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anti-Claudin 14 (CLDN14) Antibodies

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. Additionally we are shipping CLDN14 Kits (27) and CLDN14 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CLDN14 23562 O95500
CLDN14 56173 Q9Z0S3
CLDN14 304073  
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Top anti-CLDN14 Antibodies at antibodies-online.com

Showing 10 out of 79 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA, WB ABIN184791 (1µg/ml) staining of human liver lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Cow Goat Un-conjugated EIA, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated WB CLDN14 Antibody (C-term) (ABIN1881208) western blot analysis in MDA-MB453 cell line lysates (35 µg/lane). This demonstrates the CLDN14 antibody detected the CLDN14 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: Hela B: Hep G2 , 12% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Goat Un-conjugated IHC (p), IHC, ELISA, WB ABIN249595 (1µg/ml) staining of Human Liver lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 5 to 7 Days
$427.88
Details
Human Goat Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Goat Un-conjugated IHC, ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Goat Un-conjugated IHC (p), ELISA, WB Human Pancreas (formalin-fixed, paraffin-embedded) stained with CLDN14 antibody ABIN337255 at 5 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated ICC, IF, WB   50 μg Log in to see 8 to 10 Days
$595.83
Details
Human Rabbit Un-conjugated IHC (p), WB   50 μL Log in to see 8 to 10 Days
$451.00
Details

CLDN14 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-CLDN14 Antibodies

  1. Human Polyclonal CLDN14 Primary Antibody for WB - ABIN1881208 : Thorleifsson, Holm, Edvardsson, Walters, Styrkarsdottir, Gudbjartsson, Sulem, Halldorsson, de Vegt, dAncona, den Heijer, Franzson, Christiansen, Alexandersen, Rafnar, Kristjansson: Sequence variants in the CLDN14 gene associate with kidney stones and bone mineral density. in Nature genetics 2009 (PubMed)
    Show all 3 references for ABIN1881208

  2. Human Polyclonal CLDN14 Primary Antibody for ELISA, WB - ABIN184791 : Wilcox, Burton, Naz, Riazuddin, Smith, Ploplis, Belyantseva, Ben-Yosef, Liburd, Morell, Kachar, Wu, Griffith, Riazuddin, Friedman: Mutations in the gene encoding tight junction claudin-14 cause autosomal recessive deafness DFNB29. in Cell 2001 (PubMed)

More Antibodies against CLDN14 Interaction Partners

Human Claudin 14 (CLDN14) interaction partners

  1. Rs1801725 (Ala986-Ser (show SIGLEC1 Antibodies)), rs1042636 (Arg990Gly) of CaSR (show CASR Antibodies) gene and rs219778, rs219780 (Thr229Thr) of CLDN14 gene were significantly associated with kidney stone disease in patients from the Eastern part of India.

  2. Claudin 14 expression was up-regulated in gastric cancer.

  3. CLDN14 mutations can contribute to the aetiology of childhood/congenital deafness in Moroccan patients.

  4. Human Cldn-8 (show CLDN8 Antibodies) and -14 were shown to convey Clostridium perfringens enterotoxin-mediated cytotoxicity at pathophysiologically relevant concentrations of this toxin, although ~2-to-10-fold less efficiently than Cldn-4 (show CLDN4 Antibodies).

  5. OPRM1 (show OPRM1 Antibodies) genetic polymorphisms are associated with the plasma concentration of cotinine in a Taiwanese MMT cohort. Carriers with the major allele of SNP rs1799971 had a higher plasma cotinine concentration.

  6. The hearing loss due to novel CLDN14 mutations is prelingual, severe-to-profound with greater loss in the high frequencies.

  7. The CLDN14 promoter is activated by Trichostatin A (TSA (show PRDX2 Antibodies)) treatment according to promoter reporter assays in HEK (show EPHA3 Antibodies) 293 cells.

  8. Individuals with mutations of CLDN14 may have different degrees of hearing loss and the loss is greater at higher frequencies.

  9. The palmitoylation of claudin-14 is required for efficient localization into tight junctions but not stability or strand assembly.

  10. The ability of CLDN14 to be recruited to these junctions is crucial for the hearing process.

Mouse (Murine) Claudin 14 (CLDN14) interaction partners

  1. claudin-14-targeting miR (show MLXIP Antibodies)-9 and miR (show MLXIP Antibodies)-374, rather than promoter of the claudin-14 gene itself, regulated through histone deacetylation

  2. describe a CaSR (show CASR Antibodies)-NFATc1 (show NFATC1 Antibodies)-microRNA-claudin-14 signaling pathway in the kidney that underlies paracellular Ca(++) reabsorption through the tight junction

  3. Activation of the Ca(2 (show CA2 Antibodies)+)-sensing receptor in the thick ascending limb increases Cldn14 expression, which in turn blocks the paracellular reabsorption of Ca(2 (show CA2 Antibodies)+).

  4. MiR (show MLXIP Antibodies)-9 and miR (show MLXIP Antibodies)-374 transcript levels are regulated by extracellular Ca(++) in a reciprocal manner as claudin-14.

  5. To explore the role of claudin 14 in the inner ear and in other tissues we created a mouse model by a targeted deletion of Cldn14.

  6. We generated claudin 11 (show CLDN11 Antibodies)/claudin 14 double-deficient mice, which exhibit deafness, neurological deficits, and male sterility. Kidney function and ion balance are not significantly affected.

CLDN14 Antigen Profile

Protein Summary

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. The encoded protein also binds specifically to the WW domain of Yes-associated protein. Defects in this gene are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness. It is also reported that four synonymous variants in this gene are associated with kidney stones and reduced bone mineral density. Several transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with anti-Claudin 14 (CLDN14) Antibodies

  • claudin 14 (cldn14) antibody
  • claudin 14 (CLDN14) antibody
  • claudin 14 (Cldn14) antibody
  • claudin 14 (LOC100346496) antibody
  • AI851731 antibody
  • claudin-14 antibody
  • CLDN14 antibody
  • DFNB29 antibody

Protein level used designations for anti-Claudin 14 (CLDN14) Antibodies

claudin 14 , claudin-14

GENE ID SPECIES
444474 Xenopus laevis
470085 Pan troglodytes
783180 Bos taurus
23562 Homo sapiens
56173 Mus musculus
304073 Rattus norvegicus
487751 Canis lupus familiaris
100302017 Sus scrofa
100726532 Cavia porcellus
427982 Gallus gallus
100346496 Oryctolagus cuniculus
101109068 Ovis aries
Selected quality suppliers for anti-CLDN14 (CLDN14) Antibodies
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