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anti-Collagen, Type XVIII, alpha 1 (COL18A1) Antibodies

COL18A1 encodes the alpha chain of type XVIII collagen. Additionally we are shipping COL18A1 Kits (57) and COL18A1 Proteins (21) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
COL18A1 80781 P39060
COL18A1 12822 P39061
COL18A1 85251  
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Top anti-COL18A1 Antibodies at

Showing 10 out of 166 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated IHC (fro), IHC (p)   0.2 mg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human kidney carcinoma labeled with Anti-Endostatin Polyclonal Antibody (ABIN669951), Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin fixed and paraffin embedded human hepatocarcinoma stained with COL18A1 Antibody (Center) Cat.-No AP51011PU-N  followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the COL18A1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. Western blot analysis in mouse liver tissue lysates (35ug/lane) using COL18A1 Antibody (Center) Cat.-No AP51011PU-N.This demonstrates the COL18A1 antibody detected the COL18A1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
Human Mouse Un-conjugated EIA, IHC (fro), FACS, IHC (p), WB   0.1 mg Log in to see 6 to 8 Days
Human Mouse Un-conjugated IHC (p), WB Immunohistochemistry-Paraffin: Endostatin Antibody (1873.46) [NBP1-40051] - Analysis of anti-COL18A1 / Endostatin antibody with human kidney at dilution 1:100. 0.05 mL Log in to see 5 to 7 Days
Human Rabbit Un-conjugated IHC (p), WB COL18A1 Antibody (Center) (ABIN654663) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
Chicken Rat Un-conjugated ELISA, WB   0.1 mg Log in to see 5 to 7 Days
Human Rabbit Un-conjugated IF, IHC (p), ELISA Human Breast, Collagen: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 8 to 10 Days
Human Mouse Un-conjugated IHC (p), WB 50 μL Log in to see 6 to 8 Days
Human Rabbit Un-conjugated WB 100 μg Log in to see 2 to 3 Days

COL18A1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-COL18A1 Antibodies

  1. Human Polyclonal COL18A1 Primary Antibody for IF (p), IHC (p) - ABIN669951 : Gao, Zhao, Liang, Li, Cao, Liu: Effect of peritoneal dialysis on expression of vascular endothelial growth factor, basic fibroblast growth factor and endostatin of the peritoneum in peritoneal dialysis patients. in Nephrology (Carlton, Vic.) 2011 (PubMed)
    Show all 3 references for ABIN669951

  2. Human Monoclonal COL18A1 Primary Antibody for IHC (p), WB - ABIN448134 : Chen, Hsu, Song, Huang, Tsai, Kuo, Hsu, Tsai, Tsai, Woung, Chiou, Lu, Chen: Celecoxib enhances radiosensitivity in medulloblastoma-derived CD133-positive cells. in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2010 (PubMed)
    Show all 2 references for ABIN448134

  3. Chicken Monoclonal COL18A1 Primary Antibody for ELISA, WB - ABIN265797 : Jung, Lim: The antiangiogenic and antinociceptive activities of n-propyl gallate. in Phytotherapy research : PTR 2011 (PubMed)

More Antibodies against COL18A1 Interaction Partners

Pig (Porcine) Collagen, Type XVIII, alpha 1 (COL18A1) interaction partners

  1. Investigate the timecourse of collagen XVIII processing with release of endostatin (ES) and other low-molecular-weight fragments during early ischemia-reperfusion of the heart.

Zebrafish Collagen, Type XVIII, alpha 1 (COL18A1) interaction partners

  1. Together these data suggest that Lh3 (show PLOD3 Antibodies)-Collagen18A1 dependent ECM (show MMRN1 Antibodies) modifications regulate the transition of trunk neural crest cells from a non-segmental sheet like migration mode to a segmental stream migration mode

  2. These results provide important insight into the biological function and regulation of COL18A1, and point to additional sequences that may contribute to complex diseases involving COL18A1.

  3. diwanka (lh3 (show PLOD3 Antibodies)) acts through myotomal type XVIII collagen, a ligand for neural-receptor protein tyrosine phosphatases that guide motor axons

Human Collagen, Type XVIII, alpha 1 (COL18A1) interaction partners

  1. The homozygous DN and NN genotypes of COL18A1 D104N were associated with the risk of osteosarcoma.

  2. Endostatin is increased in patients with primary sjogren's syndrome patients with interstitial lung disease.

  3. Data show that endostatin levels were elevated in patients with systemic sclerosis (SSc (show CYP11A1 Antibodies)) and mixed connective tissue disease (MCTD).

  4. Collaterals formation seems to be associated with the activation of pro-inflammatory factors, growth factors and endostatin in chronic heart failure.

  5. Genebased analyses revealed associations of the COL18A1 gene with longitudinal Blood Pressure phenotypes, associations with essential hypertension, Blood Pressure salt sensitivity, preeclampsia, or preclinical stages of atherosclerosis.

  6. Study demonstrates that endostatin has novel ATPase (show DNAH8 Antibodies) activity, which mediates its antiangiogenic and antitumor activities.

  7. ADAM8 (show ADAM8 Antibodies) and endostatin play a role in osteosarcoma progression.

  8. the intima+media of IPAH vessels, collagens (COL4A5 (show COL4a5 Antibodies), COL14A1 (show COL14A1 Antibodies), and COL18A1), matrix metalloproteinase (show MMP20 Antibodies) (MMP) 19 (show MMP19 Antibodies), and a disintegrin and metalloprotease (show ADAM8 Antibodies) (ADAM) 33 (show ADAM33 Antibodies) were higher expressed, whereas MMP10 (show MMP10 Antibodies), ADAM17 (show ADAM17 Antibodies), TIMP1 (show TIMP1 Antibodies), and TIMP3 (show TIMP3 Antibodies) were less abundant.

  9. High endostatin expression is associated with malignant pleural effusions in lung cancer.

  10. In 2 large cohort studies using serum endostatin as a marker for disease severity and mortality in pulmonary arterial hypertension, a variant in the gene encoding ES, Col18a1, was linked independently with reduced mortality.

Mouse (Murine) Collagen, Type XVIII, alpha 1 (COL18A1) interaction partners

  1. There are correlations between the elevation of endostatin levels and parallel microvascular rarefaction and induction of renal fibrosis in aging mice.

  2. An excess of the collagen XVIII Tsp-1 (show GZMA Antibodies) domain is deleterious in the eye, possibly by impairing certain functions of the full-length molecule.

  3. The results of the present study indicate endostatin promotes soft callus formation but inhibits callus remodeling during fracture healing most probably by an inhibition of angiogenesis.

  4. Data indicate that delivery by attenuated Salmonella of the combination therapeutic plasmid simultaneously knocked down the expression of Stat3 (show STAT3 Antibodies) and resulted in over-expression of Endostatin, which synergistically inhibited prostate cancer growth.

  5. Endostatin lowers blood pressure via nitric oxide and prevents hypertension associated with VEGF inhibition

  6. Women with early-onset, but not late-onset preeclampsia have higher levels of endostatin than healthy pregnant women in corresponding lengths of gestation.

  7. In vivo, Collagen XVIII/endostatin does not play an indispensable role in skeletal development

  8. Lack of collagen XVIII/endostatin results in eye abnormalities.

  9. Endostatin gene transfer inhibits joint angiogenesis and pannus formation in inflammatory arthritis

  10. Endostatin expression effectively inhibits mammary neoplasms growth in nude mice

COL18A1 Antigen Profile

Protein Summary

This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. The proteolytically produced C-terminal fragment of type XVIII collagen is endostatin, a potent antiangiogenic protein. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with COL18A1

  • collagen, type XVIII, alpha 1 (COL18A1) antibody
  • collagen, type XVIII, alpha 1 (col18a1) antibody
  • collagen type XVIII, alpha 1 (col18a1) antibody
  • collagen, type XVIII, alpha 1 (Col18a1) antibody
  • cb371 antibody
  • cb529 antibody
  • fc96d06 antibody
  • KNO antibody
  • KNO1 antibody
  • KS antibody
  • sb:cb529 antibody
  • wu:fb47h10 antibody
  • wu:fb77g12 antibody
  • wu:fc50f04 antibody
  • wu:fc96d06 antibody
  • wu:fk02h12 antibody

Protein level used designations for COL18A1

collagen, type XVIII, alpha 1 , alpha 1 type XVIII collagen , collagen alpha-1(XVIII) chain , procollagen, type XVIII, alpha 1 , collagen alpha-1(XVIII) chain-like , endostatin , antiangiogenic agent , multi-functional protein MFP

373978 Gallus gallus
394845 Xenopus (Silurana) tropicalis
474050 Pan troglodytes
508076 Bos taurus
100464575 Ailuropoda melanoleuca
100579175 Sus scrofa
564123 Danio rerio
80781 Homo sapiens
12822 Mus musculus
100126771 Canis lupus familiaris
85251 Rattus norvegicus
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