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GATA2 encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. Additionally we are shipping GATA2 Kits (21) and GATA2 Proteins (10) and many more products for this protein.
Showing 10 out of 122 products:
Chicken Polyclonal GATA2 Primary Antibody for IHC, WB - ABIN2777458
Tsuzuki, Kitajima, Nakano, Glasow, Zelent, Enver: Cross talk between retinoic acid signaling and transcription factor GATA-2. in Molecular and cellular biology 2004
Show all 6 references for ABIN2777458
Human Monoclonal GATA2 Primary Antibody for IF, WB - ABIN394181
Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010
Show all 5 references for ABIN394181
Human Polyclonal GATA2 Primary Antibody for ICC, IF - ABIN4313645
Chiang, Wang, Fazli, Qi, Gleave, Collins, Gout, Wang: GATA2 as a potential metastasis-driving gene in prostate cancer. in Oncotarget 2014
Show all 2 references for ABIN4313645
Human Polyclonal GATA2 Primary Antibody for EIA, WB - ABIN453049
Pan, Minegishi, Harigae, Yamagiwa, Minegishi, Akine, Yamamoto: Identification of human GATA-2 gene distal IS exon and its expression in hematopoietic stem cell fractions. in Journal of biochemistry 2000
the results of this study demonstrated that high expression of GATA2 is correlated with worse survival outcomes in KRAS mutant colorectal cancer patients
Letter/Case Report: frameshift mutation in GATA2 resulting in Emberger syndrome in Korean patient.
GATA2 was differentially expressed between Fibromyalgia patients and healthy controls.
we screened 995 transcription factor genes and revealed that CITED2 (show CITED2 Antibodies) acts as a GATA-2 activator in human hematopoietic cells. These results provide novel insights into and further identify the regulatory mechanism of GATA-2
GATA2-to-GATA1 (show GATA1 Antibodies) switch is prevalent at dynamic enhancers and drives erythroid enhancer commissioning
results demonstrated that GATA2 single nucleotide polymorphism rs2335052 is an independent predictor for prognosis of colorectal cancer patients.
Data show that the Lim domain only 2 (LMO2 (show LMO2 Antibodies)) regulatory element (element-25) region consists of transcription factor GATA2-binding myeloid ennhancer and RUNX protein-binding T-cell repressor.
High GATA2 promotes glioma progression through EGFR (show EGFR Antibodies)/ERK/Elk-1 (show ELK1 Antibodies) pathway.
In children and adults with severe GM-CSF (show CSF2 Antibodies) negative PAP a close cooperation between pneumologists and hemato-oncologists is needed to diagnose the underlying diseases, some of which are caused by mutations of transcription factor GATA2.
GATA1 (show GATA1 Antibodies) and GATA2 are involved in clear cell renal cell carcinoma (show MOK Antibodies) biology possibly affecting tumor development and aggressiveness.
bcar3 gene is expressed downstream of Gata2 during gastrulation, and is co-expressed with gata2 but is more broadly expressed during later development; its binding partner, bcar1 (show BCAR1 Antibodies) shows overlapping expression patterns
results are consistent with a model in which GATA2 contributes to inhibition of canonical Wnt (show WNT2 Antibodies) signaling
these findings, strongly implicate Dlx3 in the regulation of non-neural competence, and show that GATA2 contributes to non-neural competence but is not sufficient to promote it ectopically.
Studies suggest a two-component model for the binding of CBTF (show MMP4 Antibodies) with gata2 promoter, requiring both a CCAAT and A-form DNA, and the double stranded RNA binding domains (dsRBDs) of CBTF (show MMP4 Antibodies) component Xilf3 (show MMP4 Antibodies) must be active for both binding to the promoter.
Gata-2 is a transcriptional target downstream of BMPs within ectodermal cells, while activation of the CaM (show Calm2 Antibodies) KIV signaling pathway alters GATA-2 function posttranslationally, by inhibiting its acetylation.
GATA2 and/or GATA3 (show GATA3 Antibodies) are involved in the regulation of trophoblast-specific gene transcription in bovine trophoblast CT-1 (show SLC6A8 Antibodies) cells
we identified important roles for the GATA-2 C-ZnF in bone marrow hematopoiesis via control of c-Kit expression and HSC/HSPC survival.
Data show that transforming growth factor beta (TGFbeta (show TGFB1 Antibodies))-induced changes in Gata2 transcription factor and cyclin-dependent kinase inhibitor 1C (P57 (show CDKN1C Antibodies)) expression in hematopoietic progenitors are conveyed through Smad (show SMAD1 Antibodies) signaling via Smad4 protein (show SMAD4 Antibodies).
Gata2 as a crucial rheostat of mesenchymal stem cell fate to control osteoblast and adipocyte lineage development.
Sox17 (show SOX17 Antibodies) inhibition of Runx1 (show RUNX1 Antibodies) and Gata2 maintains endothelial fate in endothelial-to-haematopoietic transition
LSD1 (show KDM1A Antibodies) mediates erythroid differentiation, via epigenetic modification of the GATA-2 locus.
Results provide new insights into the selective roles of Gata2 within the genetic model of V2 interneurons development and in particular on the hierarchy between V2-transcription factors
Conditional Gata2 deletion in mice revealed that GATA2 is required for both development and maintenance of lymphovenous and lymphatic vessel valves.
These results suggest that Setd8 (show SETD8 Antibodies) is an important regulator of erythroid maturation that works in part through repression of Gata2 expression.
FLI1 (show FLI1 Antibodies) and GATA2 are upstream regulators of SMAD1 (show SMAD1 Antibodies) and SMAD5 (show SMAD5 Antibodies) expression in endothelial cells.
these results indicate that GATA2 maintains cellular identity in a subpopulation of mast cells, whereas it plays a fundamental role as a positive regulator of mast cell-specific genes throughout development of this cell lineage.
This gene encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. The encoded protein plays an essential role in regulating transcription of genes involved in the development and proliferation of hematopoietic and endocrine cell lineages. Alternative splicing results in multiple transcript variants.
GATA binding protein 2
, glutamyl/aspartyl-tRNA(Gln/Asp) amidotransferasesubunit A
, hypothetical protein
, protein GatA2
, GATA2 transcription factor
, endothelial transcription factor GATA-2-like
, endothelial transcription factor GATA-2
, GATA binding factor-2
, GATA-binding factor 2
, transcription factor xGATA-2
, transcription factor NF-E1B
, transcription factor GATA-2
, GATA-binding protein 2
, GATA-bindning protein 2