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Involved in the costimulatory signal essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Additionally we are shipping PD-L1 Antibodies (320) and PD-L1 Proteins (71) and many more products for this protein.
Showing 10 out of 34 products:
Human PD-L1 ELISA Kit for Sandwich ELISA - ABIN577883
Atesoglu, Tarkun, Demirsoy, Geduk, Mehtap, Batman, Kaya, Cekmen, Gulbas, Hacıhanefioglu: Soluble Programmed Death 1 (PD-1) Is Decreased in Patients With Immune Thrombocytopenia (ITP): Potential Involvement of PD-1 Pathway in ITP Immunopathogenesis. in Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 2014
PD-1 (show PDCD1 ELISA Kits)/PD-L1 plays a crucial role in maintaining immune tolerance induced by UVB-iDCs, as well as in actively controlling effector T cells specific to alloantigens.
Data show that Qiyusanlong decoction (QYSL) can moderately inhibit the growth of the transplanted tumor by decreasing programmed death 1 (show PDCD1 ELISA Kits) and programmed death ligand 1 (PD-1 (show PDCD1 ELISA Kits)/PD-L1) level.
Expression of PD-L1 is correlated with the severity of periodontitis in the mouse model of experimental periodontitis.
Blockade of TGFbeta (show TGFB1 ELISA Kits) downregulated PD-1 (show PDCD1 ELISA Kits) and PD-L1 expression and precipitated graft rejection.
Loss of Cdk5 (show CDK5 ELISA Kits) results in persistent expression of the PD-L1 transcriptional repressors, the interferon (show IFNA ELISA Kits) regulatory factors IRF2 (show IRF2 ELISA Kits) and IRF2BP2 (show IRF2BP2 ELISA Kits), which likely leads to reduced PD-L1 expression on tumors.
The endogenous PD-1 (show PDCD1 ELISA Kits)/PD-L pathway does not limit acute experimental foreign antigen-induced circulating immune complex glomerulonephritis.
addition to inhibiting T cells, hepatic stellate cells (HSCs) concurrently inhibit B cells via PD-L1; this direct B cell-inhibitory activity of HSCs should contribute to the mechanism by which HSCs maintain the liver's immune homeostasis
The results demonstrated that blockade of PD-1 (show PDCD1 ELISA Kits)/B7H1 pathway could promote mouse NK cells to kill the GL261GSCs, and the PD-1 (show PDCD1 ELISA Kits)-inhibited NK cells could be a feasible immune therapeutic approach against Glioblastoma multiforme.
These findings provide evidence for a novel immune escape mechanism during acute retroviral infection based on PD-L1 expression levels on virus infected target cells
These results suggest a novel and specific role for PspA (show SFTPA1 ELISA Kits) in modulating immune responses against S. pneumoniae by regulating PD-L1 expression.
The B7-H1 and B7-DC (show PDCD1LG2 ELISA Kits) staining was located in areas of the tissue that were identified.
PD-L1 expression was not prognostic in the overall cohort. PD-L1 expression in primary tumor and matched nodal specimens were highly concordant. The observed survival benefit in N2 disease requires confirmation
our study is the first and largest study to demonstrate overexpression of a targetable checkpoint protein, PD-L1 in metaplastic breast carcinoma
We found that high PD-L1 expression was a poor prognostic factor in the smokers with lung adenocarcinomaor the patients with wild-type EGFR (show EGFR ELISA Kits), whereas it was not the case in those who never smoked or those with EGFR (show EGFR ELISA Kits) mutation, implying the importance of adenocarcinoma driver mutations and etiology.
this study shows that serum PD-L1 may reflect sepsis disease severity, and serve as an independent prognostic factor for 28-days mortality
in a population of patients with non-small-cell lung cancer, the pattern of PD-L1 expression was heterogeneous, represented by two distinct cell types: the tumor cell (higher frequency) and IICs (lowest frequency). Positive PD-L1 expression was observed in 37.9% of tumor cells and in IICs of 24.3% of tumors.
The mRNA expression of PD-L1 in primary nephrectomy specimens revealed no significant association with unfavourable clinical parameters. Interestingly, though, a positive correlation with patient survival was found (HR=0,59, p=0,006).
Case Report: Metastatic lymphoepithelioma-like hepatocellular carcinoma is associated with PD-L1 expression.
expression of MDM2 (show MDM2 ELISA Kits), somatostatin (show SST ELISA Kits) receptor 2A, and PD-L1 in follicular dendritic cell sarcoma
In triple-negative breast cancer, stromal PD-L1 expression was associated with better disease-free survival.
role of programmed death ligand-1 (PD-L1) during porcine circovirus type 2 (PCV2) infection and porcine circovirus associated diseases (PCVAD) development
These data suggest that overexpression of PD-L1 and PD-L2 (show PDCD1LG2 ELISA Kits) mRNA is one mechanism by which immunosupression of postweaning multisystemic wasting syndrome pigs occurs.
Retinal PLD1 expression is enhanced in radial fibers of Muller cells with age. This finding suggests that PLD1 plays an important role in signal transduction of glial cells and neuronal cells in the retina.
A porcine PD-L1 molecule was cloned using RACE (rapid amplification of cDNA ends) technology and sequenced (GenBank # AY837780); it showed high sequence homology with human PD-L1.
This study provides novel information for the understanding of signalling through PD-L1.
Involved in the costimulatory signal essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
, CD274 antigen
, programmed cell death 1 ligand 1
, programmed cell death ligand 1
, B7 homolog 1
, PDCD1 ligand 1
, programmed death ligand 1