CLDN14 Products
(Claudin 14 (CLDN14))
Categories
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. The encoded protein also binds specifically to the WW domain of Yes-associated protein. Defects in this gene are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness. It is also reported that four synonymous variants in this gene are associated with kidney stones and reduced bone mineral density. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2010].
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Featured CLDN14 Categories
CLDN14 Antibodies
High quality antibodies with extensive validation data.
CLDN14 ELISA Kits
Reliable ELISA kits for a wide range of species.
CLDN14 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CLDN14 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7147891
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (3)
- (2)
Cat. No.
ABIN1881208
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN184791
Quantity
100 μg
Datasheet
Datasheet
Recommended CLDN14 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN1742853
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Sheep
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN1773757
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN1745293
Quantity
96 tests
Datasheet
Datasheet
Recommended CLDN14 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1349591
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1349593
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3111275
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our CLDN14 products
: "Activation of the Ca(2+)-sensing receptor increases renal claudin-14 expression and urinary Ca(2+) excretion." in: American journal of physiology. Renal physiology, Vol. 304, Issue 6, pp. F761-9, (2013) (PubMed).: "Identification of transcription factor E3 (TFE3) as a receptor-independent activator of Gα16: gene regulation by nuclear Gα subunit and its activator." in: The Journal of biological chemistry, Vol. 286, Issue 20, pp. 17766-76, (2011) (PubMed).
: "Sequence variants in the CLDN14 gene associate with kidney stones and bone mineral density." in: Nature genetics, Vol. 41, Issue 8, pp. 926-30, (2009) (PubMed).
: "Mutation in gap and tight junctions in patients with non-syndromic hearing loss." in: Biochemical and biophysical research communications, Vol. 385, Issue 1, pp. 1-5, (2009) (PubMed).
: "Mutations in the gene encoding tight junction claudin-14 cause autosomal recessive deafness DFNB29." in: Cell, Vol. 104, Issue 1, pp. 165-72, (2001) (PubMed).
: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." in: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, (1996) (PubMed).
Synonyms and alternative names related to CLDN14
claudin 14 L homeolog (cldn14.L), claudin 14 (CLDN14), claudin 14 (Cldn14), AI851731, claudin-14, CLDN14, DFNB29Protein level used designations for CLDN14
- claudin 14
- claudin-14
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