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anti-Bicaudal C Homolog 1 (Drosophila) (BICC1) Antibodies

BICC1 encodes an RNA-binding protein that is active in regulating gene expression by modulating protein translation during embryonic development. Additionally we are shipping Bicaudal C Homolog 1 (Drosophila) Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
BICC1 80114 Q9H694
BICC1 83675 Q99MQ1
BICC1 361832  
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Top anti-Bicaudal C Homolog 1 (Drosophila) Antibodies at antibodies-online.com

Showing 10 out of 50 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of BICC1 Antibody (N-term) (ABIN390954) in HL-60... Formalin-fixed and paraffin-embedded human brain tissue reacted with B... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$283.50
Details
Dog Goat Un-conjugated EIA, IP HEK293 overexpressing Human BICC1 with N-terminal FLAG, probed with Ra... 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Goat Un-conjugated ELISA   0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit PE ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$221.76
Details

BICC1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
,
Mouse (Murine) ,

Rat (Rattus) ,

Top referenced anti-Bicaudal C Homolog 1 (Drosophila) Antibodies

  1. Human Polyclonal BICC1 Primary Antibody for WB - ABIN1944768 : Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: Complete sequencing and characterization of 21,243 full-length human cDNAs. ... in Nature genetics 2003 (PubMed)
    Show all 3 references for ABIN1944768

  2. Human Polyclonal BICC1 Primary Antibody for IHC (p), WB - ABIN390954 : Grupe, Li, Rowland, Nowotny, Hinrichs, Smemo, Kauwe, Maxwell, Cherny, Doil, Tacey, van Luchene, Myers, Wavrant-De Vrièze, Kaleem, Hollingworth, Jehu, Foy, Archer, Hamilton, Holmans, Morris, Catanese et al.: A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. ... in American journal of human genetics 2005 (PubMed)
    Show all 2 references for ABIN390954

More Antibodies against Bicaudal C Homolog 1 (Drosophila) Interaction Partners

Zebrafish Bicaudal C Homolog 1 (Drosophila) (BICC1) interaction partners

  1. These results demonstrate that the function of Bicc1 in the kidney is evolutionarily conserved, thus supporting the use of zebrafish as an alternative in vivo model to study the role of mammalian Bicc1 in renal cyst formation.

Human Bicaudal C Homolog 1 (Drosophila) (BICC1) interaction partners

  1. findings identify a role for increased levels of BICC1 in the pathophysiology of depressive behavior

  2. Polymorphisms in intron 2 of BICC1 are associated with its expression and bone (show BEST1 Antibodies) mineral density (BMD)

  3. The minor T-allele of BICC1 has a protective role against major depressive disorder and its known structural and functional brain changes.

  4. The nonsense mutation identified in BICC1 and associated with cystic renal dysplasia results in a complete loss of Wnt (show WNT2 Antibodies) inhibitory activity. The point mutation in the SAM (show TTN Antibodies) domain results in a 22% loss of activity.

Mouse (Murine) Bicaudal C Homolog 1 (Drosophila) (BICC1) interaction partners

  1. Polymerization is a novel disease-relevant mechanism both to stabilize Bicc1 and to present associated mRNAs in specific silencing platforms.

  2. discovered that loss of the Pkd1 (show PKD1 Antibodies) gene product, polycystin-1 (PC1 (show PKD1 Antibodies)), whose mutation causes human autosomal dominant polycystic kidney disease (ADPKD), downregulates Bicc1 expression in vitro and in vivo

  3. Bicc1 is a novel regulator of osteoblastogenesis and bone mineral density (BMD (show BEST1 Antibodies))

  4. Bicc1 KH domains bind the 3' UTRs of AC6 (show ADCY6 Antibodies) and PKIa (show PKIA Antibodies) mRNAs and cognate miRNA precursors, whereas the SAM (show TTN Antibodies) domain loads a silencing complex with AGO2 (show EIF2C2 Antibodies). AC6 (show ADCY6 Antibodies) and PKIa (show PKIA Antibodies) protein levels increase in cystic Bicc1-/- mouse kidneys.

  5. lack of Bicc1 leads to disruption of normal cell-cell junctions.

  6. Data suggest that Bicc1 functions by modulating the expression of polycystin 2 (Pkd2 (show PKD2 Antibodies) by antagonizing the repressive activity of the miR-17 microRNA family on the 3'UTR (show UTS2R Antibodies) of Pkd2 (show PKD2 Antibodies) mRNA.

  7. Binds homoribopolymers in vitro; the third K homology domain is necessary and sufficient for in vitro Bicc1 RNA binding.

  8. Bicc1 and SamCystin (show ANKS6 Antibodies) interact at the protein level suggesting that they function in a common molecular pathway that when perturbed, is involved in cystogenesis.

  9. Data report that targeted inactivation of BicC randomizes left-right asymmetry by disrupting the planar alignment of motile cilia required for cilia-driven fluid flow, and that BicC can uncouple Dvl2 (show DVL2 Antibodies) signaling from the canonical Wnt (show WNT2 Antibodies) pathway.

Bicaudal C Homolog 1 (Drosophila) (BICC1) Antigen Profile

Protein Summary

This gene encodes an RNA-binding protein that is active in regulating gene expression by modulating protein translation during embryonic development. Mouse studies identified the corresponding protein to be under strict control during cell differentiation and to be a maternally provided gene product.

Gene names and symbols associated with BICC1

  • bicaudal C homolog 1 (Drosophila) (BICC1) antibody
  • bicaudal C homolog 1b (Drosophila) (bicc1b) antibody
  • bicaudal C homolog 1 (bicc1) antibody
  • bicaudal C homolog 1 (Drosophila) (Bicc1) antibody
  • Bic-C antibody
  • Bicaudal-C antibody
  • BICC antibody
  • bicc1 antibody
  • bpk antibody
  • CYSRD antibody
  • jcpk antibody
  • x-Bic-C antibody
  • xBic-C antibody

Protein level used designations for BICC1

bicaudal C homolog 1 (Drosophila) , bicaudal C homolog 1-like , bicaudal C homolog 1 , protein bicaudal C homolog 1-like , bic-C , protein bicaudal C homolog 1 , juvenile congenital polycystic kidney disease , polycystic kidney mutation of BALB/c origin

GENE ID SPECIES
423604 Gallus gallus
450473 Pan troglodytes
537799 Bos taurus
571411 Danio rerio
733856 Xenopus (Silurana) tropicalis
701228 Macaca mulatta
100013824 Monodelphis domestica
100072191 Equus caballus
100412529 Callithrix jacchus
100466363 Ailuropoda melanoleuca
100589900 Nomascus leucogenys
80114 Homo sapiens
608626 Canis lupus familiaris
83675 Mus musculus
361832 Rattus norvegicus
100154253 Sus scrofa
Selected quality suppliers for anti-Bicaudal C Homolog 1 (Drosophila) (BICC1) Antibodies
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