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Involved in the costimulatory signal essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Additionally we are shipping PD-L1 Antibodies (328) and PD-L1 Proteins (71) and many more products for this protein.
Showing 10 out of 42 products:
Human PD-L1 ELISA Kit for Sandwich ELISA - ABIN577883
Atesoglu, Tarkun, Demirsoy, Geduk, Mehtap, Batman, Kaya, Cekmen, Gulbas, Hacıhanefioglu: Soluble Programmed Death 1 (PD-1) Is Decreased in Patients With Immune Thrombocytopenia (ITP): Potential Involvement of PD-1 Pathway in ITP Immunopathogenesis. in Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 2014
PD-1 (show PDCD1 ELISA Kits)/PD-L1 plays a crucial role in maintaining immune tolerance induced by UVB-iDCs, as well as in actively controlling effector T cells specific to alloantigens.
Data show that Qiyusanlong decoction (QYSL) can moderately inhibit the growth of the transplanted tumor by decreasing programmed death 1 (show PDCD1 ELISA Kits) and programmed death ligand 1 (PD-1 (show PDCD1 ELISA Kits)/PD-L1) level.
Expression of PD-L1 is correlated with the severity of periodontitis in the mouse model of experimental periodontitis.
Blockade of TGFbeta (show TGFB1 ELISA Kits) downregulated PD-1 (show PDCD1 ELISA Kits) and PD-L1 expression and precipitated graft rejection.
Loss of Cdk5 (show CDK5 ELISA Kits) results in persistent expression of the PD-L1 transcriptional repressors, the interferon (show IFNA ELISA Kits) regulatory factors IRF2 (show IRF2 ELISA Kits) and IRF2BP2 (show IRF2BP2 ELISA Kits), which likely leads to reduced PD-L1 expression on tumors.
The endogenous PD-1 (show PDCD1 ELISA Kits)/PD-L pathway does not limit acute experimental foreign antigen-induced circulating immune complex glomerulonephritis.
addition to inhibiting T cells, hepatic stellate cells (HSCs) concurrently inhibit B cells via PD-L1; this direct B cell-inhibitory activity of HSCs should contribute to the mechanism by which HSCs maintain the liver's immune homeostasis
The results demonstrated that blockade of PD-1 (show PDCD1 ELISA Kits)/B7H1 pathway could promote mouse NK cells to kill the GL261GSCs, and the PD-1 (show PDCD1 ELISA Kits)-inhibited NK cells could be a feasible immune therapeutic approach against Glioblastoma multiforme.
These findings provide evidence for a novel immune escape mechanism during acute retroviral infection based on PD-L1 expression levels on virus infected target cells
These results suggest a novel and specific role for PspA (show SFTPA1 ELISA Kits) in modulating immune responses against S. pneumoniae by regulating PD-L1 expression.
Our data confirmed that PD-L1 could be an important marker for prognostic stratification and for planning immune checkpoint inhibitors therapies in patients with TNBC.
PD-L1 expression in chromophobe renal cell carcinoma
PD-1 (show PDCD1 ELISA Kits) and PD-L1 expressions are up to 30 % of the cases with sarcomas. It may be rational to target programmed death pathway in Kaposi sarcoma, pleomorphic sarcoma and peripheral nerve sheath tumors. Strong expression of PD-1 (show PDCD1 ELISA Kits)/PD-L1 in cases with previous giant cell bone tumor has been found to be interesting and must be studied in giant cell tumor samples.
this study describes a novel mechanism for trophoblastic cells to create a tolerogenic feto-maternal interface by upregulating PD-L1 in syncytiotrophoblast and in intermediate trophoblast
Upregulation of PD-L1 is associated with chemotherapy response in pancreatic cancer.
PD-1 (show PDCD1 ELISA Kits) and PD-L1 protein expression and their correlation with tumor-in fi ltrating lymphocytes (TILs), and association with survival in non-small cell lung cancer, were examined.
this study shows that PD-L1 expression in tumor cells markedly increased in non-small-cell lung cancer patients after gefitinib treatment
over-expression of PD-1 (show PDCD1 ELISA Kits) in subsets of vascular anomalies, while PD-L1 was negative
PD-L1 expression in ccRCC is associated with parameters of aggressiveness, as well as with poor overall survival, even though PD-L1 status was not identified as a significant independent prognostic parameter
The results demonstrated significantly lower expression of PD-1 (show PDCD1 ELISA Kits) and PD-L1 in chronic ITP (show ITPA ELISA Kits) patients compared with healthy individuals.
role of programmed death ligand-1 (PD-L1) during porcine circovirus type 2 (PCV2) infection and porcine circovirus associated diseases (PCVAD) development
These data suggest that overexpression of PD-L1 and PD-L2 (show PDCD1LG2 ELISA Kits) mRNA is one mechanism by which immunosupression of postweaning multisystemic wasting syndrome pigs occurs.
Retinal PLD1 expression is enhanced in radial fibers of Muller cells with age. This finding suggests that PLD1 plays an important role in signal transduction of glial cells and neuronal cells in the retina.
A porcine PD-L1 molecule was cloned using RACE (rapid amplification of cDNA ends) technology and sequenced (GenBank # AY837780); it showed high sequence homology with human PD-L1.
This study provides novel information for the understanding of signalling through PD-L1.
Involved in the costimulatory signal essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
, CD274 antigen
, programmed cell death 1 ligand 1
, programmed cell death ligand 1
, B7 homolog 1
, PDCD1 ligand 1
, programmed death ligand 1