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anti-CD207 Molecule, Langerin (CD207) Antibodies

The protein encoded by CD207 is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. Additionally we are shipping CD207 Molecule, Langerin Proteins (8) and CD207 Molecule, Langerin Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CD207 246278 Q8VBX4
CD207 50489 Q9UJ71
CD207 502852  
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Top anti-CD207 Molecule, Langerin Antibodies at antibodies-online.com

Showing 10 out of 100 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse PE Neut 100 μg Log in to see 10 to 12 Days
$298.95
Details
Human Mouse APC FACS 100 μg Log in to see 10 to 12 Days
$320.68
Details
Human Mouse PE FACS, IHC 100 Tests Log in to see 10 to 12 Days
$282.64
Details
Human Rabbit Un-conjugated WB Host: Rabbit  Target Name: CD207  Sample Tissue: Fetal Kidney  Antibod... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse APC WB 100 Tests Log in to see 10 to 12 Days
$331.55
Details
Human Mouse PerCP FACS   100 Tests Log in to see 8 to 10 Days
$925.83
Details
Human Mouse Un-conjugated ICFC 100 μg Log in to see 10 to 12 Days
$211.97
Details
Mouse Rabbit Un-conjugated FACS, IHC (fro), IHC (p), WB Western blot analysis of langerin in mouse lung tissue lysate using 2 ... 100 μg Log in to see 8 to 10 Days
$507.83
Details
Human Mouse Un-conjugated IHC (f), IHC (p) 10 × 20 × IHC of Langerin (Clone 12D6) on FFPE skin tissue. Citrate pH... 7 mL Log in to see 14 to 16 Days
$544.77
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human cervical carcinoma labeled ... Formalin-fixed and paraffin embedded rat vascular endothelial cells la... 100 μL Log in to see 3 to 7 Days
$269.50
Details

CD207 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
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Top referenced anti-CD207 Molecule, Langerin Antibodies

  1. Human Monoclonal CD207 Primary Antibody for Neut - ABIN2662535 : Clausen, Kel: Langerhans cells: critical regulators of skin immunity? in Immunology and cell biology 2010 (PubMed)
    Show all 4 references for ABIN2662535

  2. Human Monoclonal CD207 Primary Antibody for FACS - ABIN2657032 : Merad, Ginhoux, Collin: Origin, homeostasis and function of Langerhans cells and other langerin-expressing dendritic cells. in Nature reviews. Immunology 2008 (PubMed)
    Show all 4 references for ABIN2657032

  3. Human Monoclonal CD207 Primary Antibody for ICFC - ABIN2664388 : Valladeau, Ravel, Dezutter-Dambuyant, Moore, Kleijmeer, Liu, Duvert-Frances, Vincent, Schmitt, Davoust, Caux, Lebecque, Saeland: Langerin, a novel C-type lectin specific to Langerhans cells, is an endocytic receptor that induces the formation of Birbeck granules. in Immunity 2000 (PubMed)
    Show all 3 references for ABIN2664388

  4. Human Monoclonal CD207 Primary Antibody for WB - ABIN2657030 : Mizumoto, Takashima: CD1a and langerin: acting as more than Langerhans cell markers. in The Journal of clinical investigation 2004 (PubMed)
    Show all 3 references for ABIN2657030

  5. Human Monoclonal CD207 Primary Antibody for FACS, IHC - ABIN2662533 : de Witte, Nabatov, Pion, Fluitsma, de Jong, de Gruijl, Piguet, van Kooyk, Geijtenbeek: Langerin is a natural barrier to HIV-1 transmission by Langerhans cells. in Nature medicine 2007 (PubMed)
    Show all 3 references for ABIN2662533

More Antibodies against CD207 Molecule, Langerin Interaction Partners

Mouse (Murine) CD207 Molecule, Langerin (CD207) interaction partners

  1. Langerin is expressed by the XCR1(+) "DC1" populat (show CD1C Antibodies)ion of mice.

  2. Langerin+ dermal dendritic cells appear to be site- and strain-specific

  3. TLR7 (show TLR7 Antibodies)-activated langerin(neg) dendritic cells trigger psoriatic plaque formation via IL-23 (show IL23A Antibodies)-mediated activation of innate IL-17 (show IL17A Antibodies)/IL-22 (show IL22 Antibodies)-producing lymphocytes, independently of IFN-I.

  4. model of epicutaneous ovalbumin (show OVA Antibodies) sensitization inducing an inflammatory skin resembling atopic dermatitis (AD) to explore the role of CD207 in the pathogenesis of AD

  5. Langerin-positive dendritic cells appear to be the predominant, though not exclusive, population responsible for in vivo transport of anti-DEC-205 (show LY75 Antibodies) antibodies from the skin to the draining lymph nodes in steady state and inflammation.

  6. Data demonstrated that CD207(+) CD8alpha(+) thymic DCs do not share a common origin with T cells but originate from intrathymic precursors.

  7. The normal corneal epithelium is endowed with CD11c (show ITGAX Antibodies)(+) Langerin+ cells that are LCs, whereas the stroma is endowed with a separate population of (non-LC) Langerin+ DCs.

  8. Comparable T helper 1 (Th1 (show HAND1 Antibodies)) and CD8 (show CD8A Antibodies) T-cell immunity by targeting HIV gag p24 to CD8 (show CD8A Antibodies) dendritic cells within antibodies to Langerin, DEC205 (show LY75 Antibodies), and Clec9A (show CLEC9A Antibodies).

  9. Langerhan cells and (Langerin(+)) dermal dendritic cells thus seem to have a redundant function in regulating contact hypersensitivity

  10. molecular cloning and expression of Langerin transcripts in dendritic cells

Human CD207 Molecule, Langerin (CD207) interaction partners

  1. This study shows that mutations in the Langerin gene are present in the analysed populations at different genotypic and allelic frequencies and further studies should be conducted to verify the role of these mutations in HIV-1 susceptibility.

  2. This study is the first to demonstrate that langerin represents an authentic receptor that binds and internalizes influenza A virus to facilitate infection.

  3. Data suggest that Langerin (CD207)-mediated binding of Yersinia pestis to antigen-presenting cells (APCs (show APCS Antibodies)) may promote its dissemination and infection.

  4. Langerin binds heparin (HEP)-like oligosaccharides in two different binding sites depending on the ligand size.

  5. The authors not only show that langerin and caveolin-1 (show CAV1 Antibodies) co-localize at the cell membrane and in vesicles but that caveolin-1 (show CAV1 Antibodies) mediated HIV-1 uptake is an intrinsic restriction mechanism present in human Langerhans cells that prevents HIV-1 infection.

  6. The impact of two carbohydrate recognition domains mutations, W264R and F241L, on langerin structure, function, and Birbeck granules assembly.

  7. Langerin is not expressed by freshly isolated CD1c (show CD1C Antibodies)(+) blood DCs but is rapidly induced on CD1c (show CD1C Antibodies)(+) DCs by serum or TGF-beta (show TGFB1 Antibodies) via an ALK-3 (show BMPR1A Antibodies)-dependent pathway.

  8. Cell-sorting experiments demonstrated that IDO1 (show IDO1 Antibodies) expression is found in a subset of CD1a (show CD1A Antibodies)(+)CD14 (show NDUFA2 Antibodies)(-)langerin(+) cells, expressing CD103 (show ITGAE Antibodies)

  9. However, the superoxide dismutase (show SOD1 Antibodies) C (SodC (show SOD1 Antibodies)) protein of the Mycobacterium leprae cell wall was identified as a langerin-reactive ligand.

  10. Both phases of HIV transfer from eLCs to T cells were inhibited when eLCs were pretreated with a mAb to langerin CRD (show CRX Antibodies) or when HIV was pretreated with a soluble langerin trimeric extracellular domain or by a CRD (show CRX Antibodies) homolog.

CD207 Molecule, Langerin (CD207) Antigen Profile

Protein Summary

The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity.

Gene names and symbols associated with CD207

  • CD207 molecule, langerin (CD207) antibody
  • CD207 antigen (Cd207) antibody
  • CD207 molecule, langerin (Cd207) antibody
  • CD207 antibody
  • CLEC4K antibody
  • RGD1565913 antibody

Protein level used designations for CD207

CD207 molecule, langerin , CD207 antigen, langerin , C-type lectin domain family 4 member K , Langerhans cell specific c-type lectin , langerin , C-type lectin domain family 4, member K , CD 207 antigen

GENE ID SPECIES
511000 Bos taurus
703420 Macaca mulatta
737419 Pan troglodytes
100580491 Nomascus leucogenys
246278 Mus musculus
50489 Homo sapiens
100037935 Sus scrofa
502852 Rattus norvegicus
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