You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1) Antibodies

The membrane protein encoded by HCN1 is a hyperpolarization-activated cation channel that contributes to the native pacemaker currents in heart and neurons. Additionally we are shipping HCN1 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HCN1 348980 O60741
HCN1 84390 Q9JKB0
HCN1 15165 O88704
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-HCN1 Antibodies at antibodies-online.com

Showing 10 out of 97 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB HCN1 Antibody (C-term) (ABIN658149) western blot analysis in Hela cell... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IP, IHC, WB rat brain HCN1 Western Blotting. 100 μg Log in to see 3 to 4 Days
$383.90
Details
Rat Mouse Un-conjugated ICC, IHC (p), IP, WB Anti-HCN1 antibody IHC staining of human pancreas, islets of Langerhan... 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Mouse HRP IP, IHC, WB   100 μg Log in to see 3 to 4 Days
$422.40
Details
Human Mouse FITC IP, IHC, WB   100 μg Log in to see 3 to 4 Days
$426.80
Details
Human Mouse Alkaline Phosphatase (AP) IP, IHC, WB   100 μg Log in to see 3 to 4 Days
$429.00
Details
Human Mouse Biotin IP, IHC, WB   100 μg Log in to see 3 to 4 Days
$431.20
Details
Human Mouse PE IP, IHC, WB   100 μg Log in to see 3 to 4 Days
$432.30
Details
Human Mouse Streptavidin IP, IHC, WB   100 μg Log in to see 3 to 4 Days
$433.40
Details
Human Mouse PerCP IP, IHC, WB   100 μg Log in to see 3 to 4 Days
$434.50
Details

HCN1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
, ,
Rat (Rattus) , , , ,
, ,
Mouse (Murine) , , , ,
, ,

Top referenced anti-HCN1 Antibodies

  1. Human Monoclonal HCN1 Primary Antibody for IP, IHC - ABIN2483964 : Zong, Eckert, Yuan, Wahl-Schott, Abicht, Fang, Li, Mistrik, Gerstner, Much, Baumann, Michalakis, Zeng, Chen, Biel: A novel mechanism of modulation of hyperpolarization-activated cyclic nucleotide-gated channels by Src kinase. in The Journal of biological chemistry 2005 (PubMed)

  2. Human Polyclonal HCN1 Primary Antibody for IHC (p), WB - ABIN658149 : Odefrey, Stone, Gurrin, Byrnes, Apicella, Dite, Cawson, Giles, Treloar, English, Hopper, Southey,: Common genetic variants associated with breast cancer and mammographic density measures that predict disease. in Cancer research 2010 (PubMed)

More Antibodies against HCN1 Interaction Partners

Human Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1) interaction partners

  1. A new mode of regulating HCN1 trafficking: through the use of a di-arginine ER retention signal that monitors processing of the channel in the early secretory pathway.

  2. de novo HCN1 point mutations cause a recognizable early-onset epileptic encephalopathy in humans

  3. acute abrogation of HCN1-FLNa (show FLNA Antibodies) interaction in neurons, with the use of decoy peptides that mimic the FLNa (show FLNA Antibodies)-binding domain of HCN1, abolishes the punctate distribution of HCN1 channels in neuronal cell bodies

  4. Studies suggest that HCN1 channels may be therapeutic targets for treatment of depressive disorders.

  5. Wild-type presynaptic HCN1 channel function is persistently decreased following seizures.

  6. HCN1 channels make an important contribution to the maintenance of spontaneous burst activity in embryonic cortical neuron cultures.

  7. Hyperpolarization-activated currents are smaller and slower, input resistances are higher, and membrane time constants are longer in HCN1-deficient than in HCN1-expressing neurons of the ventral cochlear nucleus.

  8. Genetic analysis in 48 Sudden unexpected death in epilepsy cases identified six novel and three previously reported nonsynonymous (amino acid changing) variants in HCN1 , HCN2 (show HCN2 Antibodies), HCN3 (show HCN3 Antibodies) and HCN4 (show HCN4 Antibodies).

  9. increasing cAMP levels in cells antagonized the up-regulation of HCN1 channels mediated by a TRIP8b (show PEX5L Antibodies) construct binding the CNBD exclusively.

  10. Human HCN1 hyperpolarization activated current (Ih) amplitude is rapidly enhanced after establishment of the whole-cell configuration in HEK293 cells.

Mouse (Murine) Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1) interaction partners

  1. in the absence of HCN1-mediated feedback, the amplitude of rod signals remains at high levels for a prolonged period of time, leading to saturation of the retinal pathways.

  2. These results demonstrate that the CB1R (show CNR1 Antibodies)-Ih pathway in the hippocampus is obligatory for the action of cannabinoids on long-term potentiation and spatial memory formation.

  3. Resilience to tinnitus is developed in mice that show a re-emergence of KCNQ2/3 channel activity and a reduction in HCN channel activity.

  4. HCN1, HCN2 (show HCN2 Antibodies), and HCN4 (show HCN3 Antibodies) subunits may have distinct physiological roles in the developing hippocampus.

  5. Forebrain HCN1 channels contribute to hypnotic and amnestic effects of volatile anesthetics, but do not contribute to immobilizing actions.

  6. This study demonstrated that Increased expression of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels in reactive astrocytes following ischemia.

  7. Results suggest that spike-and-wave discharges in an established model of absence epilepsy reduce hippocampal HCN1 expression and function, and that the reduction associates with a spatial learning deficit

  8. Grid fields in HCN1 KO mice display more experience-dependent asymmetry consistent with reports of enhanced long-term potentiation in the absence of HCN1. The loss of HCN1 improves temporal coding via the rate-phase transformation.

  9. We conclude that TRIP8b (show PEX5L Antibodies) in the retina is needed to achieve maximal expression of HCN1.

  10. HCN1 channels in cerebellar Purkinje cells reduce the duration of inhibitory synaptic responses.

HCN1 Antigen Profile

Protein Summary

The membrane protein encoded by this gene is a hyperpolarization-activated cation channel that contributes to the native pacemaker currents in heart and neurons. The encoded protein can homodimerize or heterodimerize with other pore-forming subunits to form a potassium channel. This channel may act as a receptor for sour tastes.

Gene names and symbols associated with HCN1

  • hyperpolarization activated cyclic nucleotide-gated potassium channel 1 (hcn1) antibody
  • hyperpolarization activated cyclic nucleotide-gated potassium channel 1 (HCN1) antibody
  • hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 (Hcn1) antibody
  • hyperpolarization-activated, cyclic nucleotide-gated K+ 1 (Hcn1) antibody
  • BCNG-1 antibody
  • Bcng1 antibody
  • C630013B14Rik antibody
  • HAC-2 antibody
  • HAC2 antibody

Protein level used designations for HCN1

hyperpolarization activated cyclic nucleotide-gated potassium channel 1 , brain cyclic nucleotide gated channel 1 , brain cyclic nucleotide-gated channel 1 , potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 , hyperpolarization-activated cyclic nucleotide-gated channel 1 , rbHCN1 , BCNG-1 , HAC-2 , hyperpolarization-activated cation channel 2

GENE ID SPECIES
100564901 Anolis carolinensis
348980 Homo sapiens
100008732 Oryctolagus cuniculus
84390 Rattus norvegicus
15165 Mus musculus
Selected quality suppliers for anti-HCN1 (HCN1) Antibodies
Did you look for something else?