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CNR1 antibody (Cannabinoid Receptor 1) (Internal Region)

Details for Product anti-CNR1 Antibody No. ABIN185484, Supplier: Log in to see
Antigen
  • CNR1
  • LOC540382
  • CANN6
  • CB-R
  • CB1
  • CB1A
  • CB1K5
  • CB1R
  • CNR
  • SKR6R
  • cnr1-A
Epitope
Internal Region
30
18
15
13
11
8
4
4
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
118
54
41
5
5
2
2
1
1
1
1
Host
Goat
97
28
9
Clonality
Polyclonal
Conjugate
This CNR1 antibody is un-conjugated
5
5
5
4
4
4
1
1
1
1
1
1
1
1
1
Methode Type
Peptide ELISA
Application
ELISA, Western Blotting (WB)
108
69
25
18
11
10
9
4
3
1
1
Supplier
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Immunogen Peptide with sequence C-HTSEDGKVQVTRPDQ, from the internal region of the protein sequence according to NP_057167.2, NP_001153732.1, NP_001153731.1, NP_001153730.1, NP_001153698.1, NP_149421.1.
Blocking Peptide Blocking peptide for this product available: ABIN369216
Specificity This antibody is expected to recognise both reported isoforms. Isoform a (NP_057167.2, NP_001153732.1, NP_001153731.1, NP_001153730.1, NP_001153698.1) and isoform b (NP_149421.1).
Cross-Reactivity Rat (Rattus), Dog (Canine)
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name Cannabinoid Receptor 1 (CNR1 Antibody Abstract)
Background Synonyms: cannabinoid receptor 1 (brain), CNR1, HGNC:2159, CANN6, CB-R, CB1, CB1A, CB1K5, CNR, central cannabinoid receptor, RP1-23D17.1, CB1R, OTTHUMP00000016838, OTTHUMP00000016839, cannabinoid receptor 1
Gene ID 1268, 12801, 25248
NCBI Accession NP_001153732, NP_001153731, NP_001153730, NP_001153698, NP_149421, NP_057167
Application Notes ELISA: antibody detection limit dilution 1:32000.
Western blot: Approx 65 kDa band observed in Rat Brain lysates (calculated MW of 52.7 kDa according to Rat NP_036916.1 and 52.9 kDa according to Human NP_057167.2). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Porcella et al, Eur J Neurosci. 2000 Mar,12(3):1123-7. PMID: 10762343). Recommended concentration: 0.1-0.3 µg/mL.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Supplier Images
 image for anti-CNR1 antibody (Cannabinoid Receptor 1) (Internal Region) (ABIN185484) ABIN185484 (1µg/ml) staining of human brain lysate (35µg protein in RIPA buffer). Pri...
Background publications Ledent, Valverde, Cossu et al.: "Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice." in: Science (New York, N.Y.), Vol. 283, Issue 5400, pp. 401-4, 1999 (PubMed).