E-cadherin antibody (AA 381-480)

Catalog No. ABIN560274

Cited in 1 publication. The Mouse Monoclonal anti-E-cadherin antibody (Clone 3F4) (ABIN560274) specifically detects E-cadherin in WB, ELISA, IHC (p) and PLA. The antibody is reactive with Human samples.

Quick Overview for E-cadherin antibody (AA 381-480) (ABIN560274)

Target: E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This E-cadherin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Proximity Ligation Assay (PLA)

Clone: 3F4

Product Details anti-E-cadherin Antibody

Binding Specificity: AA 381-480

Purpose: Mouse monoclonal antibody raised against a partial recombinant CDH1.

Sequence: KGQVPENEAN VVITTLKVTD ADAPNTPAWE AVYTILNDDG GQFVVTTNPV NNDGILKTAK GLDFEAKQQY ILHVAVTNVV PFEVSLTTST ATVTVDVLDV

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: CDH1 (NP_004351, 381 a.a. ~ 480 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-E-cadherin antibody (ABIN560274)

Wen, Chen, Chen, Chuang, Yang, Chow: "Development of an AlphaLISA assay to quantify serum core-fucosylated E-cadherin as a metastatic lung adenocarcinoma biomarker." in: Journal of proteomics, Vol. 75, Issue 13, pp. 3963-76, (2012) (PubMed).

Target Details for E-cadherin

Target: E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))

Alternative Name: CDH1

Background: Full Gene Name: cadherin 1, type 1, E-cadherin (epithelial)
Synonyms: Arc-1,CD324,CDHE,ECAD,LCAM,UVO

Gene ID: 999

NCBI Accession: NM_004360

Pathways: WNT Signaling, Sensory Perception of Sound, Cell-Cell Junction Organization, Tube Formation