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CNR1 encodes one of two cannabinoid receptors. Additionally we are shipping CNR1 Kits (37) and CNR1 Proteins (7) and many more products for this protein.
Showing 10 out of 135 products:
Human Polyclonal CNR1 Primary Antibody for WB - ABIN1881140
Van Laere, Casteels, Dhollander, Goffin, Grachev, Bormans, Vandenberghe: Widespread decrease of type 1 cannabinoid receptor availability in Huntington disease in vivo. in Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2010
Show all 4 references for ABIN1881140
Human Polyclonal CNR1 Primary Antibody for ELISA, WB - ABIN185484
Ledent, Valverde, Cossu, Petitet, Aubert, Beslot, Böhme, Imperato, Pedrazzini, Roques, Vassart, Fratta, Parmentier: Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice. in Science (New York, N.Y.) 1999
genetic or chemical inhibition of cannabinoid receptor (Cnr (show PCDHA1 Antibodies)) activity disrupts liver development and metabolic function in zebrafish.
CB1 function is required in the early embryo for axonal growth and fasciculation.
CNR1 polymorphisms are not associated with obesity and metabolic disorders, including insulin (show INS Antibodies) resistance, in PCOS women.
data support an association between endocannabinoid system activity (cb1) and alcoholism.
Human lung-resident macrophages express CB1 and CB2 (show CNR2 Antibodies) receptors whose activation inhibits the release of angiogenic and lymphangiogenic factors
Studies indicate that crosstalk between cannabinoid receptor type 1 (CB1) and transient receptor potential vanilloid 1 (TRPV1 (show TRPV1 Antibodies)) modulates pain and inflammation in arthritis.
CNR1 polymorphism and child physical abuse GxE interaction predicts adult PTSD threat symptoms.
CNR1 variants are associated with structural and functional brain changes after first episode psychosis; the cannabinoid pathway is associated with disease progression over time.
cannabinoid receptor 1-G allele carriers who were also cannabis users had greater functional connectivity in the left ventrolateral prefrontal cortex and reduced working memory behavioral accuracy
Resistance exercise down-regulates skeletal muscle CB1 expression.
Treatment with the CB1 neutral antagonist tetrahydrocannabivarin increases neural responding to rewarding and aversive stimuli.
CB1 immunoreactivity was markedly stronger in preeclamptic samples compared to normal pregnancies
cannabidiol causes vasorelaxation of human mesenteric arteries via activation of cannabinoid receptor 1
These results demonstrate that the CB1R-Ih pathway in the hippocampus is obligatory for the action of cannabinoids on long-term potentiation and spatial memory formation.
Study showed a pivotal role of CB1r in the regulation of sensorimotor gating processes and demonstrated that the preattentional deficit showed by CB1KO mice could be improved by methylphenidate but not with haloperidol or risperidone administration
The CB1 cannabinoid receptor signals striatal neuroprotection via a PI3K/Akt (show AKT1 Antibodies)/mTORC1/BDNF (show BDNF Antibodies) pathway.
CB1 has a major role in the activation of myofibroblasts.
Constantly elevated levels of 2-arachidonyl glycerol induce severe desensitization of intestinal CB1 receptors.
Important role of CB1R in cortical map formation and impact in the development of primary visual cortex neurons. Results could possibly explain neuronal mechanisms involved in changes of visual perception.
This study demonstrated that the CB1 receptor tunes dorsal telencephalic progenitor proliferation by sustaining the transcriptional activity of the Pax6 (show PAX6 Antibodies)-Tbr2 (show EOMES Antibodies) axis via the mTORC1 pathway.
Genetic and pharmacological study indicates that CB1R are not necessary for adaptation of the HPA (show HPSE Antibodies) axis and other variables to repeated exposure to stress either in mice or rats
CB1 receptor expression decreased after traumatic brain injury and was negatively correlated with edema formation and behavioral impairments.
The endocannabinoid system in renal cells: regulation of sodium transport by CB1 receptors through distinct cell signaling pathways
CB1 functionality increased with development at both central and peripheral level.
This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.
cannabinoid receptor 1 (brain)
, cannabinoid receptor (brain)
, cannabinoid receptor 1
, cannabinoid receptor 1-like
, central cannabinoid receptor
, brain-type cannabinoid receptor
, striatal cannabinoid receptor type 1 protein
, cannabinoid 1 receptor
, CB1 cannabinoid receptor
, cannabinoid receptor CB-1
, cannabinoid receptor 1/CB1