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DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. Additionally we are shipping DDX3X Kits (12) and DDX3X Proteins (5) and many more products for this protein.
Showing 10 out of 139 products:
Human Polyclonal DDX3X Primary Antibody for EIA, IHC (p) - ABIN357007
Ariumi, Kuroki, Abe, Dansako, Ikeda, Wakita, Kato: DDX3 DEAD-box RNA helicase is required for hepatitis C virus RNA replication. in Journal of virology 2007
Show all 4 references for ABIN357007
Human Polyclonal DDX3X Primary Antibody for IHC (p), WB - ABIN388291
Liang, Yang, Li, Miao, Yang, Zou, Yuan: The Clinical and Pathological Significance of Nectin-2 and DDX3 Expression in Pancreatic Ductal Adenocarcinomas. in Disease markers 2015
Show all 2 references for ABIN388291
Dog (Canine) Polyclonal DDX3X Primary Antibody for IHC, WB - ABIN2775180
Shih, Tsai, Chao, Wu Lee: Candidate tumor suppressor DDX3 RNA helicase specifically represses cap-dependent translation by acting as an eIF4E inhibitory protein. in Oncogene 2008
Human Polyclonal DDX3X Primary Antibody for EIA, IF - ABIN499730
Linder, Lasko, Ashburner, Leroy, Nielsen, Nishi, Schnier, Slonimski: Birth of the D-E-A-D box. in Nature 1989
Data show that knockdown of RNA helicase (show DDX46 Antibodies) DDX3 in breast cancer MCF-7 and MDA-MB-231 cells resulted in decreased proliferation rates.
Data show that high cytoplasmic DEAD-box helicase 3 (DDX3) expression correlated with nuclear beta-catenin (show CTNNB1 Antibodies) expression, a marker of activated Wnt (show WNT2 Antibodies) signaling.
Our results suggest that the intrinsically disordered N-terminal domain of DDX3 regulates its functions in translation by acting prior to the recruitment of the 43S pre-initiation complex onto the viral 5'-UTR (show UTS2R Antibodies).
The results do not support our hypothesis that common germline genetic variants in the DDX3X genes is associated with the risk of developing medulloblastoma.
analysis of the structural and functional core of the DDX3 subfamily of DEAD-box proteins
The DDX3 may participate in antiviral innate immunity, at least in part, by translational control of interferon (show IFNA Antibodies)-induced protein kinase (show CDK7 Antibodies) (PACT (show RBBP6 Antibodies)).
As such, DDX3 has been shown to play roles both upstream and downstream of I-kappa beta kinase epsilon (IKKepsilon (show IKBKE Antibodies))/TANK-binding kinase 1 (show TBK1 Antibodies), leading to IFN-beta (show IFNB1 Antibodies) production.
Data show that DEAD-box helicase 3 (DDX3) had a significant prognostic predictive power in colorectal cancer at both RNA and protein level.
Taken together, our result demonstrates that Ketorolac salt is a newly discovered bioactive compound against DDX3 and this compound can be used as an ideal drug candidate to treat DDX3 associated oral cancer.
Loss of DDX3 function either by shRNA or by RK-33 impaired Wnt (show WNT2 Antibodies) signaling through disruption of the DDX3-beta-catenin (show CTNNB1 Antibodies) axis and inhibited non-homologous end joining-the major DNA repair pathway in mammalian somatic cells.
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which interacts specifically with hepatitis C virus core protein resulting a change in intracellular location. This gene has a homolog located in the nonrecombining region of the Y chromosome. The protein sequence is 91% identical between this gene and the Y-linked homolog. Alternative splicing results in multiple transcript variants.
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked
, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3
, ATP-dependent RNA helicase DDX3X-like
, ATP-dependent RNA helicase DDX3X
, DEAD box protein 3, X-chromosomal
, DEAD box, X isoform
, DEAD/H box-3
, helicase like protein 2
, helicase-like protein 2
, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked
, ATP-dependent RNA helicase DDX3Y
, DEAD (Asp-Glu-Ala-Asp) box polypeptide 3 Y-linked
, D-E-A-D (aspartate-glutamate-alanine-aspartate) box polypeptide 3
, D1Pas1-related sequence 2
, DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide 3
, DEAD box RNA helicase DEAD3
, DEAD-box protein 3 (DEAD-box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1PAS1 related sequence 2)
, embryonic RNA helicase
, fibroblast growth factor inducible 14