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HLTF encodes a member of the SWI/SNF family. Additionally we are shipping HLTF Kits (10) and HLTF Proteins (5) and many more products for this protein.
Showing 10 out of 77 products:
Human Polyclonal HLTF Primary Antibody for ICC, IF - ABIN249536
Oh, Gao, Lee, Ceglia, Seo, Zhang, Ahn, Chait, Patel, Kim, Greengard: SMARCA3, a chromatin-remodeling factor, is required for p11-dependent antidepressant action. in Cell 2013
Show all 2 references for ABIN249536
Human Polyclonal HLTF Primary Antibody for ICC, IF - ABIN4319291
Helmer, Foreman, Dertien, Panchoo, Bhakta, Chilton: Role of helicase-like transcription factor (hltf) in the G2/m transition and apoptosis in brain. in PLoS ONE 2013
Show all 2 references for ABIN4319291
Human Polyclonal HLTF Primary Antibody for IP, WB - ABIN151748
Motegi, Liaw, Lee, Roest, Maas, Wu, Moinova, Markowitz, Ding, Hoeijmakers, Myung: Polyubiquitination of proliferating cell nuclear antigen by HLTF and SHPRH prevents genomic instability from stalled replication forks. in Proceedings of the National Academy of Sciences of the United States of America 2008
Cow (Bovine) Polyclonal HLTF Primary Antibody for WB - ABIN2780461
Unk, Hajdú, Fátyol, Hurwitz, Yoon, Prakash, Prakash, Haracska: Human HLTF functions as a ubiquitin ligase for proliferating cell nuclear antigen polyubiquitination. in Proceedings of the National Academy of Sciences of the United States of America 2008
Human Polyclonal HLTF Primary Antibody for ELISA, WB - ABIN184752
Sheridan, Schorpp, Voz, Jones: Cloning of an SNF2/SWI2-related protein that binds specifically to the SPH motifs of the SV40 enhancer and to the HIV-1 promoter. in The Journal of biological chemistry 1995
Cow (Bovine) Polyclonal HLTF Primary Antibody for WB - ABIN2775846
Beausoleil, Jedrychowski, Schwartz, Elias, Villén, Li, Cohn, Cantley, Gygi: Large-scale characterization of HeLa cell nuclear phosphoproteins. in Proceedings of the National Academy of Sciences of the United States of America 2004
Human Polyclonal HLTF Primary Antibody for EIA, WB - ABIN453097
Ding, Descheemaeker, Marynen, Nelles, Carvalho, Carmo-Fonseca, Collen, Belayew: Characterization of a helicase-like transcription factor involved in the expression of the human plasminogen activator inhibitor-1 gene. in DNA and cell biology 1996
HLTF is degraded in lymphocytic cells and macrophages infected with Vpr-expressing HIV-1. Our results reveal a previously unidentified strategy for HIV-1 to antagonize DNA repair in host cells.
HLTF expression is altered in various cancers via two mechanisms: gene silencing through promoter hypermethylation or alternative mRNA splicing, which leads to the expression of truncated proteins that lack DNA repair domains. [review]
HLTF promotes the filling-in of gaps left opposite damaged DNA during replication, and this postreplication repair function depends on its HIRAN domain.
Findings indicate a mechanism of helicase-like transcription factor HLTF-mediated fork reversal and suggest the requirement for distinct fork remodeling activities in the cell.
Study demonstrates a correlation between HLTF expression level and thyroid neoplastic progression where three truncated forms are detected in thyroid carcinoma.
We were able to provide evidence that methylation of HLTF and especially HPP1 detected in serum is strongly correlated with cell death in CRC using LDH as surrogate marker
Results demonstrate that loss of HLTF function promotes the malignant transformation of intestinal or colonic adenomas to carcinomas by inducing genomic instability.
results delineate a previously unknown USP7 (show USP7 Antibodies)-HLTF-PCNA (show PCNA Antibodies) molecular network controlling DNA damage response
HLTF can displace a broad spectrum of proteins such as replication protein A (RPA (show RPA1 Antibodies)), PCNA (show PCNA Antibodies), and replication factor C (RFC (show RFC1 Antibodies)), thereby providing the first example for a protein clearing activity at the stalled replication fork.
HLTF and SHPRH (show SHPRH Antibodies) suppress mutagenesis in a damage-specific manner, preventing mutations induced by UV rays and methyl methanesulfonate.
Prolactin (show PRL Antibodies) dependent Jak2 (show JAK2 Antibodies) phosphorylation of RUSH.
Splice arrays and RT-PCR showed that although most splice variants in RUSH and ATP11B (show ATP11B Antibodies) are conserved in human and rabbit, the RFBP isoform is specific to rabbit.
silencing Hltf during heart organogenesis compromised DNA double-strand break repair, and caused aberrant collagen biogenesis altering the structural network that transmits cardiomyocyte force into muscle contraction
Data show a role of helicase-like transcription factor (hltf) in the G2/m transition and apoptosis in brain
p11 (show S100A10 Antibodies) and AnxA2 (show ANXA2 Antibodies) cooperate to create a unique binding pocket, but the optimal binding condition is not achieved without conformational changes associated with target binding. Upon interaction with the SMARCA3 peptide, both Asp60 in p11 (show S100A10 Antibodies) and Ser12 in AnxA2 (show ANXA2 Antibodies) flip inward toward the peptide-binding groove, forming additional intermolecular hydrogen bonds.
This gene encodes a member of the SWI/SNF family. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein contains a RING finger DNA binding motif. Two transcript variants encoding the same protein have been found for this gene. However, use of an alternative translation start site produces an isoform that is truncated at the N-terminus compared to the full-length protein.
helicase-like transcription factor
, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 3
, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a3
, DNA-binding protein/plasminogen activator inhibitor 1 regulator
, DNA-binding protein/plasminogen activator inhibitor-1 regulator
, RING finger protein 80
, SNF2-like 3
, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3
, sucrose nonfermenting protein 2-like 3
, sucrose nonfermenting-like 3
, RUSH 1
, TNF-response element-binding protein
, helicase-like transcription factor-like protein