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Cytochrome P450, Family 27, Subfamily B, Polypeptide 1 (CYP27B1) ELISA Kits

CYP27B1 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP27B1 Antibodies (25) and CYP27B1 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CYP27B1 1594 O15528
CYP27B1 114700 O35132
CYP27B1 13115 O35084
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Top CYP27B1 ELISA Kits at antibodies-online.com

Showing 3 out of 9 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 7.81 pg/mL 31.25-2000 pg/mL   96 Tests Log in to see 11 to 13 Days
$910.56
Details
Mouse 0.235 ng/mL 0.62-40 ng/mL 96 Tests Log in to see 9 to 11 Days
$757.89
Details
Rat 0.625-40 ng/mL   96 Tests Log in to see 11 to 13 Days
$1,029.60
Details

Top referenced CYP27B1 ELISA Kits

  1. Human CYP27B1 ELISA Kit for Sandwich ELISA - ABIN857741 : Braithwaite, Choonara, Kumar, Tomar, Du Toit, Pillay: A novel bile salts-lipase polymeric film-infused minitablet system for enhanced oral delivery of cholecalciferol. in Pharmaceutical development and technology 2015 (PubMed)

More ELISA Kits for CYP27B1 Interaction Partners

Cow (Bovine) Cytochrome P450, Family 27, Subfamily B, Polypeptide 1 (CYP27B1) interaction partners

  1. Data show that in tissue and secreted cells from the infected mammary glands, 25-hydroxyvitamin D(3) 1alpha-hydroxylase (1alpha-OHase; CYP27B1) gene expression was significantly increased compared to expression in tissue and cells from the healthy mammary tissue.

Human Cytochrome P450, Family 27, Subfamily B, Polypeptide 1 (CYP27B1) interaction partners

  1. This study reveals no association between CYP27B1 polymorphisms and blood levels of 1alpha,25-hydroxyvitamin D.

  2. this study indicates rs8176345 in CYP27B1 gene is significantly correlated with erlotinib-induced skin rash in patients with advanced non-small cell lung cancer

  3. Vitamin D-binding protein (show GC ELISA Kits) SNPs are associated with prostate cancer; low 25(OH)D metabolism score and CYP24A1 (show CYP24A1 ELISA Kits) and CYP27B1 variants are associated with grade

  4. Increased CYP27B1 expression and local duodenal 1,25(OH)2D3 production during puberty may be a metabolic adaptation that promotes dietary calcium absorption.

  5. Data show that cytochrome P450 (show CYP ELISA Kits) CYP27B1 and CYP24A1 (show CYP24A1 ELISA Kits) expression were significantly different between tumor and normal tissues in non-small cell lung cancer (NSCLC).

  6. Data suggest compound heterozygous mutations in CYP27B1 (missense/frameshift mutations) in 2 brothers are associated with vitamin D-dependent rickets type 1A; entering puberty urinary calcium is marker for secondary hyperparathyroidism. [CASE REPORT]

  7. The CYP27B1+2838 polymorphism may be useful as pretreatment factor to selection of patients with higher probability of response to therapy.

  8. LNCaP cells were stably transfected with CYP27B.

  9. Results suggest that local expression of CYP27B1 in ovarian tumor cells can modify their behavior and promote a less aggressive phenotype by affecting local concentrations of active of vitamin D levels within the tumor microenvironment.

  10. Case Report: novel pathogenic missense mutation (CYP27B1:Homozygous c.1510C > T(p.Q504X)) causing vitamin D-dependent rickets type 1.

Mouse (Murine) Cytochrome P450, Family 27, Subfamily B, Polypeptide 1 (CYP27B1) interaction partners

  1. P450C1 alpha deficiency results in abnormal calcium handling and cardiac dysfunction in mice with defective vitamin D signaling.

  2. Throughout the male reproductive tract specific bands of CYP27B1 are determined.

  3. observed a 3- to 10-fold increase in CYP27B1 mRNA abundance in the lung, spleen, aorta and testis of FGF-23 (show FGF23 ELISA Kits) null/1alpha-Luc mice

  4. Data show that the absence of either of the two key hydroxylases, vitamin D 25-hydroxylase (CYP2R1 (show CYP2R1 ELISA Kits)) or vitamin D 25-hydroxyvitamin D-1alpha-hydroxylase (CYP27B1)neither inhibits nor enhances the development of experimental autoimmune encephalomyelitis (EAE).

  5. These results confirm the expression of vitamin D receptor (show VDR ELISA Kits) and Cyp27b1 in vivo and suggest a potential role for vitamin D(3) in skeletal muscle regeneration following injury.

  6. Bone formation parameters were increased significantly in all pups fed by dams on the rescue diet but were still lower in 1alpha(OH)ase(-/-) pups than in 1alpha(OH)ase(+/-) pups.

  7. regulation of bone CYP27B1 is unique from that in the kidney, and may play an important role in bone formation

  8. study shows CYP27B1 can hydroxylate 25-hydroxyvitamin D2 & 25-hydroxyvitamin D3 associated with phospholipid membranes; low activity found at higher membrane levels of 25-hydroxyvitamin D; substrate inhibition may contribute to enzyme activity regulation

  9. findings demonstrate that regulation of both the 25-hydroxyvitamin D-1 alpha-hydroxylase and 25-hydroxyvitamin D-24-hydroxylase (show CYP24A1 ELISA Kits) genes by phosphorus is disordered in hypophosphatemic mice at the level of renal mRNA expression

  10. both 1alphaOHase gene ablation and Pi supplementation inhibit renal calcification in Npt2 (show SLC34A1 ELISA Kits)-/- mice and that 1,25(OH)2D is essential for the development of hypercalciuria and nephrocalcinosis in the mutant strain.

CYP27B1 Antigen Profile

Antigen Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the inner mitochondrial membrane where it hydroxylates 25-hydroxyvitamin D3 at the 1alpha position. This reaction synthesizes 1alpha,25-dihydroxyvitamin D3, the active form of vitamin D3, which binds to the vitamin D receptor and regulates calcium metabolism. Thus this enzyme regulates the level of biologically active vitamin D and plays an important role in calcium homeostasis. Mutations in this gene can result in vitamin D-dependent rickets type I.

Gene names and symbols associated with CYP27B1

  • cytochrome P450, family 27, subfamily B, polypeptide 1 (cyp27b1) antibody
  • cytochrome P450, family 27, subfamily B, polypeptide 1 (CYP27B1) antibody
  • cytochrome P450, family 27, subfamily b, polypeptide 1 (Cyp27b1) antibody
  • Cp2b antibody
  • Cyp1 antibody
  • CYP1alpha antibody
  • Cyp27b antibody
  • Cyp40 antibody
  • P450c1 antibody
  • Pddr antibody
  • Vdd1 antibody
  • Vddr antibody
  • VddrI antibody
  • Vdr antibody

Protein level used designations for CYP27B1

cytochrome P450, family 27, subfamily B, polypeptide 1 , 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial , mitochondrial 25 hydroxyvitamin D3-1alpha-hydroxylase , 1alpha(OH)ase , 25 hydroxyvitamin D3-1-alpha hydroxylase , 25-OHD-1 alpha-hydroxylase , VD3 1A hydroxylase , calcidiol 1-monooxygenase , cytochrome P450 subfamily XXVIIB polypeptide 1 , cytochrome P450C1 alpha , cytochrome P450VD1-alpha , cytochrome p450 27B1 , 25-hydroxyvitamin D(3) 1-alpha-hydroxylase , P450C1 alpha , P450VD1-alpha , cytochrome P450 40 (25-hydroxyvitamin D3 1 alpha-hydroxylase) , cytochrome P450 subfamily XXVIIB (25-hydroxyvitamin D-1-alpha-hydroxylase) polypeptide 1 , cytochrome P450, 40 (25-hydroxyvitamin D3 1 alpha-hydroxylase) , cytochrome P450, subfamily 27b, polypeptide 1 , 25(OH)D 1alpha-hydroxylase , 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial precursor (25-OHD-1 alpha-hydroxylase) (25-hydroxyvitamin D3 1-alpha-hydroxylase) (VD3 1A hydroxylase) (P450C1 alpha) (P450VD1-alpha) , 25-hydroxyvitamin D3 1alpha-hydroxylase , P450VD1alpha , cytochrome P450, 27b1

GENE ID SPECIES
448754 Xenopus (Silurana) tropicalis
452027 Pan troglodytes
539630 Bos taurus
715747 Macaca mulatta
100034100 Equus caballus
1594 Homo sapiens
114700 Rattus norvegicus
13115 Mus musculus
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