GFRA2 antibody (AA 360-464)

Catalog No. ABIN1679988

The Rabbit Polyclonal anti-GFRA2 antibody is suitable to detect GFRA2 in samples from Human. It has been validated for WB.

Quick Overview for GFRA2 antibody (AA 360-464) (ABIN1679988)

Target: GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GFRA2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GFRA2 Antibody

Binding Specificity: AA 360-464

Sequence: DVNVSPKGPS FQATQAPRVE KTPSLPDDLS DSTSLGTSVI TTCTSVQEQG LKANNSKELS MCFTELTTNI IPGSNKVIKP NSGPSRARPS AALTVLSVLM LKLAL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 360-464 of human GFRA2 (NP_001486.4).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GFRA2

Target: GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))

Alternative Name: GFRA2

Background: Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene.,GFRA2,GDNFRB,NRTNR-ALPHA,NTNRA,RETL2,TRNR2,Neuroscience,GFRA2

Molecular Weight: 36 kDa/39 kDa/51 kDa

Gene ID: 2675

UniProt: O00451