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Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. Additionally we are shipping Chitinase 3-Like 1 (Cartilage Glycoprotein-39) Kits (51) and Chitinase 3-Like 1 (Cartilage Glycoprotein-39) Proteins (19) and many more products for this protein.
Showing 10 out of 66 products:
Human Polyclonal CHI3L1 Primary Antibody for ELISA - ABIN1998531
Rehli, Niller, Ammon, Langmann, Schwarzfischer, Andreesen, Krause: Transcriptional regulation of CHI3L1, a marker gene for late stages of macrophage differentiation. in The Journal of biological chemistry 2003
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Human Monoclonal CHI3L1 Primary Antibody for EIA, IHC (p) - ABIN356240
Bonneh-Barkay, Bissel, Wang, Fish, Nicholl, Darko, Medina-Flores, Murphey-Corb, Rajakumar, Nyaundi, Mellors, Bowser, Wiley: YKL-40, a marker of simian immunodeficiency virus encephalitis, modulates the biological activity of basic fibroblast growth factor. in The American journal of pathology 2008
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Cow (Bovine) Polyclonal CHI3L1 Primary Antibody for IF, WB - ABIN2784693
Ober, Tan, Sun, Possick, Pan, Nicolae, Radford, Parry, Heinzmann, Deichmann, Lester, Gern, Lemanske, Nicolae, Elias, Chupp: Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function. in The New England journal of medicine 2008
CHI3L1-mediated cell proliferation/survival involves partial downregulation of the pro-apoptotic S100A9 (show S100A9 Antibodies) protein that is highly expressed during the acute phase of colitis, by binding to the S100A9 (show S100A9 Antibodies) receptor, RAGE (show AGER Antibodies) (Receptor for Advanced Glycation End products).
IL-18 (show IL18 Antibodies) is a potent stimulator of Chi3l1 and that Chi3l1 is an important mediator of IL-18 (show IL18 Antibodies)-induced inflammatory, fibrotic, alveolar remodeling, and cytotoxic responses.
CHI3L1 is induced during fungal infection, and it regulated antifungal innate immune responses in the cornea.
Astrocytic expression of chitinase 3-like protein 1 limits the extent of both astrocytic and microglial/macrophage facets of neuroinflammation.
Results do not support a role of BRP (show GDF5 Antibodies)-39 in the pathogenesis of experimental autoimmune encephalitis.
CHI3L1 was increased in plasma and brain tissue in experimental cerebral malaria, but targeted Chi3l1 deletion did not alter cytokine production or survival in this model.
mechanism of BRP (show GDF5 Antibodies)-39 in bleomycin-induced pulmonary fibrosis
Sem7a and its receptors regulate Chi3l1 in pulmonary melanoma metastasis
Data show that IL-1 (show IL1A Antibodies)-induced transcriptin factor RelB (show RELB Antibodies)/NF-kappa B p50 (show NFKB1 Antibodies) Subunit complex formation was further promoted by oncostatin M (show OSM Antibodies) and that these complexes directly bound to the secreted protein cartilage glycoprotein 39 (YKL-40) promoter.
These results indicate that catalytically inactive BRP (show GDF5 Antibodies)-39 and Ym1 (show CHI3L3 Antibodies) are constitutive genes in normal mouse lung.
Time-dependent increase of chitinase1 in APP (show APP Antibodies)/PS1 (show PSEN1 Antibodies) double transgenic mice indicates that the level of chitinase1 is associated with decline of cognition.
Glycoprotein YKL-40 could be considered a biomarker of chronic graft-vs-host disease severity and activity
High expression of YKL40 is associated with cholangiocarcinoma.
Polymorphism in the CHI3L1 rs4950928 C allele is associated with rectal cancer.
Unexpectedly and contrary to some other findings in cancer tissues, this study has shown a correlation between high YKL-40 tumor cell/matrix ratio and longer overall survival in human osteosarcoma.
Data show that calcitriol and lysophosphatidic acid converge to enhance chitinase-3-like protein 1 (YKL-40) production by osteosarcoma-derived osteoblast, MG63.
Serum YKL-40 level seems to be unuseful for monitoring the effect of treatment in knee osteoarthritis.
Gingival crevicular fluid YKL-40 level was elevated in periodontitis, but not diabetes mellitus . YKL-40 in GCF (show GUCY2F Antibodies) may be an inflammatory marker for periodontitis.
Serum YKL-40 levels are elevated in patients with gestational diabetes mellitus but are unaffected by the oral glucose tolerance test. YKL-40 levels are related to glycated hemoglobin (show HBB Antibodies), fasting insulin (show INS Antibodies) and HOMA-IR. These results suggest that YKL-40 may be a major contributor to gestational diabetes mellitus.
chitinase-like lectin, YKL-40, binds specifically to type I collagen and modulates the rate of type I collagen fibril formation
Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 family of chitinases includes eight human family members. This gene encodes a glycoprotein member of the glycosyl hydrolase 18 family. The protein lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. The protein is thought to play a role in the process of inflammation and tissue remodeling.
, cartilage glycoprotein 39
, chitinase-3-like protein 1
, 39 kDa synovial protein
, 38 kDa heparin-binding glycoprotein
, signal-processing protein
, 39 kDa whey protein
, 40 kDa secretory signalling glycoprotein
, cartilage glycoprotein-39
, chitinase-like protein 1
, signal processing protein
, chitinase 3-like 1 protein
, mammary gland protein 40