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Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. Additionally we are shipping Chitinase 3-Like 1 (Cartilage Glycoprotein-39) Kits (65) and Chitinase 3-Like 1 (Cartilage Glycoprotein-39) Proteins (17) and many more products for this protein.
Showing 10 out of 68 products:
Human Polyclonal CHI3L1 Primary Antibody for ELISA - ABIN1998531
Rehli, Niller, Ammon, Langmann, Schwarzfischer, Andreesen, Krause: Transcriptional regulation of CHI3L1, a marker gene for late stages of macrophage differentiation. in The Journal of biological chemistry 2003
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Human Monoclonal CHI3L1 Primary Antibody for EIA, IHC (p) - ABIN356240
Bonneh-Barkay, Bissel, Wang, Fish, Nicholl, Darko, Medina-Flores, Murphey-Corb, Rajakumar, Nyaundi, Mellors, Bowser, Wiley: YKL-40, a marker of simian immunodeficiency virus encephalitis, modulates the biological activity of basic fibroblast growth factor. in The American journal of pathology 2008
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Cow (Bovine) Polyclonal CHI3L1 Primary Antibody for IF, WB - ABIN2784693
Ober, Tan, Sun, Possick, Pan, Nicolae, Radford, Parry, Heinzmann, Deichmann, Lester, Gern, Lemanske, Nicolae, Elias, Chupp: Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function. in The New England journal of medicine 2008
IL-18 (show IL18 Antibodies) is a potent stimulator of Chi3l1 and that Chi3l1 is an important mediator of IL-18 (show IL18 Antibodies)-induced inflammatory, fibrotic, alveolar remodeling, and cytotoxic responses.
CHI3L1 is induced during fungal infection, and it regulated antifungal innate immune responses in the cornea.
Astrocytic expression of chitinase 3-like protein 1 limits the extent of both astrocytic and microglial/macrophage facets of neuroinflammation.
Results do not support a role of BRP (show GDF5 Antibodies)-39 in the pathogenesis of experimental autoimmune encephalitis.
CHI3L1 was increased in plasma and brain tissue in experimental cerebral malaria, but targeted Chi3l1 deletion did not alter cytokine production or survival in this model.
mechanism of BRP (show GDF5 Antibodies)-39 in bleomycin-induced pulmonary fibrosis
Sem7a and its receptors regulate Chi3l1 in pulmonary melanoma metastasis
Data show that IL-1 (show IL1A Antibodies)-induced transcriptin factor RelB (show RELB Antibodies)/NF-kappa B p50 (show NFKB1 Antibodies) Subunit complex formation was further promoted by oncostatin M (show OSM Antibodies) and that these complexes directly bound to the secreted protein cartilage glycoprotein 39 (YKL-40) promoter.
These results indicate that catalytically inactive BRP (show GDF5 Antibodies)-39 and Ym1 (show CHI3L3 Antibodies) are constitutive genes in normal mouse lung.
BRP (show GDF5 Antibodies)-39 is involved in repressing the M1 proinflammatory phenotype in hyperoxia, thereby deactivating inflammatory responses in macrophages and preventing neonatal lung injury.
Serum YKL-40 level increases with severity of obstructive sleep apnea syndrome (OSAS). The findings suggest that YKL-40 may be a useful biomarker for inflammation in patients with OSAS.
CHI3L1 is expressed during the process of differentiation and maturation of dendritic cells in time dependent manner, it could play a crucial role in the dendritic cells immune response.
Neurogranin (show NRGN Antibodies) and YKL-40 are promising AD biomarkers, independent of and complementary to the established core Alzheimer's disease (AD) biomarkers, reflecting additional pathological changes in the course of AD
Data show that the expression of chitinase 3-like 1 (cartilage glycoprotein-39) protein (CHI3L1) was higher in cancerous tissues than in normal tissues.
The serum YKL-40 cutoff to identify beta-thalassemia major patients with liver cirrhosis or heart disease was determined.
We identified five new biomarkers: GDF15 (show GDF15 Antibodies), osteonectin (show SPARC Antibodies), TRAP5, TWEAK (show TNFSF12 Antibodies), and YKL40 as being promising markers for monitoring bone metastases.
Pregnancy seems to be associated with a temporary reduction in circulating YKL-40, which increases after delivery, but to a much lesser extent in women with GDM than in non-GDM women.
cerebrospinal fluid CHI3L1 and CHI3L2 (show CHI3L2 Antibodies) and serum CHI3L1 might help to define multiple sclerosis disease stage
Serum YKL-40 together with serum CTX (show CYP27A1 Antibodies)-MMP/PINP ratio and World Health Organization status were independent predictors of time to first SRE.
We also demonstrated that miR (show MLXIP Antibodies)-24 suppressed the expression of chitinase 3-like 1 (CHI3L1) mRNA, thought to mediate multiple signaling pathways
chitinase-like lectin, YKL-40, binds specifically to type I collagen and modulates the rate of type I collagen fibril formation
Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 family of chitinases includes eight human family members. This gene encodes a glycoprotein member of the glycosyl hydrolase 18 family. The protein lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. The protein is thought to play a role in the process of inflammation and tissue remodeling.
, cartilage glycoprotein 39
, chitinase-3-like protein 1
, 39 kDa synovial protein
, 38 kDa heparin-binding glycoprotein
, signal-processing protein
, 39 kDa whey protein
, 40 kDa secretory signalling glycoprotein
, cartilage glycoprotein-39
, chitinase-like protein 1
, signal processing protein
, chitinase 3-like 1 protein
, mammary gland protein 40