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anti-Ezrin (EZR) Antibodies

The cytoplasmic peripheral membrane protein encoded by EZR functions as a protein-tyrosine kinase substrate in microvilli. Additionally we are shipping Ezrin Kits (41) and Ezrin Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
EZR 7430 P15311
EZR 22350 P26040
EZR 54319 P31977
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Top anti-Ezrin Antibodies at

Showing 10 out of 398 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Mouse Un-conjugated IHC (p), IP, WB Formalin fixed paraffin embedded human lung stained with Ezrin antibody. ABIN115201 0.5 mL Log in to see 6 to 8 Days
Dog Goat Un-conjugated EIA, IHC (p), WB 20 μg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 2 to 3 Days
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from 293 cells treated with UV 15', using Ezrin (Phospho-Tyr146) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HeLa/HepG2/K562 cells, using Ezrin (Ab-146) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
Human Goat Un-conjugated IHC, ELISA, WB ABIN185664 (1µg/ml) staining of Human Placenta lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
Dog Mouse Un-conjugated IF, IP, IHC, WB Western blot analysis of Ezrin on MDCK lysate. Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of anti-Ezrin. Immunofluorescent staining of HeLa cells. 50 μg Log in to see 5 to 6 Days
Human Rabbit Un-conjugated WB 0.1 mL Log in to see 6 to 8 Days
Human Rabbit Un-conjugated WB 0.1 mL Log in to see 6 to 8 Days
Human Rabbit Un-conjugated WB 0.1 mL Log in to see 6 to 8 Days

EZR Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Ezrin Antibodies

  1. Dog (Canine) Monoclonal EZR Primary Antibody for IF, IP - ABIN968057 : Anastasiadis, Moon, Thoreson, Mariner, Crawford, Zheng, Reynolds: Inhibition of RhoA by p120 catenin. in Nature cell biology 2001 (PubMed)
    Show all 5 references for ABIN968057

  2. Cow (Bovine) Monoclonal EZR Primary Antibody for IHC (p), IP - ABIN115202 : Turunen, Wahlstroem, Vaheri: Ezrin has a COOH-terminal actin-binding site that is conserved in the ezrin protein family. in The Journal of cell biology 1994 (PubMed)
    Show all 5 references for ABIN115202

  3. Human Polyclonal EZR Primary Antibody for WB - ABIN197258 : Wang, Pfeiffer, Gaarde: Activation of SRC tyrosine kinases in response to ICAM-1 ligation in pulmonary microvascular endothelial cells. in The Journal of biological chemistry 2003 (PubMed)
    Show all 4 references for ABIN197258

  4. Human Polyclonal EZR Primary Antibody for WB - ABIN197426 : Fievet, Gautreau, Roy, Del Maestro, Mangeat, Louvard, Arpin: Phosphoinositide binding and phosphorylation act sequentially in the activation mechanism of ezrin. in The Journal of cell biology 2004 (PubMed)
    Show all 4 references for ABIN197426

  5. Human Polyclonal EZR Primary Antibody for WB - ABIN196942 : Zhou, Zhu, Kodani, Hauser, Yao, Forte: Phosphorylation of ezrin on threonine 567 produces a change in secretory phenotype and repolarizes the gastric parietal cell. in Journal of cell science 2005 (PubMed)
    Show all 2 references for ABIN196942

  6. Human Polyclonal EZR Primary Antibody for ELISA, WB - ABIN1533047 : Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: The DNA sequence and analysis of human chromosome 6. ... in Nature 2003 (PubMed)

  7. Dog (Canine) Polyclonal EZR Primary Antibody for EIA, IHC (p) - ABIN782990 : Stanasila, Abuin, Diviani, Cotecchia: Ezrin directly interacts with the alpha1b-adrenergic receptor and plays a role in receptor recycling. in The Journal of biological chemistry 2006 (PubMed)

More Antibodies against Ezrin Interaction Partners

Human Ezrin (EZR) interaction partners

  1. Ezrin protein is highly expressed in human PHC (show SLC25A3 Antibodies) tissue which can be used for the prediction of metastasis disease.

  2. results show that the activation of the ezrin-pAkt signaling axis is associated with the more aggressive clinicopathological features of PPA compared with LPA

  3. Ezrin and p65 (show GORASP1 Antibodies) interactions in MDA-MB-231 cells were confirmed using co-immunoprecipitation.

  4. the distribution of NHERF1 (show SLC9A3R1 Antibodies) in ovarian cancer and reveals a different regulation of NHERF1 (show SLC9A3R1 Antibodies) and EZRIN expression in ovarian tumors which represents the complexity of the molecular changes of this disease

  5. Phosphorylation of ezrin together with its binding to phosphatidylinositol-4,5-bisphosphate tethers the F508del CFTR to the actin cytoskeleton, stabilizing it on the apical membrane and rescuing the sub-membrane compartmentalization of cAMP and activated PKA.

  6. Data show that gene silence of ezrin inhibits the proliferation and invasion of prostate cancer PC-3 (show PCSK1 Antibodies) cells, meanwhile the level of E-cadherin (show CDH1 Antibodies) is upregulated and N-cadherin (show CDH2 Antibodies) is downregulated.

  7. Knockdown of ezrin in HUVECs significantly induced the morphogenetic changes and cytoskeletal reorganization of the transfected cells, and also reduced cell migration and angiogenesis capacity in vitro.

  8. High EZRIN expression is associated with prostate cancer.

  9. Elevated Ezrin expression is associated with a poor prognosis in a variety of solid tumors.

  10. These findings suggest that ezrin-EGFR (show EGFR Antibodies) interaction augments oncogenic functions of EGFR (show EGFR Antibodies) and that targeting ezrin may provide a potential novel approach to overcome erlotinib resistance in non-small cell lung cancer cells

Cow (Bovine) Ezrin (EZR) interaction partners

  1. Ezrin and CK18 (show KRT18 Antibodies) are downregulated during implantation in cattle. The expression changes represent a temporal depolarization, which could be important for an establishment of bovine pregnancy.

  2. Ezrin-dependent, membrane-specific translocation and activation of calpain by VEGF (show VEGFA Antibodies) precedes AMPK (show PRKAA1 Antibodies) and AKT (show AKT1 Antibodies)-dependent phosphorylation of eNOSs1179 and production of NO.

Mouse (Murine) Ezrin (EZR) interaction partners

  1. Ezrin may play a role in regulating lymphatic metastasis in hepatocellular carcinoma and might be inversely associated with A7 expression.

  2. Augmented hypertension-induced glomerular capillary injury in mice lacking CLIC5 results from abrogation of Rac1-dependent Pak and ezrin activation, perhaps reducing the tensile strength of the podocyte actin cytoskeleton.

  3. Data, including data from studies in knockout mice, suggest that VDR (vitamin D receptor) regulates expression of ezrin in enterocytes; VDR (show CYP27B1 Antibodies) appears not to be involved in morphology of tight junctions and absorption of large molecules in enterocytes.

  4. Lack of ezrin not only causes achlorhydria and hypergastrinemia but also changes the structure of gastric glands, with severe perturbation of the secretory membranes of parietal cells.

  5. our study demonstrates that ezrin is a novel regulator of IL-10 (show IL10 Antibodies) production by B cells

  6. Merlin (show NF2 Antibodies) and Ezrin are components of a mechanism where mechanical forces associated with cell junctions are transduced across the cell cortex via cortical actomyosin cytoskeleton to control lateral mobility and activity of epidermal growth factor receptor (show EGFR Antibodies).

  7. Dysfunction of ezrin mimics important aspects of the pathological mechanisms responsible for cholangiopathies

  8. We hypothesize that polyvalent electrostatic interactions are responsible for the assembly of CD44 (show CD44 Antibodies) clusters and the multimeric PIP2-CD44 (show CD44 Antibodies)-Ezrin complexes.

  9. These results indicate that ezrin is required for uptake of hypotaurine from maternal serum by placental trophoblasts, and plays an important role in fetal growth.

  10. These data altogether suggest a novel role of ezrin in the neuritogenesis of the cultured cortical neurons through down-regulation of RhoA (show RHOA Antibodies) activity.

Pig (Porcine) Ezrin (EZR) interaction partners

  1. The cytoskeletal linker protein (show LAT Antibodies) ezrin plays a significant role in hypothermic preservation injury in renal epithelia.

  2. Coexpression of ezrin with Eps8 promotes the formation of membrane ruffles and tufts of microvilli, whereas expression of ezrin and Eps8L1a induces the clustering of actin-containing structures at the cell surface.

  3. These findings reveal that direct ezrin interactions promote PTH1R apical localization and signaling in LLC-PK1 cells.

Rabbit Ezrin (EZR) interaction partners

  1. Spatial control of proton pump H,K-ATPase (show ATP1A1 Antibodies) docking at the apical membrane by phosphorylation-coupled ezrin-syntaxin 3 (show STX3 Antibodies) interaction.

  2. 1) NHE3 (show SLC9A3 Antibodies) basal activity is regulated by a signaling complex that is controlled by sequential effects of two kinases, Akt (show AKT1 Antibodies) and GSK-3 (show GSK3b Antibodies), which act on a Ser (show SIGLEC1 Antibodies) cluster in the same NHE3 (show SLC9A3 Antibodies) C-terminal domain that binds ezrin

  3. Ezrin-mediated F-actin interaction with the epithelial cell may direct membrane recruitment and cytoskeletal surface extension.

  4. relatively high turnover of ezrin T567 phosphorylation was observed in all three epithelia (gastric, kidney and intestine).

Arabidopsis thaliana Ezrin (EZR) interaction partners

  1. VLN2 and VLN3 act redundantly in sclerenchyma development via bundling of actin filaments.

  2. Data indicate that the construction of actin collars was affected in vln2 vln5 double mutantpollen tubes.

  3. VLN2 and VLN3 play a role in actin filament organization in Arabidopsis.

Ezrin (EZR) Antigen Profile

Protein Summary

The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.

Gene names and symbols associated with anti-Ezrin (EZR) Antibodies

  • ezrin (EZR) antibody
  • ezrin b (ezrb) antibody
  • ezrin (ezr) antibody
  • moesin (msn) antibody
  • ezrin (Ezr) antibody
  • villin 2 (VLN2) antibody
  • ATVLN2 antibody
  • AW146364 antibody
  • CVIL antibody
  • CVL antibody
  • ezr antibody
  • p81 antibody
  • R75297 antibody
  • T11A7.16 antibody
  • T11A7_16 antibody
  • Vil2 antibody
  • villin 2 antibody
  • wu:fc05c03 antibody
  • wu:fj31d06 antibody

Protein level used designations for anti-Ezrin (EZR) Antibodies

villin 2 , cb567 , ezrin2 , villin 2 (ezrin) , cytovillin 2 , p81 , villin-2 , cytovillin

100059467 Equus caballus
561589 Danio rerio
595017 Xenopus (Silurana) tropicalis
100145669 Xenopus (Silurana) tropicalis
7430 Homo sapiens
281574 Bos taurus
22350 Mus musculus
54319 Rattus norvegicus
484056 Canis lupus familiaris
100152815 Sus scrofa
100718943 Cavia porcellus
395701 Gallus gallus
100008846 Oryctolagus cuniculus
101837567 Mesocricetus auratus
818773 Arabidopsis thaliana
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