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anti-Contactin Associated Protein 1 (CNTNAP1) Antibodies

The gene product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. Additionally we are shipping CNTNAP1 Kits (19) and CNTNAP1 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CNTNAP1 8506 P78357
CNTNAP1 84008 P97846
CNTNAP1 53321 O54991
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Top anti-CNTNAP1 Antibodies at antibodies-online.com

Showing 10 out of 41 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Mouse Un-conjugated IF, IP, IHC, WB Western blot analysis of p190 on HeLa lysate. Lane 1: 1:500, lane 2: 1:1000, lane 3: 1:2000 dilution of p190. Human Fibroblast 50 μg Log in to see 5 to 6 Days
$205.42
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000;  TMB staining;  Read the data in MicroplateReader by 450 U251 cells (human glioma cells) were probed with Rabbit Anti-CASPR/Neurexin4 Polyclonal Antibody, Unconjugatedused at 1:200 dilution for 40 minutes at 37°C 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Mouse Un-conjugated ICC, IF, IP, WB   100 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$365.20
Details
Human Mouse Un-conjugated IF, WB   100 μg Log in to see 8 to 10 Days
$625.17
Details
Human Rabbit Biotin IHC (p), WB   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

CNTNAP1 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-CNTNAP1 Antibodies

  1. Chicken Monoclonal CNTNAP1 Primary Antibody for IF, IP - ABIN967780 : Brandt, Gimona, Hillmann, Haller, Mischak: Protein kinase C induces actin reorganization via a Src- and Rho-dependent pathway. in The Journal of biological chemistry 2002 (PubMed)
    Show all 5 references for ABIN967780

  2. Human Polyclonal CNTNAP1 Primary Antibody for WB - ABIN2782237 : Nie, Zhou, Ang, Teng, Xu, Xiang, Wang, Zeng, Takeda, Xu, Ng, Faivre-Sarrailh, Popko, Ling, Schachner, Watanabe, Pallen, Tang, Xiao: Nogo-A at CNS paranodes is a ligand of Caspr: possible regulation of K(+) channel localization. in The EMBO journal 2003 (PubMed)

More Antibodies against CNTNAP1 Interaction Partners

Human Contactin Associated Protein 1 (CNTNAP1) interaction partners

  1. Mutations in CNTNAP1 and ADCY6 (show ADCY6 Antibodies) are responsible for severe arthrogryposis multiplex congenita with axoglial defects

  2. VDAC1 (show VDAC1 Antibodies) and CNTNAP1 associate with gamma-secretase in detergent-resistant membranes and affect amyloid precursor protein (show APP Antibodies) processing.

Mouse (Murine) Contactin Associated Protein 1 (CNTNAP1) interaction partners

  1. Simultaneous deletion of Caspr and Caspr2 (show CNTNAP2 Antibodies) disrupts the internodal organization of Kv1.2 (show KCNA2 Antibodies).

  2. Caspr co-localizes and interacts with APP (show APP Antibodies). Amyloid-beta (Abeta (show APP Antibodies)) 40 and Abeta42 generation were also reduced in HEK (show EPHA3 Antibodies)-APP (show APP Antibodies) cells by Caspr overexpression.

  3. Caspr labeling was observed through much of the retina, including horizontal, bipolar, amacrine, and ganglion cells.

  4. Clustering of Caspr at initial contact sites between OL processes and the axon requires glial expression of NF155 but not of contactin. Expression of membrane proteins along the axolemma is determined by the type of the contacting glial cells.

  5. These results suggest that Caspr serves as a "transmembrane scaffold" that stabilizes the Caspr/contactin adhesion complex at the paranodal junction by connecting it to cytoskeletal components within the axon.

  6. F3/contactin and caspr/paranodin traffic to the cell surface via a non-conventional pathway

  7. Nogo-A (show RTN4 Antibodies) interacts in trans with axonal Caspr at CNS paranodes, an interaction that may have a role in modulating axon-glial junction architecture and possibly K(+)-channel (show KCNC4 Antibodies) localization during development.

  8. the Caspr/Cont complex is essential for the formation of axoglial SJ

  9. Caspr protein is required for recruitment and retention of KCNQ4 (show KCNQ4 Antibodies) at calyceal synapses in vestibular hair cells.

  10. The Caspr gene has been identified in the neurological mutant shambling (shm) mouse and shown to encode the contactin-associated protein, which is a major component of the paranodal junction in myelinated nerves.

CNTNAP1 Antigen Profile

Protein Summary

The gene product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,384-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein,' includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. Northern blot analysis showed that the gene is transcribed predominantly in brain as a transcript of 6.2 kb, with weak expression in several other tissues tested. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons.

Gene names and symbols associated with CNTNAP1

  • contactin associated protein 1 (CNTNAP1) antibody
  • contactin associated protein 1 (cntnap1) antibody
  • contactin associated protein 1 (Cntnap1) antibody
  • contactin associated protein 1 (LOC100351604) antibody
  • contactin associated protein-like 1 (Cntnap1) antibody
  • AI841080 antibody
  • Caspr antibody
  • CNTNAP antibody
  • CNTNAP1 antibody
  • NCP1 antibody
  • Nrxn4 antibody
  • p190 antibody
  • shm antibody

Protein level used designations for CNTNAP1

contactin associated protein 1 , contactin-associated protein 1-like , caspr1 , contactin-associated protein 1 , neurexin 4 , neurexin IV , neurexin-4 , p190 , paranodin , MHDNIV , neurexin 4 (contactin associated protein)

GENE ID SPECIES
454696 Pan troglodytes
100037844 Xenopus (Silurana) tropicalis
100390860 Callithrix jacchus
100450795 Pongo abelii
100481010 Ailuropoda melanoleuca
100559472 Anolis carolinensis
100604186 Nomascus leucogenys
8506 Homo sapiens
84008 Rattus norvegicus
100351604 Oryctolagus cuniculus
100719034 Cavia porcellus
100521039 Sus scrofa
490960 Canis lupus familiaris
540997 Bos taurus
428309 Gallus gallus
101111565 Ovis aries
53321 Mus musculus
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