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CNR1 encodes one of two cannabinoid receptors. Additionally we are shipping CNR1 Kits (37) and CNR1 Proteins (7) and many more products for this protein.
Showing 10 out of 136 products:
Human Polyclonal CNR1 Primary Antibody for WB - ABIN1881140
Van Laere, Casteels, Dhollander, Goffin, Grachev, Bormans, Vandenberghe: Widespread decrease of type 1 cannabinoid receptor availability in Huntington disease in vivo. in Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2010
Show all 4 references for ABIN1881140
Human Polyclonal CNR1 Primary Antibody for ELISA, WB - ABIN185484
Ledent, Valverde, Cossu, Petitet, Aubert, Beslot, Böhme, Imperato, Pedrazzini, Roques, Vassart, Fratta, Parmentier: Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice. in Science (New York, N.Y.) 1999
genetic or chemical inhibition of cannabinoid receptor (Cnr (show PCDHA1 Antibodies)) activity disrupts liver development and metabolic function in zebrafish.
CB1 function is required in the early embryo for axonal growth and fasciculation.
Novel finding of the present study is the association of the mutant groups of CNR1 genotypes with lower levels of triglycerides and higher levels of HDL (show HSD11B1 Antibodies)-cholesterol than the wild-type group.
The present study reports an association of the G1359A and A1359A CNR1 genotypes with lower levels of triglycerides and higher levels of HDL (show HSD11B1 Antibodies)-cholesterol in obese females.
In the adult human ependyma, which usually shows central canal absence, CB1 may play a different role by modulating astrocyte functions
Induction of apoptosis was mediated via CB1 as well as CB2 (show CNR2 Antibodies), and expression of CB receptors was a prerequisite for therapy response in our models.
CNR1 polymorphisms are not associated with obesity and metabolic disorders, including insulin (show INS Antibodies) resistance, in PCOS women.
data support an association between endocannabinoid system activity (cb1) and alcoholism.
Human lung-resident macrophages express CB1 and CB2 (show CNR2 Antibodies) receptors whose activation inhibits the release of angiogenic and lymphangiogenic factors
Studies indicate that crosstalk between cannabinoid receptor type 1 (CB1) and transient receptor potential vanilloid 1 (TRPV1 (show TRPV1 Antibodies)) modulates pain and inflammation in arthritis.
CNR1 polymorphism and child physical abuse GxE interaction predicts adult PTSD threat symptoms.
CNR1 variants are associated with structural and functional brain changes after first episode psychosis; the cannabinoid pathway is associated with disease progression over time.
Study showed that basolateral amygdala alpha2-adrenergic receptors may be involved in context- but not tone-dependent fear memory impairment induced by activation of CB1 receptors
Adult female Cnr1 knockouts do not exhibit increased anxiety as in adult male Cnr1 knockouts; adult female ovariectomy does not increase anxiety-like behavior in Cnr1 knockouts; Cnr1 antagonism increases anxiety-like behavior in C57BL/6J mice
Results provide clear evidence that the endocannabinoid system, through CB1 receptors, participates in the different stages of short- and long-term memory-related behavior
CB1 receptor and mTORC1 signalling pathways interact to modulate glucose homeostasis in mice
cannabidiol causes vasorelaxation of human mesenteric arteries via activation of cannabinoid receptor 1
These results demonstrate that the CB1R-Ih pathway in the hippocampus is obligatory for the action of cannabinoids on long-term potentiation and spatial memory formation.
Study showed a pivotal role of CB1r in the regulation of sensorimotor gating processes and demonstrated that the preattentional deficit showed by CB1KO mice could be improved by methylphenidate but not with haloperidol or risperidone administration
The CB1 cannabinoid receptor signals striatal neuroprotection via a PI3K/Akt (show AKT1 Antibodies)/mTORC1/BDNF (show BDNF Antibodies) pathway.
CB1 has a major role in the activation of myofibroblasts.
Constantly elevated levels of 2-arachidonyl glycerol induce severe desensitization of intestinal CB1 receptors.
The endocannabinoid system in renal cells: regulation of sodium transport by CB1 receptors through distinct cell signaling pathways
CB1 functionality increased with development at both central and peripheral level.
This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.
cannabinoid receptor 1 (brain)
, cannabinoid receptor (brain)
, cannabinoid receptor 1
, cannabinoid receptor 1-like
, central cannabinoid receptor
, brain-type cannabinoid receptor
, striatal cannabinoid receptor type 1 protein
, cannabinoid 1 receptor
, CB1 cannabinoid receptor
, cannabinoid receptor CB-1
, cannabinoid receptor 1/CB1