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anti-Dual Specificity Phosphatase 10 (DUSP10) Antibodies

Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. Additionally we are shipping Dual Specificity Phosphatase 10 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DUSP10 11221 Q9Y6W6
DUSP10 63953 Q9ESS0
DUSP10 63995  
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Top anti-Dual Specificity Phosphatase 10 Antibodies at antibodies-online.com

Showing 10 out of 94 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-DUSP10 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: THP-1 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Goat Un-conjugated ELISA, WB ABIN184694 staining (0.5µg/ml) of Human Liver lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Cow Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated WB DUSP10 Antibody (Center) (ABIN1881272) western blot analysis in A375 cell line lysates (35 µg/lane). This demonstrates the DUSP10 antibody detected the DUSP10 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-DUSP10 Pab (ABIN392871) in CEM cell line tissue lysate (35 µg/lane). DUSP10(arrow) was detected using the purified polyclonal antibody (1:60 dilution). Western blot analysis of anti-DUSP10 Pab (ABIN392871) in mouse heart tissue lysates (35 µg/lane). DUSP10(arrow) was detected using the purified polyclonal antibody (1:60 dilution). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded A549 xenograft, using DUSP10, antibody at 1:100 dilution. ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed A431, using DUSP10, antibody at 1:200 dilution. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Mouse Un-conjugated ELISA, WB DUSP10 polyclonal antibody (A01), Lot # 050928JC01 Western Blot analysis of DUSP10 expression in 293 . Western Blot detection against Immunogen (41.51 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details

DUSP10 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-Dual Specificity Phosphatase 10 Antibodies

  1. Human Polyclonal DUSP10 Primary Antibody for WB - ABIN1881272 : Tephly, Carter: Asbestos-induced MKP-3 expression augments TNF-alpha gene expression in human monocytes. in American journal of respiratory cell and molecular biology 2008 (PubMed)
    Show all 5 references for ABIN1881272

  2. Human Polyclonal DUSP10 Primary Antibody for EIA, IHC (p) - ABIN360788 : Tanoue, Moriguchi, Nishida: Molecular cloning and characterization of a novel dual specificity phosphatase, MKP-5. in The Journal of biological chemistry 1999 (PubMed)
    Show all 4 references for ABIN360788

  3. Human Polyclonal DUSP10 Primary Antibody for ELISA, WB - ABIN564881 : Wang, Daouti, Li, Wen, Rizzo, Higgins, Packman, Rosen, Boylan, Heimbrook, Niu: Identification of the MEK1(F129L) activating mutation as a potential mechanism of acquired resistance to MEK inhibition in human cancers carrying the B-RafV600E mutation. in Cancer research 2011 (PubMed)

  4. Human Polyclonal DUSP10 Primary Antibody for WB - ABIN2785082 : Teng, Huang, Meng: Several dual specificity phosphatases coordinate to control the magnitude and duration of JNK activation in signaling response to oxidative stress. in The Journal of biological chemistry 2007 (PubMed)

More Antibodies against Dual Specificity Phosphatase 10 Interaction Partners

Human Dual Specificity Phosphatase 10 (DUSP10) interaction partners

  1. Increased Dusp10 expression is associated with better survival rate in colorectal cancer patients.

  2. Data suggest that vitamin D receptor (show VDR Antibodies) target genes (DUSP10; THBD (show THBD Antibodies), thrombomodulin (show THBD Antibodies); NRIP1 (show NRIP1 Antibodies), nuclear receptor interacting protein 1 (show NRIP1 Antibodies); TRAK1 (show TRAK1 Antibodies), trafficking protein kinesin binding 1 (show TRAK1 Antibodies)) can be used as markers for individual's response to vitamin D3 supplements.

  3. Certain mutations in DUSP10 correlate with the incidence of colorectal cancer(CRC). Thus, the function of the DUSP10 gene product may contribute toward CRC in the Han Chinese population.

  4. Single nucleotide polymorphism in DUSP10 gene is associated with celiac disease.

  5. Depletion of miR (show MLXIP Antibodies)-181 family members by miRNA inhibitors enhanced the expression of MKP-5 and suppressed the phosphorylation of p38 MAPK (show MAPK14 Antibodies) after exposure to PAHs, which promotes cancer cell migration.

  6. Data indicate that the activities of phosphoprotein phosphatases MKP5 and MKP7 (show DUSP16 Antibodies) were determined in the system.

  7. MKP-5 interacts with ERK (show EPHB2 Antibodies), retains it in the cytoplasm, suppresses its activation and downregulates ERK (show EPHB2 Antibodies)-dependent transcription.

  8. A distinct interaction mode revealed by the crystal structure of the kinase p38alpha (show MAPK14 Antibodies) with the MAPK (show MAPK1 Antibodies) binding domain of the phosphatase MKP5.

  9. DUSPs 10 and 16 are positive regulators of activation, apparently acting by modulating cross-talk between the p38 (show CRK Antibodies) and ERK (show EPHB2 Antibodies) pathways.

  10. a function for ASC (show PYCARD Antibodies) that is distinct from the inflammasome in modulating MAPK (show MAPK1 Antibodies) activity and chemokine (show CCL1 Antibodies) expression and further identify DUSP10 as a novel ASC (show PYCARD Antibodies) target.

Mouse (Murine) Dual Specificity Phosphatase 10 (DUSP10) interaction partners

  1. DUSP10 regulates intestinal epithelial cell growth and colorectal tumorigenesis.

  2. In mouse macrophages, MKP-5 down-regulates the release of inflammatory mediators by controlling p38 MAPK (show MAPK14 Antibodies) activity

  3. These results suggest that p38 (show CRK Antibodies) phosphorylation is controlled by DUSP10 expression.

  4. MAPK (show MAPK1 Antibodies) phosphotase 5 deficiency contributes to protection against blood-stage Plasmodium yoelii 17XL infection in mice.

  5. MKP-5 is an essential negative regulator of the promyogenic actions of the MAPKs and may serve as a target to promote muscle stem cell function in the treatment of degenerative skeletal muscle diseases

  6. MKP5 deficiency significantly reduces foam cell formation.

  7. MKP5 is crucial to homeostatic regulation of MAPK (show MAPK1 Antibodies) activation in inflammatory responses.

  8. a function for ASC (show STS Antibodies) that is distinct from the inflammasome in modulating MAPK (show MAPK1 Antibodies) activity and chemokine (show CCL1 Antibodies) expression and further identify DUSP10 as a novel ASC (show STS Antibodies) target.

  9. MKP5 has a principal function in both innate and adaptive immune responses, and represents a novel target for therapeutic intervention of immune diseases

  10. The results show an earlier unrecognized and non-redundant function of MKP-5 in restraining p38 MAPK (show MAPK14 Antibodies)-mediated neutrophil oxidant production, thereby preventing lipopolysaccharide-induced vascular injury.

Dual Specificity Phosphatase 10 (DUSP10) Antigen Profile

Protein Summary

Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAPK superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAPKs, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK, but not MAPK/ERK. Its subcellular localization is unique\; it is evenly distributed in both the cytoplasm and the nucleus. This gene is widely expressed in various tissues and organs, and its expression is elevated by stress stimuli. Three transcript variants encoding two different isoforms have been found for this gene.

Gene names and symbols associated with DUSP10

  • dual specificity phosphatase 10 (DUSP10) antibody
  • dual specificity phosphatase 10 (LOC100227773) antibody
  • dual specificity phosphatase 10 (Dusp10) antibody
  • 2610306G15Rik antibody
  • AI158871 antibody
  • DUSP10 antibody
  • Mkp-5 antibody
  • Mkp5 antibody

Protein level used designations for DUSP10

dual specificity protein phosphatase 10 , dual specificity phosphatase 10 , dual specificity protein phosphatase 10-like , dual specificity phosphatase MKP-5 , map kinase phosphatase 5 , mitogen-activated protein kinase phosphatase 5 , serine/threonine specific protein phosphatase , MAP kinase phosphatase 5

GENE ID SPECIES
421340 Gallus gallus
469145 Pan troglodytes
488673 Canis lupus familiaris
705056 Macaca mulatta
100018106 Monodelphis domestica
100081167 Ornithorhynchus anatinus
100352279 Oryctolagus cuniculus
100411494 Callithrix jacchus
100451135 Pongo abelii
100478038 Ailuropoda melanoleuca
100517416 Sus scrofa
100227773 Taeniopygia guttata
100588389 Nomascus leucogenys
11221 Homo sapiens
63953 Mus musculus
63995 Rattus norvegicus
541175 Bos taurus
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