BAG5 antibody (C-Term)

Catalog No. ABIN2788981

Cited in 1 publication. The Rabbit Polyclonal anti-BAG5 antibody (ABIN2788981) specifically detects BAG5 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig and Pig samples.

Quick Overview for BAG5 antibody (C-Term) (ABIN2788981)

Target: BAG5 (BCL2-Associated Athanogene 5 (BAG5))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BAG5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BAG5 Antibody

Binding Specificity: C-Term

Purpose: BAG5 Antibody - C-terminal region

Sequence: LEKRKLFACE EHPSHKAVWN VLGNLSEIQG EVLSFDGNRT DKNYIRLEEL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against BAG5. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61996-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-BAG5 antibody (ABIN2788981)

Yue, Zhao, Huang, Li, Zhu, Feng, Hu: "A novel mutant p53 binding partner BAG5 stabilizes mutant p53 and promotes mutant p53 GOFs in tumorigenesis." in: Cell discovery, Vol. 2, pp. 16039, (2016) (PubMed).

Target Details for BAG5

Target: BAG5 (BCL2-Associated Athanogene 5 (BAG5))

Alternative Name: BAG5

Background:

Background Information: The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene.

Gene Name: BCL2-associated athanogene 5

Alternative Symbols: BAG-5

Protein Name: BAG family molecular chaperone regulator 5

Molecular Weight: 56kDa

Gene ID: 9529

NCBI Accession: NP_001015049

UniProt: Q9UL15

Pathways: SARS-CoV-2 Protein Interactome