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anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) Antibodies

CDH1 is a classical cadherin from the cadherin superfamily. Additionally we are shipping E-cadherin Kits (95) and E-cadherin Proteins (40) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CDH1 444901  
CDH1 12550 P09803
CDH1 999 P12830
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Top anti-E-cadherin Antibodies at antibodies-online.com

Showing 10 out of 685 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB 100 μL Log in to see 3 to 7 Days
$269.50
Details
Cow Rabbit Un-conjugated IF, IHC, WB WB Suggested Anti-CDH1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 293T cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IHC (p) 0.5 mL Log in to see 10 to 12 Days
$589.05
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated FACS, WB Western blot analysis of CDH1 Antibody (N-term) (ABIN388278) in 293 cell line lysates (35 µg/lane). CDH1 (arrow) was detected using the purified polyclonal antibody (1:60 dilution). Western blot analysis of CDH1 (arrow) using rabbit polyclonal CDH1 Antibody (N-term) (ABIN388278).293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the CDH1 gene (Lane 2) (Origene Technologies). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, WB Western blot analysis of CDH1 Antibody (C-term) (ABIN388279) in A375 cell line lysates (35 µg/lane). CDH1 (arrow) was detected using the purified polyclonal antibody (1:60 dilution). Western blot analysis of CDH1 (arrow) using rabbit polyclonal CDH1 Antibody (C-term) (ABIN388279). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the CDH1 gene (Lane 2) (Origene Technologies). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IHC (fro), IF, IHC (p), WB Immunohistochemistry on Paraffin-Embedded Sections of small intestine. 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Mouse Un-conjugated ELISA, WB Figure 1: Western blot analysis using CDH1 mouse mAb against LNCAP (1) ,A431 (2), DU145 (3), PC-3 (4), PC-12 (5) and T47D (6) cell lysate. 100 μL Log in to see 3 to 4 Days
$393.80
Details
Human Mouse Un-conjugated FACS, IHC, ELISA, WB Figure 1: Flow cytometric analysis of Hela cells using CDH1 mouse mAb (green) and negative control (purple) . Figure 2: Immunohistochemical analysis of paraffin-embedded gastric cancer tissues (left) and lung cancer tissues (right) using CDH1 mouse mAb with DAB staining. 100 μL Log in to see 3 to 4 Days
$393.80
Details

CDH1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-E-cadherin Antibodies

  1. Human Monoclonal E-cadherin Primary Antibody for ELISA, WB - ABIN969037 : Barrett, Lee, Lees, Prescott, Anderson, Phillips, Wesley, Parnell, Zhang, Drummond, Nimmo, Massey, Blaszczyk, Elliott, Cotterill, Dallal, Lobo, Mowat, Sanderson, Jewell, Newman, Edwards, Ahmad et al.: Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region. ... in Nature genetics 2009 (PubMed)
    Show all 3 references for ABIN969037

  2. Human Monoclonal E-cadherin Primary Antibody for FACS, IHC - ABIN969036 : Wang, Yao, Zhang, Zhang, Zhao: [Expression and significance of CD147 and E-cadherin in human gastric carcinoma]. in Zhonghua zhong liu za zhi [Chinese journal of oncology] 2009 (PubMed)
    Show all 3 references for ABIN969036

  3. Human Polyclonal E-cadherin Primary Antibody for EIA, WB - ABIN356994 : Mansouri, Spurr, Goodfellow, Kemler: Characterization and chromosomal localization of the gene encoding the human cell adhesion molecule uvomorulin. in Differentiation; research in biological diversity 1988 (PubMed)
    Show all 3 references for ABIN356994

  4. Human Polyclonal E-cadherin Primary Antibody for FACS, WB - ABIN388278 : Hsu, Chen, Chou, Tang, Chen, Wilkins, Ellory, Shen: KCl cotransporter-3 down-regulates E-cadherin/beta-catenin complex to promote epithelial-mesenchymal transition. in Cancer research 2007 (PubMed)
    Show all 3 references for ABIN388278

  5. Human Monoclonal E-cadherin Primary Antibody for IHC (p) - ABIN180686 : Bukholm, Nesland, Børresen-Dale: Re-expression of E-cadherin, alpha-catenin and beta-catenin, but not of gamma-catenin, in metastatic tissue from breast cancer patients [seecomments]. in The Journal of pathology 2000 (PubMed)
    Show all 3 references for ABIN180686

  6. Human Polyclonal E-cadherin Primary Antibody for EIA, WB - ABIN356995 : Knudsen, Wheelock: Plakoglobin, or an 83-kD homologue distinct from beta-catenin, interacts with E-cadherin and N-cadherin. in The Journal of cell biology 1992 (PubMed)
    Show all 2 references for ABIN356995

  7. Human Monoclonal E-cadherin Primary Antibody for IHC (fro), IF - ABIN1106274 : Umbas, Schalken, Aalders, Carter, Karthaus, Schaafsma, Debruyne, Isaacs: Expression of the cellular adhesion molecule E-cadherin is reduced or absent in high-grade prostate cancer. in Cancer research 1992 (PubMed)
    Show all 2 references for ABIN1106274

  8. Human Polyclonal E-cadherin Primary Antibody for IF (p), IHC (p) - ABIN1387847 : Chen, Cheng, Chen, Sue, Liu, Cheng, Hsu, Chen: MicroRNA-328 inhibits renal tubular cell epithelial-to-mesenchymal transition by targeting the CD44 in pressure-induced renal fibrosis. in PLoS ONE 2014 (PubMed)
    Show all 2 references for ABIN1387847

  9. Cow (Bovine) Polyclonal E-cadherin Primary Antibody for IF, IHC - ABIN2784498 : Onder, Gupta, Mani, Yang, Lander, Weinberg: Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways. in Cancer research 2008 (PubMed)

More Antibodies against E-cadherin Interaction Partners

Xenopus laevis Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) interaction partners

  1. E-cadherin has a role in cranial neural crest migration in Xenopus laevis

  2. the switch from E- to N-cadherin (show CDH2 Antibodies) during epithelial-mesenchymal transition is essential for acquisition of Contact inhibition of locomotion behavior.

  3. Moderate attenuation of C-cadherin function affects cell adhesion but not gastrulation.

  4. Because paraxial protocadherin and C-cadherin do not directly interact nor form a joint complex with Fz7, Wnt-11 triggers formation of two distinct complexes that act in parallel to reduce cell adhesion by hampering clustering of C-cadherin.

  5. The functional and physical relationships between PAPC, FLRT3, and C-cadherin, was investigated.

  6. PAPC mediates these functions by down-regulating the adhesion activity of C-cadherin.

  7. Results suggest that the basis for cell segregation during morphogenesis does not map exclusively to protein-level differences in E-, N-, or C-cadherin adhesion.

  8. G-protein-coupled receptors control cortical actin assembly by controlling the amount of cadherin expressed on the cell surface.

  9. Two stage cadherin kinetics require multiple extracellular domains but not the cytoplasmic region

  10. Data show that the intracellular domain of PAPC (Protocadherin) interacts with Sprouty (Spry), and upon binding to PAPC, Spry function is inhibited and PCP signaling is enhanced.

Mouse (Murine) Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) interaction partners

  1. Demonstrate that HBx-HCCR-E-cadherin regulation pathway might play an important role in HBV-induced hepatocarcinogenesis.

  2. E-cadherin expression regulates inflammatory mediators in macrophages.

  3. Increased expression of E-cadherin binds to and sequesters beta-catenin (show CTNNB1 Antibodies) away from downstream Wnt (show WNT2 Antibodies) signaling proteins.

  4. Results suggest a regulatory function of E-cadherin that modulates Nrg1 (show NRG1 Antibodies) signaling and promotes Schwann cell myelin formation

  5. Both catalytic and non-catalytic APC (show APC Antibodies)/C-Fzr1/Cdh1 (show FZR1 Antibodies)-mediated activities of PTEN (show PTEN Antibodies) are required for stalk cells' proliferative arrest. Findings implicate the PTEN (show PTEN Antibodies)-APC (show APC Antibodies)/C-Fzr1/Cdh1 (show FZR1 Antibodies) hub in angiogenesis.

  6. we conclude that APC (show APC Antibodies)/C(Cdh1) controls CK1 (show KRT1 Antibodies) delta levels to balance proliferation and cell-cycle exit in the developing CNS

  7. During submandibular gland development, a Hippo pathway effector, TAZ (show TAZ Antibodies), becomes increasingly phosphorylated and associated with E-cadherin and alpha-catenin (show CTNNA1 Antibodies), consistent with the activation of Hippo signaling. (Hippo)

  8. Vangl2 (show VANGL2 Antibodies) regulates E-cadherin in epithelial cells.

  9. Pkd1 (show PKD1 Antibodies) mutation or deletion leads to the activation of Galpha12 (show GNA12 Antibodies), which promotes the maturation of ADAM10 (show ADAM10 Antibodies) that increases the shedding of E-cadherin in kidney epithelial cells.

  10. Our results provide novel insights into identification of novel distal enhancer elements regulating E-cadherin expression

Human Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) interaction partners

  1. E-cadherin expression is down-regulated in colon cancer cells through inactivation of UTX (show KDM6A Antibodies).

  2. The present study therefore indicated that IL-6 (show IL6 Antibodies) promoted the process of EMT (show ITK Antibodies) in HIBECs as characterized by increased migration and invasion of HIBECs and the typical changes in mRNA and protein expression of the EMT (show ITK Antibodies) markers E-cadherin and vimentin (show VIM Antibodies).

  3. Results show that telomere shortening is closely associated with severity of Helicobacter pylori-induced gastritis and CDH1 methylation status.

  4. Findings indicated that HIF-2alpha (show EPAS1 Antibodies) promotes epithelial-mesenchymal transition in pancreatic cancer by regulating Twist2 (show TWIST2 Antibodies) binding to the promoter of E-cadherin.

  5. CDH1 promoter methylation can be a potential biomarker in ovarian cancer risk prediction. [meta-analysis]

  6. As a consequence, Slug transcription is down-regulated relieving A549 cells from Slug-mediated repression of E-cadherin transcription, thereby diminishing the metastatic potential of these oncogenic Ras-expressing NSCLC cells

  7. Low CDH1 contributes to endometrial cancer progression.

  8. UHRF1 (show UHRF1 Antibodies) promotes osteosarcoma cell invasion by downregulating the expression of Ecadherin and increasing epithelialtomesenchymal transition in an Rb1dependent manner.

  9. PTTG2 induces psoriasis by regulating epidermal expression of vimentin (show VIM Antibodies) and E-cadherin.

  10. Evaluation of FoxC2 (show FOXC2 Antibodies) expression, alone or in combination with E-cadherin expression, may help to stratify non-small cell lung cancer patients for risk of disease progression, pointing to this EMT (show ITK Antibodies) regulator as a potential prognostic marker

Pig (Porcine) Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) interaction partners

  1. E-cadherin mRNA/protein were up-regulated in all flutamide-treated corpus luteum of mid- and late pregnancy.

  2. In pig kidney, strong E-cadherin expression was observed in the basolateral plasma membrane of the tubular epithelial cells. E-cadherin immunolabeling was not detected in glomeruli or blood vessels of pig kidney.

  3. Localisation of NANOG (show NANOG Antibodies), OCT4 (show POU5F1 Antibodies), and E-CADHERIN in porcine pre- and peri (show PLIN1 Antibodies)-implantation embryos.

  4. The epiblast expressed epithelial markers, MUC1 (show MUC1 Antibodies) and E-CADHERIN, and the pluripotency markers, DNMT3B (show DNMT3B Antibodies) and CRIPTO (show TDGF1 Antibodies).

Cow (Bovine) Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) interaction partners

  1. Transfection of zygotes with 100 and 200 nM E-cadherin siRNA led to a 72 and 38% reduction, respectively, in E-cadherin mRNA relative abundance in Day 7 blastocysts compared with controls.

  2. E-cadherin and beta-catenin (show CTNNB1 Antibodies) were distributed not only at the cell to cell boundary but throughout the cytoplasm in binucleate trophoblast cells

  3. Results describe the effect of suppression of connexin 43 (show GJA1 Antibodies) and E-cadherin on the development, mRNA and protein expression of bovine blastocysts cultured in vitro or in vivo.

Zebrafish Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) interaction partners

  1. E-cadherin mRNA coinjection demonstrated the specificity of cdh1 morpholino oligonucleotides-induced defects

  2. Results suggest that Wnt11 (show WNT11 Antibodies) controls tissue morphogenesis by modulating E-cadherin-mediated cell cohesion through Rab5c (show Rab5c Antibodies), a novel mechanism of Wnt (show WNT2 Antibodies) signaling in gastrulation.

E-cadherin (CDH1) Antigen Profile

Protein Summary

This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites.

Gene names and symbols associated with CDH1

  • cadherin 3, type 1, P-cadherin (placental) (cdh3-a) antibody
  • Aerobic running capacity QTL 1 (Arunc1) antibody
  • cadherin 1 (Cdh1) antibody
  • cadherin 1, type 1, E-cadherin (epithelial) (CDH1) antibody
  • cadherin 1, type 1, E-cadherin (epithelial) (Cdh1) antibody
  • cadherin 1, type 1, E-cadherin (epithelial) (cdh1) antibody
  • E-cadherin-like (LOC100356548) antibody
  • si:busm1-180o5.2 (si:busm1-180o5.2) antibody
  • AA960649 antibody
  • arc-1 antibody
  • Arc1 antibody
  • b-cadherin antibody
  • cadherin-1 antibody
  • cd324 antibody
  • cdh1 antibody
  • cdh1-a antibody
  • cdhc-A antibody
  • cdhe antibody
  • cdhp antibody
  • E-cad antibody
  • E-cadherin antibody
  • ecad antibody
  • hjmd antibody
  • L-CAM antibody
  • LCAM antibody
  • pcad antibody
  • si:dz180o5.2 antibody
  • Um antibody
  • UVO antibody
  • uvomorulin antibody
  • xb-cad antibody
  • XB-cadherin antibody
  • XBcad antibody
  • xcdh1 antibody
  • XTCAD-1 antibody

Protein level used designations for CDH1

C-cadherin (EP-cadherin) , EP-cadherin , cadherin 1, type 1, E-cadherin (epithelial) , ARC-1 , E-cadherin , cadherin-1 , epithelial cadherin , uvomorulin , CAM 120/80 , E-Cadherin , cadherin 1, E-cadherin (epithelial) , calcium-dependent adhesion protein, epithelial , cell-CAM 120/80 , L-CAM , liver cell adhesion molecule , liver cell adhesion protein , xTCAD-1 , Epithelial cadherin , hypothetical protein LOC368517

GENE ID SPECIES
394290 Xenopus laevis
444901 Rattus norvegicus
12550 Mus musculus
83502 Rattus norvegicus
999 Homo sapiens
442858 Canis lupus familiaris
100048953 Sus scrofa
282637 Bos taurus
415860 Gallus gallus
101095391 Felis catus
101119747 Ovis aries
100726210 Cavia porcellus
100337618 Xenopus laevis
100174439 Pongo abelii
100356548 Oryctolagus cuniculus
368517 Danio rerio
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