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ITAGV encodes integrin alpha chain V. Additionally we are shipping CD51 Proteins (11) and CD51 Kits (8) and many more products for this protein.
Showing 10 out of 251 products:
Mouse (Murine) Monoclonal CD51 Primary Antibody for FACS, WB - ABIN2663519
Maxfield, Moulder, Koning, Elbe, Stingl, Coligan, Shevach, Yokoyama: Murine T cells express a cell surface receptor for multiple extracellular matrix proteins. Identification and characterization with monoclonal antibodies. in The Journal of experimental medicine 1989
Show all 6 references for ABIN2663519
Human Monoclonal CD51 Primary Antibody for FACS - ABIN2660879
Nesbitt, Nesbit, Helfrich, Horton: Biochemical characterization of human osteoclast integrins. Osteoclasts express alpha v beta 3, alpha 2 beta 1, and alpha v beta 1 integrins. in The Journal of biological chemistry 1993
Show all 6 references for ABIN2660879
Mouse (Murine) Monoclonal CD51 Primary Antibody for IF, ICFC - ABIN2661109
Piali, Hammel, Uherek, Bachmann, Gisler, Dunon, Imhof: CD31/PECAM-1 is a ligand for alpha v beta 3 integrin involved in adhesion of leukocytes to endothelium. in The Journal of cell biology 1995
Show all 5 references for ABIN2661109
Human Monoclonal CD51 Primary Antibody for EIA, IF - ABIN1106450
Newton, Girgenti, Collier, Duman: Electroconvulsive seizure increases adult hippocampal angiogenesis in rats. in The European journal of neuroscience 2006
Show all 3 references for ABIN1106450
Chicken Monoclonal CD51 Primary Antibody for FACS, IP - ABIN319776
Simpson, Horton: Expression of the vitronectin receptor during embryonic development; an immunohistological study of the ontogeny of the osteoclast in the rabbit. in British journal of experimental pathology 1989
Show all 3 references for ABIN319776
Dog (Canine) Monoclonal CD51 Primary Antibody for IF, WB - ABIN968314
Bodary, McLean: The integrin beta 1 subunit associates with the vitronectin receptor alpha v subunit to form a novel vitronectin receptor in a human embryonic kidney cell line. in The Journal of biological chemistry 1990
Show all 3 references for ABIN968314
Human Polyclonal CD51 Primary Antibody for IF (p), IHC (p) - ABIN674784
Mondal, Barui, Chaudhuri: The relationship between the cyclic-RGDfK ligand and ?v?3 integrin receptor. in Biomaterials 2013
Show all 2 references for ABIN674784
Integrins alphavbeta6 and alphavbeta8 were expressed in non-overlapping patterns by keratinocytes and maintained the epidermal residence of Langerhans cells and tissue resident memory T cells by activating latent TGF-beta (show TGFB1 Antibodies).
This work identifies a previously unrecognized role for alphav and the autophagy components LC3 and atg5 in regulating TLR signalling and B-cell immunity.
These data support the hypothesis that IL-1beta (show IL1B Antibodies) was initially induced by hyperoxia; alphavbeta6 subsequently interacted with and activated TGF-beta1 (show TGFB1 Antibodies).
Gdf-5 (show GDF5 Antibodies) induced the expression of the alpha5 sub-unit, while Bmp-7 (show BMP7 Antibodies) induced the expression of the alphaV sub-unit.
These results suggest that phloretin was an inhibitor of actin podosomes and sealing zone, disrupting alpha5beta3 integrin-c-Src-Pyk2/Syk signaling pathway for the regulation of actin cytoskeletal organization in osteoclasts.
TN-C (show TNC Antibodies) may enhance inflammatory responses by accelerating macrophage migration and synthesis of proinflammatory/profibrotic cytokines via integrin alphaVbeta3/FAK (show PTK2 Antibodies)-Src (show SRC Antibodies)/NF-kappaB (show NFKB1 Antibodies), resulting in increased fibrosis.
Lung histology revealed aberrant elastin (show ELN Antibodies) production and impaired lung septation in oxygen-exposed lungs, while tropoelastin (show ELN Antibodies), integrin alphav, fibulin-1 (show FBLN1 Antibodies), fibulin-2 (show FBLN2 Antibodies) and fibulin-4 (show FBLN4 Antibodies) gene expression were elevated.
Knock-in mice expressing a CCN1 (show CCNA2 Antibodies) mutant that is unable to bind alphavbeta5/alphavbeta3 were impaired in ductular reaction. CCN1 (show CCNA2 Antibodies), acting through its alphav beta3/alphav beta5 binding site, is critical for survival after bile duct ligation.
These results suggest that integrin alphavbeta3 mediates the synergetic regulation of Cbfa1 (show RUNX2 Antibodies) transcription activity by gravity and IGF-1 (show IGF1 Antibodies) via PI3K signaling.
Angptl3 (show ANGPTL3 Antibodies) could induce actin filament rearrangement, mainly in lamellipodia formation, and that this process was mediated by integrin alpha(V)beta-mediated FAK (show PTK2 Antibodies) and PI3K phosphorylation and Rac1 activation.[ITGAV]
ERK (show EPHB2 Antibodies)-mediated transcription regulation of the alphav monomer is regulated by T3. Thyroid hormones are potent alphavbeta3-ligands, driving ovarian cancer cell proliferation.
The driving role of the tumour microenvironment on CRC (show CALR Antibodies) dissemination, here detected, and described, strengthens and adds new value to the concept that a5b1 integrin can be an appropriate and relevant therapeutic target for the control of CRC (show CALR Antibodies) metastases.
These findings suggest that enhanced integrin alphavbeta3 expression in addition to enhanced FGFR1 (show FGFR1 Antibodies) expression is critical for FGF1 (show FGF1 Antibodies) to augment TGF-beta1 (show TGFB1 Antibodies)-induced EMT (show ITK Antibodies) in mammary epithelial cells.
The combined impacts of alphav-integrin and HER2 (show ERBB2 Antibodies) influence the invasive phenotype of breast cancer cells.
alpha5beta1 and alphavbeta3 each mediate actin cytoskeletal remodeling in response to stiffening or cyclic stretching of the extracellular matrix.
Either mutation of two amino acids (D205A,D207A), or deletion of seven amino acids (Del202-208) of the Borrelia burgdorferi P66 (show POLD3 Antibodies) protein significantly reduced binding ability to integrin alphavbeta3.
Integrin alphavbeta3 is required for cathepsin B (show CTSB Antibodies)-induced hepatocellular carcinoma progression
These results suggest that melatonin exerts anti-migratory and anti-invasive effects on glioma cells in response to hypoxia via reactive oxygen species-alphavbeta3 integrin-FAK (show PTK2 Antibodies)/Pyk2 (show PTK2B Antibodies) signaling pathways.
Osteopontin (show SPP1 Antibodies) might promote a cancer stem cell-like phenotype via the alphavbeta3-NF-kappaB (show NFKB1 Antibodies)-HIF-1alpha (show HIF1A Antibodies) pathway in hepatocellular carcinoma.
The observed effects of shear stress on integrin alpha(v)beta(3) and p38 MAPK (show MAPK14 Antibodies) activation, as well as on FGF-2 (show FGF2 Antibodies) release could be mimicked by application of pancreatic elastase to static endothelial cells.
Inhibition of integrin alphavbeta3 prevents urokinase plasminogen (show PLG Antibodies) activator-mediated impairment of cerebrovasodilation after cerebral hypoxia/ischemia.
Flow induced alpha2beta1 activation in cells on collagen, but not on fibronectin or fibrinogen. Conversely, alpha5beta1 and alphavbeta3 are activated on fibronectin and fibrinogen, but not collagen.
specific substitutions show that the stable binding between foot-and-mouth disease virus VP1 and integrin alphavbeta6 is dependent on a helical structure and, specifically, two leucine residues at positions +1 and RGD +4 from the RGD motif.
These results demonstrate the critical role of the RhoA (show RHOA Antibodies)/alphavbeta5 integrin pathway in mediating Pseudomonas aeruginosa-induced lung vascular permeability.
ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8\; 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands\; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction. Alternative splicing results in multiple transcript variants.
integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
, alphav integrin
, integrin alpha V
, integrin alpha-V
, vitronectin receptor alpha polypeptide (VNRA)
, vitronectin receptor subunit alpha
, antigen identified by monoclonal antibody L230
, integrin alphaVbeta3
, Dnmt3l-ps1 pseudogene
, alphaV integrin
, integrin alpha v
, vitronectin receptor alpha subunit
, integrin alpha V subunit