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anti-G Protein-Coupled Receptor Kinase 5 (GRK5) Antibodies

GRK5 encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. Additionally we are shipping G Protein-Coupled Receptor Kinase 5 Proteins (11) and G Protein-Coupled Receptor Kinase 5 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GRK5 2869 P34947
GRK5 14773 Q8VEB1
GRK5 59075 Q62833
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Top anti-G Protein-Coupled Receptor Kinase 5 Antibodies at antibodies-online.com

Showing 10 out of 112 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-GRK5 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Human brain Sample Type: Lane 1:241 µg mouse left ventricle heart lysate Primary Antibody Dilution: 1:0000Secondary Antibody: Anti-rabbit-HRP Secondary Antibody Dilution: 1:0000 Color/Signal Descriptions: GRK5  Gene Name: Kathleen Gabrielson Submitted by: 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB (LEFT)Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (RIGHT)Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with GRK5 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Western blot analysis of anti-GRK5 Pab in HeLa cell lysate (Lane 1) and mouse brain tissue lysate (Lane 2). GRK5 (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Chicken Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC (p), WB Anti- GRK5 Picoband antibody,IHC(P) IHC(P): Human Placenta Tissue Anti- GRK5 Picoband antibody,IHC(P) IHC(P): Mouse Lung Tissue 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-GRK5 Pab (ABIN390988) in HeLa cell lysate (Lane 1) and mouse brain tissue lysate (Lane 2). GRK5 (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HeLa/HepG2/HuvEc cells, using GRK5 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC (p) Anti-GRK5 antibody  ABIN1048924 IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p) Anti-GRK5 antibody  ABIN1048923 IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details

GRK5 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-G Protein-Coupled Receptor Kinase 5 Antibodies

  1. Human Polyclonal GRK5 Primary Antibody for EIA, IHC (p) - ABIN359046 : Pronin, Morris, Surguchov, Benovic: Synucleins are a novel class of substrates for G protein-coupled receptor kinases. in The Journal of biological chemistry 2000 (PubMed)
    Show all 5 references for ABIN359046

  2. Chicken Polyclonal GRK5 Primary Antibody for WB - ABIN2785866 : Liggett, Cresci, Kelly, Syed, Matkovich, Hahn, Diwan, Martini, Sparks, Parekh, Spertus, Koch, Kardia, Dorn: A GRK5 polymorphism that inhibits beta-adrenergic receptor signaling is protective in heart failure. in Nature medicine 2008 (PubMed)

More Antibodies against G Protein-Coupled Receptor Kinase 5 Interaction Partners

Zebrafish G Protein-Coupled Receptor Kinase 5 (GRK5) interaction partners

  1. GRK2 (show ADRBK1 Antibodies) and GRK5 control cardiac function as well as morphogenesis during development although with different morphological outcomes.

  2. Results identify GRK5/6 as novel kinases for the single transmembrane receptor LRP6 (show LRP5 Antibodies) during Wnt (show WNT2 Antibodies) signaling.

Human G Protein-Coupled Receptor Kinase 5 (GRK5) interaction partners

  1. Suggest a common regulatory pattern for the beta(1)-AR/GRK5 which is independent of cellular type or pathology.

  2. We demonstrated that the SNPs and the related haplotypes of GRK5 could play a central role in predisposing Parkinson disease patients to cognitive impairment.

  3. Thus, we provided new insight into the function of GRKs in agonist-unstimulated GPCR (show NMUR1 Antibodies) trafficking using a recombinant AM1 receptor and further determined the region of the CLR C-tail responsible for this GRK (show GRK4 Antibodies) function.

  4. ADORA2A (show ADORA2A Antibodies) and GRK5 gene variants may influence the etiology of malaria infection.

  5. A significant difference in the frequency of GRK5 polymorphism was found between Takotsubo cardiomyopathy patients and controls, supporting a genetic predisposition to this cardiac syndrome.

  6. Specific patterns of altered heart GRK5 gene expression were found in models of cardiac hypertrophy.

  7. This study sought to identify the distributed characteristics of these variant genotypes in Chinese population, and influence of GRK5 and ADRB1 (show ADRB1 Antibodies) polymorphisms on systolic heart failure morbidity.

  8. GRK5 is found in a partially closed state with its kinase domain C-tail forming novel interactions with nucleotide and the N-lobe (show LTF Antibodies).

  9. G protein-coupled receptor kinase 5 gene (show GPD1 Antibodies) polymorphisms may have a role in postoperative atrial fibrillation after coronary artery bypass grafting in patients receiving beta-blockers

  10. These data suggest that increased GRK5 expression may contribute to the pathophysiology of schizophrenia.

Mouse (Murine) G Protein-Coupled Receptor Kinase 5 (GRK5) interaction partners

  1. MOR (show OPRM1 Antibodies) phosphorylation is regulated by agonist-selective recruitment of distinct GRK (show GRK4 Antibodies) isoforms that influence different opioid-related behaviors. Modulation of GRK5 function could serve as a new approach for preventing addiction to opioids.

  2. GRK5, acting in a kinase independent manner, is a facilitator of NFAT (show NFATC1 Antibodies) activity and part of a DNA-binding complex responsible for pathological hypertrophic gene transcription.

  3. influence of GRK5 on NF-kappaB (show NFKB1 Antibodies) expression and activity

  4. these data identified GRK5 as a positive regulator of insulin (show INS Antibodies) sensitivity.

  5. metoprolol is a biased ligand that selectively activates a G protein-independent and GRK5/beta-arrestin2 (show ARRB2 Antibodies)-dependent pathway, and induces cardiac fibrosis.

  6. These results define myocyte GRK5 as a critical regulator of pathological cardiac growth after ventricular pressure overload, supporting its role as an endogenous (patho)-physiological HDAC (show HDAC3 Antibodies) kinase.

  7. these results suggest that GRK5 is an important regulator of adipogenesis and is crucial for the development of diet-induced obesity.

  8. GRK5 regulates IL-12p40 and G-CSF (show CSF3 Antibodies) via a mechanism that is common to both MyD88 (show MYD88 Antibodies) and TRIF (show RNF138 Antibodies).

  9. G protein-coupled receptor kinase-5 attenuates atherosclerosis by regulating receptor tyrosine kinases and 7-transmembrane receptors.

  10. GRK5 is a positive regulator of TLR4 (show TLR4 Antibodies)-induced IkappaBalpha (show NFKBIA Antibodies)-NFkappaB pathway as well as a key modulator of LPS (show TLR4 Antibodies)-induced inflammatory response.

Cow (Bovine) G Protein-Coupled Receptor Kinase 5 (GRK5) interaction partners

  1. GRK5, acting in a kinase independent manner, is a facilitator of NFAT (show NFATC1 Antibodies) activity and part of a DNA-binding complex responsible for pathological hypertrophic gene transcription.

  2. potential GRK5 interacting proteins and the association of GRK5 with DDB1 in cell and the regulation of GRK5 level by DDB1-CUL4 ubiquitin ligase complex-dependent proteolysis pathway

  3. GRK5 overexpression causes nuclear accumulation of IkappaB alpha, leading to the inhibition of NFkappaB transcriptional activity.

G Protein-Coupled Receptor Kinase 5 (GRK5) Antigen Profile

Protein Summary

This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs).

Gene names and symbols associated with GRK5

  • G protein-coupled receptor kinase 5 (GRK5) antibody
  • G protein-coupled receptor kinase 5 (grk5) antibody
  • G protein-coupled receptor kinase 4 (grk4) antibody
  • G protein-coupled receptor kinase 5 (Grk5) antibody
  • DKFZp468J1119 antibody
  • Gprk5 antibody
  • GRK5 antibody
  • si:dkey-171l20.1 antibody
  • zgc:153020 antibody

Protein level used designations for GRK5

G protein-coupled receptor kinase 5 , GRK5 , FP2025 , g protein-coupled receptor kinase GRK5

GENE ID SPECIES
100065919 Equus caballus
550070 Xenopus (Silurana) tropicalis
560806 Danio rerio
100171722 Pongo abelii
100593251 Nomascus leucogenys
560761 Danio rerio
2869 Homo sapiens
14773 Mus musculus
59075 Rattus norvegicus
281801 Bos taurus
423929 Gallus gallus
486915 Canis lupus familiaris
100152937 Sus scrofa
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