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CNR1 encodes one of two cannabinoid receptors. Additionally we are shipping CNR1 Kits (29) and CNR1 Proteins (7) and many more products for this protein.
Showing 10 out of 145 products:
Human Polyclonal CNR1 Primary Antibody for WB - ABIN1881140
Van Laere, Casteels, Dhollander, Goffin, Grachev, Bormans, Vandenberghe: Widespread decrease of type 1 cannabinoid receptor availability in Huntington disease in vivo. in Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2010
Show all 4 references for ABIN1881140
Human Polyclonal CNR1 Primary Antibody for ELISA, WB - ABIN185484
Ledent, Valverde, Cossu, Petitet, Aubert, Beslot, Böhme, Imperato, Pedrazzini, Roques, Vassart, Fratta, Parmentier: Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice. in Science (New York, N.Y.) 1999
Anandamide, through CB1 and TRPV1 (show TRPV1 Antibodies) activation, is involved in sperm release from the oviductal reservoir.
genetic or chemical inhibition of cannabinoid receptor (Cnr (show PCDHA1 Antibodies)) activity disrupts liver development and metabolic function in zebrafish.
CB1 function is required in the early embryo for axonal growth and fasciculation.
Data indicate that mobile tongue squamous cell carcinoma (SCC (show CYP11A1 Antibodies)) patients presenting enhanced cannabinoid receptors CB1R, CB2R (show CNR2 Antibodies), or concomitant CB1R/CB2R (show CNR2 Antibodies) expression showed significantly longer overall and disease-free survival times compared to those with low expression.
This is the first demonstration that the fibroblasts of the muscular fasciae express CB1 and CB2 (show CNR2 Antibodies).
Epistatic interaction between the 1359 G/A polymorphism of the CNR1 gene and the DRD2 (show DRD2 Antibodies) gene polymorphisms may be associated with cannabis addiction phenotype in a Turkish population.
in the group of all HD patients, a significantly higher incidence of GA genotype and lower incidence in GG genotype in the polymorphism rs806381s were revealed versus the control group (p = 0.04). It seems that polymorphisms of the CNR1 gene are not associated with uremic pruritus.
Results suggest that CNR1 SNP genotype is associated with increased total cholesterol and Myocardial Infarction.
this study presents the 2.8 A crystal structure of human CB1 in complex with AM6538, a stabilizing antagonist, synthesized and characterized for this structural study.
Novel finding of the present study is the association of the mutant groups of CNR1 genotypes with lower levels of triglycerides and higher levels of HDL (show HSD11B1 Antibodies)-cholesterol than the wild-type group.
The present study reports an association of the G1359A and A1359A CNR1 genotypes with lower levels of triglycerides and higher levels of HDL (show HSD11B1 Antibodies)-cholesterol in obese females.
In the adult human ependyma, which usually shows central canal absence, CB1 may play a different role by modulating astrocyte functions
Induction of apoptosis was mediated via CB1 as well as CB2 (show CNR2 Antibodies), and expression of CB receptors was a prerequisite for therapy response in our models.
CB1 receptor tolerance does not occur in aged mice pretreated with Delta(9)-tetrahydrocannabinol and in young adult mice treated with a low dose of the monoacylglycerol lipase (show MGLL Antibodies) inhibitor JZL 184.
CB1R expression contributes to the development of persistent mechanical hypersensitivity.
Findings suggest a minor role for the CB2 (show CNR2 Antibodies) receptor in the therapeutic effect of the cannabis-based medicine in AbetaPP/PS1 (show PSEN1 Antibodies) transgenic mice, but also constitute evidence of a link between CB2 (show CNR2 Antibodies) receptor and Abeta (show APP Antibodies) processing
Suggest that the CB1R is involved in auditory processing using CB1R knockout mice.
CB1 activation negatively impacts GLP-1R (show GLP1R Antibodies)-mediated insulin (show INS Antibodies) secretion.
Study showed that basolateral amygdala alpha2-adrenergic receptors may be involved in context- but not tone-dependent fear memory impairment induced by activation of CB1 receptors
Adult female Cnr1 knockouts do not exhibit increased anxiety as in adult male Cnr1 knockouts; adult female ovariectomy does not increase anxiety-like behavior in Cnr1 knockouts; Cnr1 antagonism increases anxiety-like behavior in C57BL/6J mice
Results provide clear evidence that the endocannabinoid system, through CB1 receptors, participates in the different stages of short- and long-term memory-related behavior
CB1 receptor and mTORC1 signalling pathways interact to modulate glucose homeostasis in mice
cannabidiol causes vasorelaxation of human mesenteric arteries via activation of cannabinoid receptor 1
The endocannabinoid system in renal cells: regulation of sodium transport by CB1 receptors through distinct cell signaling pathways
CB1 functionality increased with development at both central and peripheral level.
This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.
cannabinoid receptor 1 (brain)
, cannabinoid receptor (brain)
, cannabinoid receptor 1
, cannabinoid receptor 1-like
, central cannabinoid receptor
, brain-type cannabinoid receptor
, striatal cannabinoid receptor type 1 protein
, cannabinoid 1 receptor
, CB1 cannabinoid receptor
, cannabinoid receptor CB-1
, cannabinoid receptor 1/CB1