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anti-Integrin alpha 2 (ITGA2) Antibodies

ITGA2 product belongs to the integrin alpha chain family. Additionally we are shipping Integrin alpha 2 Kits (9) and Integrin alpha 2 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ITGA2 16398 Q62469
ITGA2 170921  
ITGA2 3673 P17301
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Top anti-Integrin alpha 2 Antibodies at antibodies-online.com

Showing 10 out of 338 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse FITC FACS ABIN118698 staining of human peripheral blood platelets. 0.1 mg Log in to see 6 to 8 Days
$412.50
Details
Human Mouse Un-conjugated FACS Staining of human peripheral blood monocytes with MOUSE ANTI HUMAN CD49b (ABIN118700). 0.1 mg Log in to see 6 to 8 Days
$253.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of CD49b / ITGA2 Antibody (C-term) in MDA-MB231 cell line lysates (35ug/lane). ITGA2 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated EIA, FACS, IHC (fro), IHC (p), IP, WB   0.2 mg Log in to see 6 to 8 Days
$500.50
Details
Human Mouse Un-conjugated EIA, FACS, IHC (fro), IP, WB   25 μg Log in to see 6 to 8 Days
$176.00
Details
Human Mouse PE FACS Staining of human peripheral blood platelets with mouse anti human CD49b:RPE (ABIN118701). 100 Tests Log in to see 6 to 8 Days
$434.50
Details
Human Mouse Biotin FACS   25 μg Log in to see 6 to 8 Days
$198.00
Details
Human Mouse Un-conjugated FACS, IHC (fro)   25 μg Log in to see 6 to 8 Days
$176.00
Details
Human Mouse Un-conjugated IF, WB Western blot analysis of CD49b (Integrin alpha2) on a HeLa cell lysate (Human cervical epitheloid carcinoma, ATCC CCL-2.2). Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of the anti-human CD49b antibody. Immunofluorescence staining of WiDr cells (Human colorectal adenocarcinoma, ATCC CCL-218). 50 μg Log in to see 5 to 6 Days
$205.42
Details
Human Mouse Un-conjugated Func, FACS   0.2 mg Log in to see 6 to 8 Days
$764.50
Details

ITGA2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Integrin alpha 2 Antibodies

  1. Human Monoclonal ITGA2 Primary Antibody for IF, WB - ABIN968317 : Emsley, King, Bergelson, Liddington: Crystal structure of the I domain from integrin alpha2beta1. in The Journal of biological chemistry 1997 (PubMed)
    Show all 5 references for ABIN968317

  2. Human Monoclonal ITGA2 Primary Antibody for FACS - ABIN118701 : Favaloro, Moraitis, Bradstock, Koutts: Co-expression of haemopoietic antigens on vascular endothelial cells: a detailed phenotypic analysis. in British journal of haematology 1990 (PubMed)
    Show all 5 references for ABIN118701

  3. Human Monoclonal ITGA2 Primary Antibody for Func, FACS - ABIN111324 : Bettaieb, Fromont, Rodet, Godeau, Duedari, Bierling: Brb, a platelet alloantigen involved in neonatal alloimmune thrombocytopenia. in Vox sanguinis 1991 (PubMed)
    Show all 5 references for ABIN111324

  4. Human Monoclonal ITGA2 Primary Antibody for FACS, IHC (fro) - ABIN319765 : Yoshino, Ami, Terao, Tashiro, Honda: Upgrading of flow cytometric analysis for absolute counts, cytokines and other antigenic molecules of cynomolgus monkeys (Macaca fascicularis) by using anti-human cross-reactive antibodies. in Experimental animals / Japanese Association for Laboratory Animal Science 2000 (PubMed)
    Show all 4 references for ABIN319765

  5. Human Monoclonal ITGA2 Primary Antibody for FACS - ABIN118700 : Ciarlet, Crawford, Cheng, Blutt, Rice, Bergelson, Estes: VLA-2 (alpha2beta1) integrin promotes rotavirus entry into cells but is not necessary for rotavirus attachment. in Journal of virology 2002 (PubMed)
    Show all 3 references for ABIN118700

  6. Human Monoclonal ITGA2 Primary Antibody for EIA, FACS - ABIN319775 : Fitter, Sincock, Jolliffe, Ashman: Transmembrane 4 superfamily protein CD151 (PETA-3) associates with beta 1 and alpha IIb beta 3 integrins in haemopoietic cell lines and modulates cell-cell adhesion. in The Biochemical journal 1999 (PubMed)
    Show all 2 references for ABIN319775

  7. Human Polyclonal ITGA2 Primary Antibody for EIA, WB - ABIN951336 : Jokinen, White, Salmela, Huhtala, Käpylä, Sipilä, Puranen, Nissinen, Kankaanpää, Marjomäki, Hyypiä, Johnson, Heino: Molecular mechanism of alpha2beta1 integrin interaction with human echovirus 1. in The EMBO journal 2010 (PubMed)
    Show all 2 references for ABIN951336

  8. Human Monoclonal ITGA2 Primary Antibody for EIA, FACS - ABIN118720 : Sincock, Fitter, Parton, Berndt, Gamble, Ashman et al.: PETA-3/CD151, a member of the transmembrane 4 superfamily, is localised to the plasma membrane and endocytic system of endothelial cells, associates with multiple integrins and modulates cell ... in Journal of cell science 1999 (PubMed)
    Show all 2 references for ABIN118720

  9. Human Monoclonal ITGA2 Primary Antibody for FACS - ABIN118698 : Mazurov, Vinogradov, Kabaeva, Antonova, Romanov, Vlasik, Antonov, Smirnov: A monoclonal antibody, VM64, reacts with a 130 kDa glycoprotein common to platelets and endothelial cells: heterogeneity in antibody binding to human aortic endothelial cells. in Thrombosis and haemostasis 1992 (PubMed)
    Show all 2 references for ABIN118698

More Antibodies against Integrin alpha 2 Interaction Partners

Zebrafish Integrin alpha 2 (ITGA2) interaction partners

  1. The differential expression of gpia and gpib in zebrafish suggests partition or divergence of gpi functions between the two duplicates.

  2. Comparison of glucose phosphase isomerase (GPI) genes from several vertebrates suggests that GPIs are being subjected to purifying selection to maintain the polarity and volume of the protein, but not its charge.

Mouse (Murine) Integrin alpha 2 (ITGA2) interaction partners

  1. HRG (show HRG Antibodies) binds to alpha2 integrin through low-affinity interactions in a heparin sulfate-independent manner, thereby blocking endothelial cells adhesion to collagen I.

  2. LG3, through interactions with alpha2beta1 integrins on recipient-derived cells leading to activation of ERK1/2 (show MAPK1/3 Antibodies) and increased migration, favors myointimal thickening

  3. IFN-gamma (show IFNG Antibodies) induces aberrant CD49b+ NK cell recruitment and pregnancy failure through regulating CX3CL1 (show CX3CL1 Antibodies).

  4. alphaIIbbeta3 regulates Syk (show SYK Antibodies) through an ITAM-independent pathway in mice and provide novel insight into the course of events underlying Syk (show SYK Antibodies) activation and hemITAM phosphorylation by CLEC-2 (show CLEC1B Antibodies)

  5. the collagen receptors DDR1 (show DDR1 Antibodies) and integrin a2b1 contribute to regulate GBM-maturation and to control matrix accumulation.

  6. alpha2beta1 integrin contributes to the pathogenesis of retinopathy. We describe a newly identified role for alpha2beta1 integrin in mediating hypoxia-induced Muller cell VEGF-A (show VEGFA Antibodies) production.

  7. required for the migration of memory CD4 (show CD4 Antibodies) T-cell precursors into their survival niches of the bone marrow

  8. alpha2beta1 integrin is expressed on synovial Th17 cells from CIA (show NCOA5 Antibodies) mice. Its neutralization reduced inflammation, cartilage degradation, bone erosion, RANKL (show TNFSF11 Antibodies) & IL-17 (show IL17A Antibodies) levels, & the numbers of osteoclasts and TH17 cells.

  9. TNF-alpha (show TNF Antibodies) stimulated cerebral pericyte remodeling in an alpha2 integrin-dependent manner.

  10. Blocking integrin alpha2beta1 and ERK 1 (show MAPK3 Antibodies)/2 pathways alleviated the effects of AMBN (show AMBN Antibodies) on osteoclast differentiation.

Human Integrin alpha 2 (ITGA2) interaction partners

  1. PFL-mediated downregulation of integrin and EGFR contributes to the inhibition of tumor growth in vitro and in vivo. This novel anti-cancer mechanism of PFL suggests that this lectin would be useful as an anti-cancer drug or an adjuvant for other drugs.

  2. HRG (show NRG1 Antibodies) binds to alpha2 integrin through low-affinity interactions in a heparin sulfate-independent manner, thereby blocking endothelial cells adhesion to collagen I.

  3. The Glycoprotein Ia (show MMRN1 Antibodies) C807T polymorphism might be a risk factor for the development and relapse of Acute Coronary Syndrome

  4. Data indicate that in recurrent spontaneous abortion patients, the expression levels of CD49b and LAG-3 (CD223 (show LAG3 Antibodies)) on CD14 (show NDUFA2 Antibodies)(+) mononuclear cells and the plasma level of transforming growth factor beta (TGF-beta) decreased obviously compared with normal females.

  5. Integrin alpha 2 and alpha 4 Yxxphi motifs interact with the endocytic clathrin adaptor, AP2 complex (show AP2B1 Antibodies).

  6. Epigenetic silencing of ITGA2 by MiR (show MLXIP Antibodies)-373 promotes cell migration in breast cancer.

  7. A highly bone metastatic RANKL (show TNFSF11 Antibodies)-overexpressing prostate cancer cell line, LNCaP(RANKL (show TNFSF11 Antibodies))used as a model to study increased adhesion of prostate cancer (PCa (show FLVCR1 Antibodies)) cells to collagens and found 3-D suspension culture and in vivo PCa (show FLVCR1 Antibodies) tumor growth restore AR through downregulation of AP-4 (show REPIN1 Antibodies), enhancing integrin alpha2 expression and adhesion to ColI which is rich in bone matrices.

  8. diabetic retinopathy is associated with ITGA2 and ITGB3 (show ITGB3 Antibodies) PlA1 (show POU2F3 Antibodies)/A2 polymorphisms (Meta-Analysis)

  9. Polymorphism of HPA- 5 is probably a risk factor for carotid atherosclerosis complicating T2DM.

  10. blockade of alpha2beta1 integrin with a neutralizing mAb inhibited IL-7 (show IL7 Antibodies)-induced bone loss and osteoclast numbers by reducing Th17 cell numbers in the bone marrow

Cow (Bovine) Integrin alpha 2 (ITGA2) interaction partners

  1. Flow induced alpha2beta1 activation in cells on collagen, but not on fibronectin or fibrinogen. Conversely, alpha5beta1 and alphavbeta3 are activated on fibronectin and fibrinogen, but not collagen.

  2. both the gpIb-VWF (show VWF Antibodies) interaction and the integrin alpha(2)beta(1)-collagen interaction contribute to platelet adhesion under high shear stress; integrin alpha(II (show GSTA3 Antibodies))beta(1) makes a greater contribution to adhesion to type I collagen because less VWF (show VWF Antibodies) is bound

Integrin alpha 2 (ITGA2) Antigen Profile

Protein Summary

This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with ITGA2

  • glucose phosphate isomerase a (gpia) antibody
  • integrin alpha 2 (Itga2) antibody
  • integrin, alpha 2 (Itga2) antibody
  • integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) (ITGA2) antibody
  • BR antibody
  • CD49B antibody
  • DX5 antibody
  • gpi antibody
  • GPIa antibody
  • HPA-5 antibody
  • PGI antibody
  • pgi-1 antibody
  • VLA-2 antibody
  • VLAA2 antibody
  • wu:fc02c05 antibody
  • zgc:86919 antibody

Protein level used designations for ITGA2

pgi1 , CD49 antigen-like family member B , GPIa , VLA-2 receptor, alpha 2 subunit , VLA-2 subunit alpha , collagen receptor , integrin alpha-2 , platelet membrane glycoprotein Ia , VLA2 receptor, alpha-2 subunit , human platelet alloantigen system 5 , platelet antigen Br , platelet glycoprotein GPIa , very late activation protein 2 receptor, alpha-2 subunit , VLA-2 alpha chain

GENE ID SPECIES
246094 Danio rerio
16398 Mus musculus
170921 Rattus norvegicus
3673 Homo sapiens
281872 Bos taurus
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