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anti-Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1) Antibodies

Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. Additionally we are shipping Chitinase 3-Like 1 (Cartilage Glycoprotein-39) Kits (65) and Chitinase 3-Like 1 (Cartilage Glycoprotein-39) Proteins (17) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CHI3L1 12654 Q61362
CHI3L1 1116 P36222
CHI3L1 89824 Q9WTV1
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Top anti-Chitinase 3-Like 1 (Cartilage Glycoprotein-39) Antibodies at antibodies-online.com

Showing 10 out of 67 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IF, WB WB Suggested Anti-CHI3L1 Antibody Titration: 0.2-1 ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Human Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p) HepG2 cells probed with Rabbit Anti-CHI3L1 Polyclonal Antibody  Alexa Fluor 488 Secondary 100 μL Log in to see 14 to 21 Days
$269.50
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$369.79
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$369.79
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB Western blot analysis of YKL-40 expression in HEK293T (A), Raw264.7 (B), H9C2 (C) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated ELISA   100 μg Log in to see 16 Days
$163.90
Details
Mouse Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of THP1 cell lines, using CHI3L1 antibody. 100 μL Log in to see 9 Days
$302.50
Details

CHI3L1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,


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Human , , ,
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Rat (Rattus)


Top referenced anti-Chitinase 3-Like 1 (Cartilage Glycoprotein-39) Antibodies

  1. Human Polyclonal CHI3L1 Primary Antibody for ELISA - ABIN1998531 : Rehli, Niller, Ammon, Langmann, Schwarzfischer, Andreesen, Krause: Transcriptional regulation of CHI3L1, a marker gene for late stages of macrophage differentiation. in The Journal of biological chemistry 2003 (PubMed)
    Show all 2 references for ABIN1998531

  2. Human Monoclonal CHI3L1 Primary Antibody for EIA, IHC (p) - ABIN356240 : Bonneh-Barkay, Bissel, Wang, Fish, Nicholl, Darko, Medina-Flores, Murphey-Corb, Rajakumar, Nyaundi, Mellors, Bowser, Wiley: YKL-40, a marker of simian immunodeficiency virus encephalitis, modulates the biological activity of basic fibroblast growth factor. in The American journal of pathology 2008 (PubMed)
    Show all 2 references for ABIN356240

  3. Cow (Bovine) Polyclonal CHI3L1 Primary Antibody for IF, WB - ABIN2784693 : Ober, Tan, Sun, Possick, Pan, Nicolae, Radford, Parry, Heinzmann, Deichmann, Lester, Gern, Lemanske, Nicolae, Elias, Chupp: Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function. in The New England journal of medicine 2008 (PubMed)

More Antibodies against Chitinase 3-Like 1 (Cartilage Glycoprotein-39) Interaction Partners

Mouse (Murine) Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1) interaction partners

  1. IL-18 (show IL18 Antibodies) is a potent stimulator of Chi3l1 and that Chi3l1 is an important mediator of IL-18 (show IL18 Antibodies)-induced inflammatory, fibrotic, alveolar remodeling, and cytotoxic responses.

  2. CHI3L1 is induced during fungal infection, and it regulated antifungal innate immune responses in the cornea.

  3. Astrocytic expression of chitinase 3-like protein 1 limits the extent of both astrocytic and microglial/macrophage facets of neuroinflammation.

  4. Results do not support a role of BRP (show GDF5 Antibodies)-39 in the pathogenesis of experimental autoimmune encephalitis.

  5. CHI3L1 was increased in plasma and brain tissue in experimental cerebral malaria, but targeted Chi3l1 deletion did not alter cytokine production or survival in this model.

  6. mechanism of BRP (show GDF5 Antibodies)-39 in bleomycin-induced pulmonary fibrosis

  7. Sem7a and its receptors regulate Chi3l1 in pulmonary melanoma metastasis

  8. Data show that IL-1 (show IL1A Antibodies)-induced transcriptin factor RelB (show RELB Antibodies)/NF-kappa B p50 (show NFKB1 Antibodies) Subunit complex formation was further promoted by oncostatin M (show OSM Antibodies) and that these complexes directly bound to the secreted protein cartilage glycoprotein 39 (YKL-40) promoter.

  9. These results indicate that catalytically inactive BRP (show GDF5 Antibodies)-39 and Ym1 (show CHI3L3 Antibodies) are constitutive genes in normal mouse lung.

  10. BRP (show GDF5 Antibodies)-39 is involved in repressing the M1 proinflammatory phenotype in hyperoxia, thereby deactivating inflammatory responses in macrophages and preventing neonatal lung injury.

Human Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1) interaction partners

  1. This review comprehensively analyzes recent data about expression pattern, and involvement of human YKL-40, YKL-39 (show CHI3L2 Antibodies) and SI-CLP (show CHID1 Antibodies) in cancer. [review]

  2. Increased mRNA level of CHI3L1 could be associated with the progression of astrocytoma and poor patient survival not only for glioblastoma, but for lower grade astrocytoma tumors as well.

  3. serum YKL-40 level in coronary artery disease patients was significantly higher than that in control subjects.

  4. Study suggests that a newly identified subgroup of SSEA (show MPST Antibodies)-4 and YKL-40 positive cells constitute a fraction of astroglial progenitors, and suggests the name SYPAP (SSEA (show MPST Antibodies)-4 and YKL-40 positive astroglial progenitors) for this particular population

  5. Serum YKL-40 level increases with severity of obstructive sleep apnea syndrome (OSAS). The findings suggest that YKL-40 may be a useful biomarker for inflammation in patients with OSAS.

  6. CHI3L1 is expressed during the process of differentiation and maturation of dendritic cells in time dependent manner, it could play a crucial role in the dendritic cells immune response.

  7. Neurogranin (show NRGN Antibodies) and YKL-40 are promising AD biomarkers, independent of and complementary to the established core Alzheimer's disease (AD) biomarkers, reflecting additional pathological changes in the course of AD

  8. Data show that the expression of chitinase 3-like 1 (cartilage glycoprotein-39) protein (CHI3L1) was higher in cancerous tissues than in normal tissues.

  9. The serum YKL-40 cutoff to identify beta-thalassemia major patients with liver cirrhosis or heart disease was determined.

  10. We identified five new biomarkers: GDF15 (show GDF15 Antibodies), osteonectin (show SPARC Antibodies), TRAP5, TWEAK (show TNFSF12 Antibodies), and YKL40 as being promising markers for monitoring bone metastases.

Cow (Bovine) Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1) interaction partners

  1. chitinase-like lectin, YKL-40, binds specifically to type I collagen and modulates the rate of type I collagen fibril formation

Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1) Antigen Profile

Protein Summary

Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 family of chitinases includes eight human family members. This gene encodes a glycoprotein member of the glycosyl hydrolase 18 family. The protein lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. The protein is thought to play a role in the process of inflammation and tissue remodeling.

Gene names and symbols associated with CHI3L1

  • chitinase 3-like 1 (Chi3l1) antibody
  • chitinase 3-like 1 (cartilage glycoprotein-39) (CHI3L1) antibody
  • chitinase 3-like 1 (cartilage glycoprotein-39) (Chi3l1) antibody
  • ASRT7 antibody
  • AW208766 antibody
  • BP40 antibody
  • Brp39 antibody
  • CGP-39 antibody
  • Chil1 antibody
  • CLP-1 antibody
  • GP-39 antibody
  • GP38K antibody
  • GP39 antibody
  • HC-gp39 antibody
  • HCGP-3P antibody
  • hCGP-39 antibody
  • MGP-40 antibody
  • SPC-40 antibody
  • SPS-40 antibody
  • YKL-40 antibody
  • YKL40 antibody
  • YYL-40 antibody

Protein level used designations for CHI3L1

CGP-39 , GP-39 , cartilage glycoprotein 39 , chitinase-3-like protein 1 , 39 kDa synovial protein , 38 kDa heparin-binding glycoprotein , signal-processing protein , 39 kDa whey protein , 40 kDa secretory signalling glycoprotein , cartilage glycoprotein-39 , chitinase-like protein 1 , signal processing protein , chitinase 3-like 1 protein , mammary gland protein 40

GENE ID SPECIES
12654 Mus musculus
1116 Homo sapiens
396865 Sus scrofa
286869 Bos taurus
89824 Rattus norvegicus
100860825 Capra hircus
443279 Ovis aries
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