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The protein encoded by BIRC7 is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. Additionally we are shipping Baculoviral IAP Repeat-Containing 7 Proteins (18) and Baculoviral IAP Repeat-Containing 7 Kits (10) and many more products for this protein.
Showing 10 out of 169 products:
Human Monoclonal BIRC7 Primary Antibody for ICC, IF - ABIN252506
Nachmias, Ashhab, Bucholtz, Drize, Kadouri, Lotem, Peretz, Mandelboim, Ben-Yehuda: Caspase-mediated cleavage converts Livin from an antiapoptotic to a proapoptotic factor: implications for drug-resistant melanoma. in Cancer research 2003
Show all 21 references for ABIN252506
Human Polyclonal BIRC7 Primary Antibody for EIA, IHC (p) - ABIN358607
Gazzaniga, Gradilone, Giuliani, Gandini, Silvestri, Nofroni, Saccani, Frati, Aglianò: Expression and prognostic significance of LIVIN, SURVIVIN and other apoptosis-related genes in the progression of superficial bladder cancer. in Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2002
Show all 5 references for ABIN358607
Human Polyclonal BIRC7 Primary Antibody for IHC (p), IP - ABIN252145
Liu, Kong, Zeng, Liu, Bi, Jiang, Han: Livin may serve as a marker for prognosis of bladder cancer relapse and a target of bladder cancer treatment. in Urologic oncology 2009
Show all 4 references for ABIN252145
Human Monoclonal BIRC7 Primary Antibody for WB - ABIN2668574
Jiang, Zhou, Yuen, Corless, Heinrich, Fletcher, Demetri, Widlund, Fisher, Hodi: Imatinib targeting of KIT-mutant oncoprotein in melanoma. in Clinical cancer research : an official journal of the American Association for Cancer Research 2008
Show all 3 references for ABIN2668574
Human Polyclonal BIRC7 Primary Antibody for EIA, IHC (p) - ABIN500182
Kasof, Gomes: Livin, a novel inhibitor of apoptosis protein family member. in The Journal of biological chemistry 2001
Show all 3 references for ABIN500182
Human Polyclonal BIRC7 Primary Antibody for IF (p), IHC (p) - ABIN672561
Zhang, Peng, Luo, Zhou: Prospective experimental studies on the renal protective effect of ulinastatin after paraquat poisoning. in World journal of emergency medicine 2014
Human Polyclonal BIRC7 Primary Antibody for WB - ABIN782874
Puri, Eller, Byers, Dykstra, Kubera, Gilchrest: Telomere-based DNA damage responses: a new approach to melanoma. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004
Human Polyclonal BIRC7 Primary Antibody for WB - ABIN2792130
Dynek, Chan, Liu, Zha, Fairbrother, Vucic: Microphthalmia-associated transcription factor is a critical transcriptional regulator of melanoma inhibitor of apoptosis in melanomas. in Cancer research 2008
Human Polyclonal BIRC7 Primary Antibody for IHC (p), WB - ABIN390073
Vucic, Deshayes, Ackerly, Pisabarro, Kadkhodayan, Fairbrother, Dixit: SMAC negatively regulates the anti-apoptotic activity of melanoma inhibitor of apoptosis (ML-IAP). in The Journal of biological chemistry 2002
Data showed that Livin knock-down suppressed cell proliferation and inhibited cell invasion, accompanied by downregulation of VEGF (show VEGFA Antibodies) and MMP-2 (show MMP2 Antibodies)/-9. Its silencing resulted in the prevention of xenograft tumor formation.
Birc7 is a late fiber gene of the mouse lens. Its expression in cells bordering the OFZ is consistent with a role in organelle degradation, a process in which the ubiquitin proteasome pathway has been implicated previously.
ML-IAP is dispensable for both normal mouse development and ocular homoeostasis.
The apoptosisinducing effects of livin and surivin knockdown were investigated using a Hoechst staining kit.
Expression of livin, survivin (show BIRC5 Antibodies) and caspase-3 (show CASP3 Antibodies) are closely related to the occurrence and development of prostatic cancer.
Our results suggested the important role of Livin and its partner molecule in the process of VSV treatment
These findings suggest that livin may be used as a novel target for tumor gene therapy.
Upregulation of Livin expression and downregulation of caspase (show CASP3 Antibodies) activity are observed under cycling and chronic hypoxia in glioblastoma cells and xenografts.
Livin expression was higher in condyloma acuminatum than in normal cells and was correlated with survivin (show BIRC5 Antibodies) and Ki-67 (show MKI67 Antibodies).
Livin gene has a high expression in osteosarcoma and inhibits apoptosis in tumor tissue.
livin is associated with invasive and oncogenic phenotypes such as tumor cell invasion, tumor cell migration, tumor cell proliferation, and resistance to apoptosis in human oral squamous cell carcinoma cells.
These data suggest that livin overexpression plays an important role in tumor invasiveness by mediating resistance to apoptosis.
The protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide.
baculoviral IAP repeat-containing 5-like
, baculoviral IAP repeat-containing 7
, baculoviral IAP repeat-containing 7 (livin)
, E3 ubiquitin-protein ligase EIAP
, Embryonic/Egg IAP
, baculoviral IAP repeat-containing protein 7
, RING finger protein 50
, kidney inhibitor of apoptosis protein
, livin inhibitor of apoptosis
, melanoma inhibitor of apoptosis protein