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The protein encoded by BAG5 is a member of the BAG1-related protein family. Additionally we are shipping BAG5 Proteins (8) and many more products for this protein.
Showing 10 out of 153 products:
Human Monoclonal BAG5 Primary Antibody for WB - ABIN393381
Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010
Show all 5 references for ABIN393381
Human Polyclonal BAG5 Primary Antibody for EIA, WB - ABIN950599
Höhfeld, Jentsch: GrpE-like regulation of the hsc70 chaperone by the anti-apoptotic protein BAG-1. in The EMBO journal 1997
Show all 3 references for ABIN950599
Cow (Bovine) Polyclonal BAG5 Primary Antibody for IHC, IHC (p) - ABIN4282961
Gamerdinger, Kaya, Wolfrum, Clement, Behl: BAG3 mediates chaperone-based aggresome-targeting and selective autophagy of misfolded proteins. in EMBO reports 2011
Rat (Rattus) Polyclonal BAG5 Primary Antibody for IHC (p), WB - ABIN265064
Takayama, Xie, Reed: An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators. in The Journal of biological chemistry 1999
Human Polyclonal BAG5 Primary Antibody for ELISA, WB - ABIN4282962
Kalia, Lee, Smith, Liu, Crocker, Thorarinsdottir, Glover, Fon, Park, Lozano: BAG5 inhibits parkin and enhances dopaminergic neuron degeneration. in Neuron 2004
Subsequent BAG5 upregulation ameliorated the tumor-suppressive effects of miR (show MLXIP Antibodies)-127-3p overexpression in epithelial ovarian cancer (EOC). In conclusion, miR (show MLXIP Antibodies)-127-3p functions as a tumor suppressor in EOC, and its influence on EOC is directly through regulation of BAG5.
High BAG5 expression is associated with pancreatic cancer.
This study showed that BAG2 (show BAG2 Antibodies) (Bcl-2 (show BCL2 Antibodies) associated athanogene family protein 2) and BAG5 (Bcl-2 (show BCL2 Antibodies)-associated athanogene family protein 5 (show CAPS Antibodies)) stabilise pathogenic ataxin3-80Q by inhibiting its ubiquitination.
BAG5 protects against mitochondrial oxidative damage through regulating PINK1 (show PINK1 Antibodies) degradation.
BAG5 is a binding partners of LRRK2 (show LRRK2 Antibodies) and part of a complex that promotes clearance of Golgi-derived vesicles through the autophagy-lysosome system.
Bag5 is overexpressed in prostate cancer and plays a role in endoplamic reticulum-stress induced apoptosis. Furthermore we have identified GRP78/BiP (show HSPA5 Antibodies) as a novel interaction partner of Bag5.
BAG5 directly interacts with Parkin and stabilizes Parkin via the ubiquitin-mediated proteasomal pathway.
A novel function for BAG5 as a modulator of CHIP E3 ubiquitin ligase (show MUL1 Antibodies) activity with implications for CHIP-mediated regulation of alpha-syn oligomerization.
We replicated the association of BCL2L11 (show BCL2L11 Antibodies) and CASP9 (show CASP9 Antibodies) with non-Hodgkin's lymphoma risk at the gene and SNP level, and identified novel associations with BCLAF1 (show BCLAF1 Antibodies) and BAG5.
Bcl-2-associated athanogene 5 (BAG5) is a negative regulator of both Hsp70 and parkin function that sensitizes dopaminergic neurons to injury-induced death.
knockdown of Bag5 exacerbated Abeta1-42-induced apoptosis.
The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene.
BCL2-associated athanogene 5
, BAG family molecular chaperone regulator 5
, BAG family molecular chaperone regulator 5-like
, BAG-family molecular chaperone regulator-5
, bcl-2-associated athanogene 5
, BAG-family molecular chaperone regulator-5 (BAG-5)