) B-Cell Linker (BLNK) interaction partners

  1. Authors demonstrate leukemogenicity of PAX5 (show PAX5 ELISA Kits)-PML (show PML ELISA Kits) by introducing it into normal mouse pro-B cells; B-cell linker protein (Blnk) is repressed by PAX5 (show PAX5 ELISA Kits)-PML (show PML ELISA Kits) in leukemia cells; enforced expression of Blnk increases survival despite introduction of PAX5 (show PAX5 ELISA Kits)-PML (show PML ELISA Kits).

  2. B-cell linker protein expression contributes to controlling allergic and autoimmune diseases by mediating IL-10 (show IL10 ELISA Kits) production in regulatory B cells.

  3. Tumor suppressor BLNK is a target of transcriptional activation by PU.1 and Spi-B (show SPIB ELISA Kits) in the B cell lineage.

  4. a novel negative feedback regulation of BCR (show BCR ELISA Kits) signaling by HPK1-mediated phosphorylation, ubiquitination, and subsequent degradation of the activated BLNK

  5. CMTM7 (show CMTM7 ELISA Kits) functions to link sIgM and BLNK in the plasma membrane.

  6. Live cell imaging and co-immunoprecipitation experiments confirmed that both SLP65 and CIN85 (show SH3KBP1 ELISA Kits) are both required for the onset and progression phases of B-cell antigen receptor signal transduction.

  7. malignant transformation of Btk (show BTK ELISA Kits)/Slp65 double-deficient pre-B cells is independent of deregulated V(D)J recombination activity.

  8. Swip-1 (show WSB1 ELISA Kits) provides a membrane scaffold that is required for the Syk (show SYK ELISA Kits)-, SLP-65-, and PLCgamma2 (show PLCG2 ELISA Kits)-dependent BCR (show BCR ELISA Kits)-induced calcium flux.

  9. malignant transformation of Slp65(-/-) pre-B cells involves disruption of the p19(Arf)-Mdm2-p53 tumor suppressor pathway

  10. The direct recruitment of BLNK to immunoglobulin alpha couples the B-cell antigen receptor to distal signaling pathways

Human B-Cell Linker (BLNK) interaction partners

  1. vesicular signaling scaffolds are required for B cell activation indicates that vesicles may deliver preassembled signaling cargo to sites of BCR (show BCR ELISA Kits) activation.

  2. early Ca(2 (show CA2 ELISA Kits)+) fluxing provides feed-forward signal amplification by promoting anchoring of the PLCgamma2 (show PLCG2 ELISA Kits) C2 domain to phospho-SLP65.

  3. up-regulation of BLNK is associated with RUNX1 (show RUNX1 ELISA Kits) mutations in cytogenetically normal acute myeloid leukemia (show BCL11A ELISA Kits).

  4. Live cell imaging and co-immunoprecipitation experiments confirmed that both SLP65 and CIN85 (show SH3KBP1 ELISA Kits) are both required for the onset and progression phases of B-cell antigen receptor signal transduction.

  5. 16 of the 34 childhood pre-B acute lymphoblastic leukaemia samples that were tested showed a complete loss or drastic reduction of SLP-65 expression

  6. The BLNK protein is present in the majority of mediastinal B cell lymphomas.

  7. In B cells SLP-65 exists in a 180 kDa complex as well as in monomeric form.

  8. V(H) gene rearrangement represents a frequent feature in B-lymphoid malignancy, which can be attributed to SLP65 deficiency in many cases.

  9. Syk (show SYK ELISA Kits) is required to link phosphorylated SLP-65 to Ca(2 (show CA2 ELISA Kits)+) mobilization.

  10. Plasmacytoid dendritic cells express a signalosome consisting of Lyn (show LYN ELISA Kits), Syk (show SYK ELISA Kits), Btk (show BTK ELISA Kits), Slp65 (Blnk) and PLCgamma2 (show PLCG2 ELISA Kits). Triggering CD303 leads to tyrosine phosphorylation of Syk (show SYK ELISA Kits), Slp65, PLCgamma2 (show PLCG2 ELISA Kits) & cytoskeletal proteins.

B-Cell Linker (BLNK) Antigen Profile

Antigen Summary

This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with B-Cell Linker (BLNK) ELISA Kits

  • B-cell linker (BLNK) antibody
  • B-cell linker (blnk) antibody
  • B-cell linker protein (blnk) antibody
  • B cell linker (Blnk) antibody
  • B-cell linker (Blnk) antibody
  • B-cell linker-like (LOC100354716) antibody
  • AGM4 antibody
  • BASH antibody
  • bca antibody
  • blnk antibody
  • BLNK-S antibody
  • Ly-57 antibody
  • LY57 antibody
  • Lyw-57 antibody
  • MGC147045 antibody
  • SLP-65 antibody
  • SLP65 antibody

Protein level used designations for B-Cell Linker (BLNK) ELISA Kits

B-cell linker , B-cell linker protein , b-cell linker protein-like , B-cell adapter containing a SH2 domain protein , B-cell adapter containing a Src homology 2 domain protein , cytoplasmic adapter protein , lymphocyte antigen 57 , src homology 2 domain-containing leukocyte protein of 65 kDa , B cell adaptor containing SH2 domain , B cell linker protein , B-cell activation , Src homology 2 domain-containing leukocyte protein of 65 kDa , Src homology [SH2] domain-containing leukocyte protein of 65 kD , B cell linker protein BLNK , B-cell adapter SH2 domain-containing protein , SLP-65

GENE ID SPECIES
100070841 Equus caballus
405764 Danio rerio
450641 Pan troglodytes
548350 Xenopus (Silurana) tropicalis
704363 Macaca mulatta
100306798 Salmo salar
100456635 Pongo abelii
100481331 Ailuropoda melanoleuca
100593492 Nomascus leucogenys
17060 Mus musculus
29760 Homo sapiens
395733 Gallus gallus
499356 Rattus norvegicus
486814 Canis lupus familiaris
100152350 Sus scrofa
510393 Bos taurus
100712978 Cavia porcellus
101111241 Ovis aries
100354716 Oryctolagus cuniculus
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