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anti-GDNF Family Receptor alpha 2 (GFRA2) Antibodies

Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. Additionally we are shipping GFRA2 Proteins (13) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GFRA2 2675 O00451
GFRA2 25136  
GFRA2 14586  
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Top anti-GFRA2 Antibodies at antibodies-online.com

Showing 10 out of 72 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IF, WB Immunocytochemistry of GFR alpha 2 in HeLa cells with AP30362PU-N GFR ... Western blot analysis of GFR alpha 2 in HeLa total cell lysate with AP... 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-GFRA2 Antibody Titration: 0.2-1 ug/mlPositive Contro... Host: Rabbit  Target Name: GFRA2  Sample Tissue: Human Adult Placenta ... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB GFRA2 Antibody (C-term) (ABIN658295) western blot analysis in NCI-H292... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Anti-GDNF-... Formalin-fixed and paraffin embedded human placenta tissue labeled wit... 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IHC (fro), WB 0.1 mg Log in to see 3 to 4 Days
$375.29
Details
Human Rabbit Un-conjugated ICC, ELISA, WB   100 μg Log in to see 15 to 19 Days
$466.62
Details
Human Rabbit Un-conjugated ICC, WB 100 μg Log in to see 8 to 10 Days
$522.50
Details
Human Rabbit Un-conjugated WB GFRA2 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit FITC ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details

GFRA2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
, , ,
Rat (Rattus) , , , ,

Mouse (Murine) , , , ,

Top referenced anti-GFRA2 Antibodies

  1. Human Polyclonal GFRA2 Primary Antibody for ICC, ELISA - ABIN1002346 : Kotzbauer, Lampe, Heuckeroth, Golden, Creedon, Johnson, Milbrandt: Neurturin, a relative of glial-cell-line-derived neurotrophic factor. in Nature 1997 (PubMed)
    Show all 4 references for ABIN1002346

  2. Human Polyclonal GFRA2 Primary Antibody for IHC (fro), WB - ABIN2473789 : Klein, Sherman, Ho, Stone, Bennett, Moffat, Vandlen, Simmons, Gu, Hongo, Devaux, Poulsen, Armanini, Nozaki, Asai, Goddard, Phillips, Henderson, Takahashi, Rosenthal: A GPI-linked protein that interacts with Ret to form a candidate neurturin receptor. in Nature 1997 (PubMed)
    Show all 4 references for ABIN2473789

  3. Human Polyclonal GFRA2 Primary Antibody for EIA, IF - ABIN499885 : Buj-Bello, Adu, Piñón, Horton, Thompson, Rosenthal, Chinchetru, Buchman, Davies: Neurturin responsiveness requires a GPI-linked receptor and the Ret receptor tyrosine kinase. in Nature 1997 (PubMed)
    Show all 4 references for ABIN499885

More Antibodies against GFRA2 Interaction Partners

Human GDNF Family Receptor alpha 2 (GFRA2) interaction partners

  1. GFRA2 variants associated with diabetic neuropathic pain.

  2. The study shows co-localization of RET (show RET Antibodies) with GFRA1 (show GFRA1 Antibodies) and GFRA2 in myenteric ganglia of the adult human colon.

  3. Cyclic AMP (show APRT Antibodies) signalling through PKA but not Epac (show RAPGEF3 Antibodies) is essential for neurturin (show NRTN Antibodies)-induced biphasic ERK1/2 (show MAPK1/3 Antibodies) activation and neurite outgrowths through GFRalpha2 isoforms.

  4. GFRA2 genetic variants, and age, may play a role in susceptibility to tardive dyskinesia.

  5. This study found nominally-significant evidence for interactions between GFRA1 (show GFRA1 Antibodies), 2 and 3 associated with schizophrenia and clozapine response, consistent with the locations of these three genes within linkage regions for schizophrenia.

  6. Both GFR (show RAPGEF5 Antibodies) alpha2a and GFR (show RAPGEF5 Antibodies) alpha2c, but not GFR (show RAPGEF5 Antibodies) alpha2b (show ADRA2B Antibodies), promote neurite outgrowth in transfected Neuro2A cells.

Mouse (Murine) GDNF Family Receptor alpha 2 (GFRA2) interaction partners

  1. Ret (show RET Antibodies) and Gfra2 null mice display comparable early central projection deficits, but Gfra2 null rapidly adapting mechanoreceptors recover later.

  2. STAT3 (show STAT3 Antibodies) phosphorylation by neurturin (show NRTN Antibodies) was found to be mediated specifically by GFRalpha2c and RET9 (show RET Antibodies) isoforms.

  3. Cholinergic innervation of gastric mucosa depends on neurturin (show NRTN Antibodies)-GFRalpha2 signalling but is dispensable for gastrin (show GAST Antibodies) secretion and for basal and maximal acid output

  4. our data demonstrate that RET (show RET Antibodies)/GFRalpha signals are dispensable for thymic T cell development in vivo

  5. Transduction-function role for GFR (show RAPGEF5 Antibodies) alpha2/neurturin (show NRTN Antibodies) signalling in a specific class of sensory neurons.

  6. The cholinergic subpopulation of sympathetic neurons requires GFR alpha 2 signaling for soma size and for growth or maintenance of target innervation.

  7. Demonstrate a role for GFRalpha2-expressing enteric neurons in the downstream signaling of the glucagon (show GCG Antibodies)-like peptides to inhibit GI motility, but not in intestinal growth.

GFRA2 Antigen Profile

Protein Summary

Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with GFRA2

  • DKFZP459C0228 protein (DKFZP459C0228) antibody
  • GDNF family receptor alpha 2 (gfra2) antibody
  • glial cell line derived neurotrophic factor family receptor alpha 2a (gfra2a) antibody
  • GDNF family receptor alpha 2 (GFRA2) antibody
  • GDNF family receptor alpha 2 (Gfra2) antibody
  • glial cell line derived neurotrophic factor family receptor alpha 2 (Gfra2) antibody
  • DKFZP459C0228 antibody
  • GDNFRB antibody
  • gfra2 antibody
  • NRTNR-ALPHA antibody
  • NTNRA antibody
  • NTNRALPHA antibody
  • Retl2 antibody
  • TRNR2 antibody

Protein level used designations for GFRA2

DKFZP459C0228 protein , GFR-alpha-2 , GDNF family receptor alpha-2 , GDNF family receptor alpha 2 , glial cell line derived neurotrophic factor family receptor alpha 2 , GFR alpha 2 , GDNF family receptor alpha-2-like , GDNF receptor beta , GDNFR-alpha-2 , GDNFR-beta , GFR-alpha 2 , NTNR-alpha , PI-linked cell-surface accessory protein , RET ligand 2 , TGF-beta-related neurotrophic factor receptor 2 , TRN receptor, GPI-anchored , glial cell line derived neurotrophic factor receptor, beta , neurturin receptor alpha , GDNF receptor alpha-2 , tyrosine kinase receptor ligand 2 , NRTNR-alpha , GFR alpha-2

GENE ID SPECIES
100189713 Pongo abelii
100127717 Xenopus (Silurana) tropicalis
405794 Danio rerio
100475044 Ailuropoda melanoleuca
2675 Homo sapiens
609172 Canis lupus familiaris
514036 Bos taurus
25136 Rattus norvegicus
395993 Gallus gallus
100171804 Pongo abelii
14586 Mus musculus
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